Patents by Inventor Mahn Park

Mahn Park has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190262287
    Abstract: An anti-inflammatory composition is disclosed. The anti-inflammatory composition is be useful for a pharmaceutical composition or a cosmetic composition by not only having excellent stability on the skin and therefore being harmless to the human body, but also by controlling the expression of an inflammatory skin disease-related mediating factor and thereby exhibiting an excellent anti-inflammatory effect.
    Type: Application
    Filed: August 25, 2017
    Publication date: August 29, 2019
    Inventors: Ji Yeon PARK, Minhee KIM, Bu-Mahn PARK, Kyung Sook YOO, Sung Woo KIM, Hye Seong SHIN
  • Publication number: 20190247344
    Abstract: An anti-inflammatory composition is disclosed. The anti-inflammatory composition is useful for a pharmaceutical composition or a cosmetic composition by not only having excellent stability on the skin and therefore being harmless to the human body, but also by controlling the expression of an inflammatory skin disease-related mediating factor and thereby exhibiting an excellent anti-inflammatory effect.
    Type: Application
    Filed: August 25, 2017
    Publication date: August 15, 2019
    Inventors: Ji Yeon PARK, Minhee KIM, Bu-Mahn PARK, Kyung Sook YOO, Sung Woo KIM, Hye Seong SHIN
  • Patent number: 10287554
    Abstract: The present invention relates to an induced pluripotent stem cell model of Fabry disease, a preparation method thereof, and a use of the same for the study of Fabry disease development and for the screening of a therapeutic agent for the disease. Particularly, Fabry disease derived induced pluripotent stem cells (iPSCs), embryoid body (EB), and vascular cells were developed and differentiated from fibroblasts originated from Fabry disease patient, wherein the Fabry disease originated iPSCs displayed significantly reduced expression and activity of GLA protein therein, compared with the normal cells, resulting in the accumulation of globotriaosylceramide (Gb3, CD77). Also, the differentiation of vascular cells was induced from the Fabry disease originated iPSCs, and as a result the iPSCs were successfully differentiated into vascular endothelial cells and vascular smooth muscle cells with significantly expressing the marker protein.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: May 14, 2019
    Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Yong-mahn Han, Sang-Wook Park
  • Publication number: 20190125643
    Abstract: The present invention relates to an anti-aging composition. More specifically, the anti-aging composition according to the present invention is highly stable, harmless to the body, and effective in reducing wrinkles and improving elasticity of the skin due to the superb capability for stimulating collagen biosynthesis.
    Type: Application
    Filed: April 7, 2017
    Publication date: May 2, 2019
    Applicant: NEOPHARM CO., LTD.
    Inventors: Se Kyoo JEONG, Bu-Mahn PARK, Kyung Sook YOO, Sung Woo KIM, Hye Seong SHIN
  • Patent number: 10016351
    Abstract: The present invention relates to a composition for promoting hair growth or preventing hair loss and, specifically, to a composition, which has excellent stability for skin and no side effects, promotes hair growth, prevents hair loss through the delay of hair loss, and has an excellent hair growth effect.
    Type: Grant
    Filed: November 11, 2015
    Date of Patent: July 10, 2018
    Assignee: NEOPHARM CO., LTD.
    Inventors: Se Kyoo Jeong, Jong Hwan Bae, Bu Mahn Park, Dae Hwan Kim
  • Patent number: 9796665
    Abstract: The present invention relates to a novel pseudoceramide derivative, a pharmaceutically acceptable salt thereof or a solvate thereof, and a pharmaceutical or cosmetic composition containing the same as an active ingredient. The novel pseudoceramide derivative of the present invention is expected to be very useful for treating or preventing skin diseases by activating cannabinoid receptors. In addition, the novel pseudoceramide derivative, the pharmaceutically acceptable salt thereof or the solvate thereof, of the present invention, has a simple synthesis process compared with a known cannabinoid receptor antagonist so as to reduce processing time and curtail material costs, and thus is economical, and has advantages such as easy emulsification during the formulation of cosmetic products or medical supplies.
