Abstract: A new class of antibiotics, namely, mercaptoacetophenone aminohydrazones, their analogues, their method of preparation, their salts, and their use in cases of bacterial infections, either alone or with other compounds.

Abstract: The present invention relates to the formulation and the use of a cannabinoid, hyaluronate and certain botanical extracts or phytochemical materials to improve the health of skin. The formulations address the incompatibility between oil-soluble cannabinoids and aqueous herbal extracts, or water-soluble phytochemical components. Preferably, the botanical extract is selected from Opuntia ficus-indica, Carica papaya, Vasconcellea pubescens, Salvadora persica, Nigella sativa, Glycyrrhiza glabra, Camellia sinensis, and Aloe vera.

Abstract: New psilocybin and psilocin conjugates and their soluble salts with synergistic or additive therapeutic agents and stable formulations thereof, as well as their medical applications. The synergistic or additive conjugates may be used as drugs or prodrugs for treating various mental illness conditions related to the modulation or biased modulation of serotonin and related receptors, including but not limited to neurodegenerative disorders, depression, anxiety, obsessive compulsive disorder (OCD), cluster headaches, neuropathic pain and addiction.

Abstract: Cannabinoid esters and their soluble salts with synergistic or additive therapeutic counterparts and stable formulations thereof, as well as their edible, beverage and medicinal applications. The synergistic or additive cannabinoid esters may be used as drugs or prodrugs for treating various conditions related to the modulation or biased modulation of cannabinoid receptors, including but not limited to, pain and inflammation, arthritis, cancer, glaucoma, neurodegenerative disorders, multiple sclerosis, renal fibrosis, fibrotic disorder, mental health disorders, addiction, motor function disorders and gastrointestinal and metabolic disorders.

Abstract: Cannabinoid sulfate esters, their soluble salts and stable formulations thereof, as well as their edible, beverage and medicinal applications. The cannabinoid sulfate ester salts may be used as drugs or prodrugs for treating various conditions related to the modulation or biased modulation of cannabinoid receptors, including but not limited to, pain and inflammation, cancer, glaucoma, neurodegenerative disorders, multiple sclerosis, renal fibrosis, fibrotic disorder, addiction, motor function disorders and gastrointestinal and metabolic disorders.

Abstract: Disclosed herein are novel rigid cannabidiol (CBD) analogues and their formulations that modulate cannabinoid receptors, method(s) of preparation, methods of modulating cannabinoid receptors, and methods of treating various conditions related to the modulation of cannabinoid receptors, such as, pain and inflammation, cancer, glaucoma, neurodegenerative disorders, multiple sclerosis, renal fibrosis, fibrotic disorders, addiction, anxiety, insomnia, motor function disorders and gastrointestinal and metabolic disorders.

Abstract: A medicinal chewing gum has an inner core containing a first gum base and a first cannabinoid in a lipophilic nanosized form and an outer layer containing a second gum base and a second cannabinoid in a hydrophilic nanosized form, thereby providing quick release of the second cannabinoid in the outer layer and sustained release of the first cannabinoid in the inner layer. At least one of the inner core and the outer layer contains a synergistic compound having a synergistic effect with at least one of the first and second cannabinoids in the treatment of a medical condition.