Patents by Inventor Mai Ito
Mai Ito has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20150246911Abstract: This fused heterocyclic compound represented in formula (1) has excellent effectiveness in pest control. In the formula, A1 represents —NR4—, etc.; A2 represents a nitrogen atom, etc.; R1 represents an ethyl group, a cyclopropyl group, or a cyclopropylmethyl group; R2 represents —S(O)mR6 or —C(R7)(CF3)2; R4 represents a C1-C6 alkyl group optionally having one or more halogen atoms; R6 represents a C1-C6 haloalkyl group; R7 represents a fluorine atom or a chlorine atom, and m and n each represents 0, 1 or 2.Type: ApplicationFiled: June 12, 2013Publication date: September 3, 2015Applicant: Sumitomo Chemical Company, LimitedInventors: Masaki Takahashi, Takamasa Tanabe, Mai Ito, Chie Shimizu, Yoshihiko Nokura
-
Patent number: 9120823Abstract: There is provided a compound having an excellent controlling effect on pests represented by the formula (1): wherein, A1 represents —NR7—, etc., A2 represents a nitrogen atom, etc., A3 represents a nitrogen atom, etc., R1 represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group X, etc., R2, R3 and R4 are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted by one or more halogen atoms, etc., R5 and R6 are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group X, etc., R7 represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group W, etc., n represents 0, 1 or 2, or an N-oxide thereof.Type: GrantFiled: March 26, 2015Date of Patent: September 1, 2015Assignee: Sumitomo Chemical Company, LimitedInventors: Masaki Takahashi, Takamasa Tanabe, Mai Ito, Yoshihiko Nokura
-
Patent number: 9120792Abstract: A compound represented by formula (1) and an N-oxide thereof have excellent pest control effect. (In the formula, Het to which R1—S(O)n is bonded represents a five-membered aromatic heterocyclic ring represented by formula H1, H2, H3 or H4 (wherein Y1 represents an oxygen atom or the like; Y2 represents an oxygen atom or the like; G1, G2 and G3 may be the same or different and each represents a nitrogen atom or the like; R1 represents a C1-C6 alkyl group which may have one or more atoms or groups selected from the group X, or the like; and n represents 0, 1 or 2); A1 represents an oxygen atom or the like; A2 represents a nitrogen atom or the like; A3 represents a nitrogen atom or the like; and R2 and R3 may be the same or different and each represents a C1-C6 chain hydrocarbon group which may have one or more atoms or groups selected from the group X, or the like.).Type: GrantFiled: May 23, 2013Date of Patent: September 1, 2015Assignee: Sumitomo Chemical Company, LimitedInventors: Yoshihiko Nokura, Mai Ito, Chie Shimizu, Hajime Mizuno
-
Publication number: 20150197532Abstract: There is provided a compound having an excellent controlling effect on pests represented by the formula (1): wherein, A1 represents —NR7—, etc., A2 represents a nitrogen atom, etc., A3 represents a nitrogen atom, etc., R1 represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group X, etc., R2, R3 and R4 are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted by one or more halogen atoms, etc., R5 and R6 are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group X, etc., R7 represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group W, etc., n represents 0, 1 or 2, or an N-oxide thereof.Type: ApplicationFiled: March 26, 2015Publication date: July 16, 2015Inventors: Masaki TAKAHASHI, Takamasa TANABE, Mai ITO, Yoshihiko NOKURA
-
Publication number: 20150191474Abstract: The fused heterocyclic compound represented by formula (1) has excellent effectiveness in pest control. In the formula (1), J represents formula J1, J2, J3, J4, J5 or J6; A1; A2; A3; A4; A5; B1; B2; B4; B5; and B6 each represent a nitrogen atom, etc.; B3 represents NR5, etc.; R1 represents a C1-C6 chain hydrocarbon group, etc., optionally having one or more atoms or groups selected from group X; the pairs R2 and R3 and R5 and R6 are the same or different, and represent a C1-C6 chain hydrocarbon group, etc., optionally having one or more atoms or groups selected from group X; R4 represents a C1-C6 chain hydrocarbon group, etc., optionally having one or more atoms or groups selected from group W; and n represents 0, 1, or 2.Type: ApplicationFiled: June 10, 2013Publication date: July 9, 2015Inventors: Masaki Takahashi, Mai Ito, Yoshihiko Nokura, Takamasa Tanabe, Chie Shimizu
-