    Type: Grant
    Filed: September 1, 2014
    Date of Patent: October 24, 2017
    Assignee: NEOPHARM CO., LTD.
    Inventors: Se Kyoo Jeong, Bong-Woo Kim, Jeong Eun Jeon, Bu-Mahn Park
  • Patent number: 9783489
    Abstract: The present invention relates to a pharmaceutical composition and a cosmetic composition, which contain, as an active ingredient, a novel pseudo compound having similar structural characteristics to natural ceramide 1, or a pharmaceutically acceptable salt or solvate thereof, and the composition containing the compound of the present invention as an active ingredient has an excellent effect of enhancing a skin barrier function, thereby exhibiting an effect of alleviating inflammatory skin diseases, and has an excellent skin barrier improving function and an excellent skin moisturization enhancing effect.
    Type: Grant
    Filed: December 23, 2014
    Date of Patent: October 10, 2017
    Assignee: NEOPHARM CO., LTD.
    Inventors: Se Kyoo Jeong, Bong Woo Kim, Bu Mahn Park, Jeong Eun Jeon, Byung Gee Kim
  • Publication number: 20170239164
    Abstract: The present invention relates to a composition for promoting hair growth or preventing hair loss and, specifically, to a composition, which has excellent stability for skin and no side effects, promotes hair growth, prevents hair loss through the delay of hair loss, and has an excellent hair growth effect.
    Type: Application
    Filed: November 11, 2015
    Publication date: August 24, 2017
    Inventors: Se Kyoo JEONG, Jong Hwan BAE, Bu Mahn PARK, Dae Hwan KIM
  • Publication number: 20170036995
    Abstract: The present invention relates to a pharmaceutical composition and a cosmetic composition, which contain, as an active ingredient, a novel pseudo compound having similar structural characteristics to natural ceramide 1, or a pharmaceutically acceptable salt or solvate thereof, and the composition containing the compound of the present invention as an active ingredient has an excellent effect of enhancing a skin barrier function, thereby exhibiting an effect of alleviating inflammatory skin diseases, and has an excellent skin barrier improving function and an excellent skin moisturization enhancing effect.
    Type: Application
    Filed: December 23, 2014
    Publication date: February 9, 2017
    Inventors: Se Kyoo JEONG, Bong Woo KIM, Bu Mahn PARK, Jeong Eun JEON, Byung Gee KIM
  • Publication number: 20160354293
    Abstract: The present invention relates to a composition for promoting hair growth, preventing hair loss, or relieving inflammation, and more specifically, to a composition which has excellent stability to the skin, has no side effects, and exhibits excellent effects of hair growth promotion and hair loss prevention by promoting hair growth and delaying hair loss. The composition according to the present invention contains a material belonging to a ceramidase inhibitor, glycol, C1-C5 lower alcohol, and water, and thus the composition is safe, has no side effects, can be continuously used for a long period of time, has an excellent effect of hair growth promotion or hair loss prevention by significantly promoting hair growth, and exhibits an inflammation relieving effect as well as a hair growth promoting effect, additionally.
    Type: Application
    Filed: January 27, 2015
    Publication date: December 8, 2016
    Applicant: NEOPHARM CO., LTD.
    Inventors: Se Kyoo JEONG, Jong Hwan BAE, Bu Mahn PARK
  • Publication number: 20160272578
    Abstract: The present invention relates to a novel pseudoceramide derivative, a pharmaceutically acceptable salt thereof or a solvate thereof, and a pharmaceutical or cosmetic composition containing the same as an active ingredient. The novel pseudoceramide derivative of the present invention is expected to be very useful for treating or preventing skin diseases by activating cannabinoid receptors. In addition, the novel pseudoceramide derivative, the pharmaceutically acceptable salt thereof or the solvate thereof, of the present invention, has a simple synthesis process compared with a known cannabinoid receptor antagonist so as to reduce processing time and curtail material costs, and thus is economical, and has advantages such as easy emulsification during the formulation of cosmetic products or medical supplies.
    Type: Application
    Filed: September 1, 2014
    Publication date: September 22, 2016
    Applicant: NEOPHARM CO., LTD.
    Inventors: Se Kyoo JEONG, Bong-Woo KIM, Jeong Eun JEON, Bu-Mahn PARK
  • Patent number: 8957102
    Abstract: Provided are novel heterocyclic compounds useful as anti-cancer drugs by suppressing protein kinase activities of growth factor receptors such as c-Met, pharmaceutical compositions containing the same, and methods for using the compound.
    Type: Grant
    Filed: August 28, 2009
    Date of Patent: February 17, 2015
    Assignee: Neopharm Co., Ltd.
    Inventors: Tae-Seong Kim, Eunkyung Lee, Doyoung Kim, Bu-mahn Park, Jiyeon Park, JungJe Joo
  • Publication number: 20120289509
    Abstract: Provided are novel heterocyclic compounds useful as anti-cancer drugs by suppressing protein kinase activities of growth factor receptors such as c-Met, pharmaceutical compositions containing the same, and methods for using the compound.
    Type: Application
    Filed: July 6, 2012
    Publication date: November 15, 2012
    Applicant: NEOPHARM CO., LTD.
    Inventors: Tae-Seong KIM, Eunkyung LEE, Doyoung KIM, Bu-mahn PARK, Jiyeon PARK, JungJe JOO
  • Publication number: 20110183983
    Abstract: Provided are novel heterocyclic compounds useful as anti-cancer drugs by suppressing protein kinase activities of growth factor receptors such as c-Met, pharmaceutical compositions containing the same, and methods for using the compound.
    Type: Application
    Filed: August 28, 2009
    Publication date: July 28, 2011
    Applicant: NEOPHARM CO., LTD.
    Inventors: Tae-Seong Kim, Eunkyung Lee, Doyoung Kim, Bu-mahn Park, Jiyeon Park, JungJe Joo
  • Patent number: 7365533
    Abstract: A system and method to detect angular rotation, linear displacement and/or surface deformations is presented. The method is based on the ability of a linear polarized light to interact with magnetic materials and to change its polarization angle due to Faraday effect. A basic structure of the system consists of a magneto-optic (MO) film with a two-domain structure and a single domain wall which are generated by gradient magnetic field produced by opposite polarity permanent magnets placed near the film. An AC magnetic field applied perpendicular to the MO film surface causes the magnetic domain wall in the MO film to oscillate at the same frequency. This leads to a detected output AC modulated signal. By measuring the temporal changes in this signal, information on angular rotation, linear displacement and/or surface deformation can be obtained.
    Type: Grant
    Filed: July 21, 2006
    Date of Patent: April 29, 2008
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Seong-Jae Lee, Sang-Hoon Song, Yevgen Melikhov, Choon-Mahn Park, Hans Hauser, David Jiles
  • Publication number: 20070183788
    Abstract: A reflective semiconductor optical amplifier (RSOA) and an operating system based on a downstream optical signal reuse method with feed-forward current injection are provided. The RSOA has two active regions and includes a reflecting plane that reflects an input optical signal; and an optical amplifying semiconductor including a rear portion, which is positioned at a side of the reflecting plane and to which a signal having polarity opposite to that of the input optical signal is injected, and a front portion, which is positioned at a side opposite to the side of the rear portion facing the reflecting plane and which the input optical signal is passed though and a signal used to modulate a reflected input optical signal from the reflecting plane to an output optical signal is injected into.
    Type: Application
    Filed: January 9, 2007
    Publication date: August 9, 2007
    Inventors: Byoung Kim, Mahn Park, Seung Cho, Woo Lee, Jie Lee, Geon Jeong, Chul Kim
  • Publication number: 20070133990
    Abstract: A Reflective Semiconductor Optical Amplifier (RSOA) for compensating for light loss in an optical link, an RSOA module for improving polarization dependency using the RSOA, and a Passive Optical Network (PON) for increasing economical efficiency and practical use of a bandwidth using the RSOA are provided. The PON includes a central office comprising a plurality of optic sources transmitting a downstream signal and a plurality of first receivers receiving an upstream signal; at least one optical network terminal (ONT) including a second receiver receiving the downstream signal and an RSOA which receives the downstream signal, remodulates the downstream signal into the upstream signal, and transmits the upstream signal in loopback mode; and a remote node interfacing the central office with the ONT. The upstream signal and the downstream signal are transmitted between the remote node and the ONT via a single optical fiber. The remote node includes an optical power splitter at its port connected to the ONT.
    Type: Application
    Filed: December 4, 2006
    Publication date: June 14, 2007
    Inventors: Byoung Kim, Mahn Park, Woo-Ram Lee, Tae Kim
  • Publication number: 20070127538
    Abstract: Provided is an athermal external cavity laser (ECL), whose output optical power and output wavelength can be kept regular irrespective of temperature changes without using additional temperature controlling components. The ECL comprises: a semiconductor amplifier; an optical fiber comprising a core in which a Bragg grating is formed and a cladding surrounding the core; and a thermosetting polymer that fixes the optical fiber to a ferrule and has a negative thermooptical coefficient, wherein the thickness of the cladding surrounding the core in which the Bragg grating is formed is smaller than the portion of the cladding surrounding the portion of the core where the Bragg grating is not formed, and the thermosetting polymer the negative thermooptical coefficient surrounds the cladding.
    Type: Application
    Filed: December 5, 2006
    Publication date: June 7, 2007
    Inventors: Jie Lee, Mahn Park, Geon Jeong, Chul Kim, Seung Cho, Woo Lee, Byoung Kim
  • Publication number: 20070057668
    Abstract: A system and method to detect angular rotation, linear displacement and/or surface deformations is presented. The method is based on the ability of a linear polarized light to interact with magnetic materials and to change its polarization angle due to Faraday effect. A basic structure of the system consists of a magneto-optic (MO) film with a two-domain structure and a single domain wall which are generated by gradient magnetic field produced by opposite polarity permanent magnets placed near the film. An AC magnetic field applied perpendicular to the MO film surface causes the magnetic domain wall in the MO film to oscillate at the same frequency. This leads to a detected output AC modulated signal. By measuring the temporal changes in this signal, information on angular rotation, linear displacement and/or surface deformation can be obtained.
    Type: Application
    Filed: July 21, 2006
    Publication date: March 15, 2007
    Applicant: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Seong-Jae Lee, Sang-Hoon Song, Yevgen Melikhov, Choon-Mahn Park, Hans Hauser, David Jiles
  • Publication number: 20060104322
    Abstract: Hybrid-type external cavity lasers designed to have a semiconductor laser diode mounted on a planar waveguide platform by a flip-chip bonding method. The temperature independent external cavity laser comprises a semiconductor laser diode, a planar waveguide platform, and a thin film multi-layered reflection filter. The semiconductor laser diode includes an active region to generate light, and at least one light-emitting surface. The planar waveguide platform includes a substrate, a metallic pattern formed on a predetermined region of the substrate, a waveguide structure, and a trench portion. The waveguide structure comprises a lower clad layer, a core, and an upper clad layer sequentially stacked in this order on a region of the substrate excluding the predetermined region formed of the metallic pattern. The trench portion has opposite side surfaces on which the core is exposed.
    Type: Application
    Filed: May 4, 2005
    Publication date: May 18, 2006
    Inventors: Mahn Park, Byoung Kim