Publication number: 20150181880Abstract: The fused heterocyclic compound represented by formula (1), or an N-oxide thereof, has excellent effectiveness in pest control. In the formula G1 represents a nitrogen atom, etc.; G2 represents a nitrogen atom, etc.; A1 represents a nitrogen atom, etc.; A2 represents a nitrogen atom, etc.; A3 represents a nitrogen atom, etc.; A4 represents a nitrogen atom, etc.; A5 represents a nitrogen atom, etc.; R1 represents a C1-C6 chain hydrocarbon group, etc., optionally having one or more atoms or groups selected from group X; R2, R3 and R4 are the same or different, and represent a C1-C6 chain hydrocarbon group, etc., optionally having one or more atoms or groups selected from group X; R5 and R6 are the same or different, and represent a C1-C6 chain hydrocarbon group, etc., optionally having one or more atoms or groups selected from group X; and n represents 0, 1, 2.Type: ApplicationFiled: June 10, 2013Publication date: July 2, 2015Applicant: Sumitomo Chemical Company, LimitedInventors: Masaki Takahashi, Mai Ito, Yoshihiko Nokura, Takamasa Tanabe, Chie Shimizu
-
Publication number: 20150166573Abstract: This fused heterocyclic compound represented by formula (1) (in the formula, G1 represents a nitrogen atom or the like, G2 represents a nitrogen atom or the like, A1 represents a nitrogen atom or the like, A2 represents a nitrogen atom or the like, A3 represents —NR8— or the like, A4 represents a nitrogen atom or the like, A5 represents a nitrogen atom or the like, R1 represents a C1-C6 chain hydrocarbon group or the like optionally having one or more atoms or groups selected from a group X, R2 and R3 are the same or different and represent a C1-C6 chain hydrocarbon group or the like optionally having one or more atoms or groups selected from the group X, R8 represents a C1-C6 chain hydrocarbon group or the like optionally having one or more atoms or groups selected from a group W, and n represents 0, 1 or 2.), or an N-oxide thereof, is very effective for pest control.Type: ApplicationFiled: May 23, 2013Publication date: June 18, 2015Inventors: Masaki Takahashi, Mai Ito, Yoshihiko Nokura, Takamasa Tanabe, Chie Shimizu
-
Patent number: 9018134Abstract: There is provided a compound having an excellent controlling effect on pests represented by the formula (1): wherein, A1 represents —NR7—, etc., A2 represents a nitrogen atom, etc., A3 represents a nitrogen atom, etc., R1 represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group X, etc., R2, R3 and R4 are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted by one or more halogen atoms, etc., R5 and R6 are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group X, etc., R7 represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group W, etc., n represents 0, 1 or 2, or an N-oxide thereof.Type: GrantFiled: August 3, 2012Date of Patent: April 28, 2015Assignee: Sumitomo Chemical Company, LimitedInventors: Masaki Takahashi, Takamasa Tanabe, Mai Ito, Yoshihiko Nokura, Atsushi Iwata
-
Publication number: 20150094329Abstract: A compound represented by formula (1) and an N-oxide thereof have excellent pest control effect. (In the formula, Het to which R1—S(O)n is bonded represents a five-membered aromatic heterocyclic ring represented by formula H1, H2, H3 or H4 (wherein Y1 represents an oxygen atom or the like; Y2 represents an oxygen atom or the like; G1, G2 and G3 may be the same or different and each represents a nitrogen atom or the like; R1 represents a C1-C6 alkyl group which may have one or more atoms or groups selected from the group X, or the like; and n represents 0, 1 or 2); A1 represents an oxygen atom or the like; A2 represents a nitrogen atom or the like; A3 represents a nitrogen atom or the like; and R2 and R3 may be the same or different and each represents a C1-C6 chain hydrocarbon group which may have one or more atoms or groups selected from the group X, or the like.Type: ApplicationFiled: May 23, 2013Publication date: April 2, 2015Inventors: Yoshihiko Nokura, Mai Ito, Chie Shimizu, Hajime Mizuno
-
Publication number: 20140364444Abstract: A fused heterocyclic compound the formula (1): wherein A1 represents —NR8—, and the like; A2 represents a nitrogen atom, and the like; A3 represents a nitrogen atom, and the like; R1 represents a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group X, and the like; R2, R3, R4, and R5 are same or different and represent independently a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, and the like; R6 and R7 are same or different and represent independently a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group X, and the like; R8 represents a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group W, and the like; n represents 0, 1 or 2. The compound has an excellent activity of controlling pests.Type: ApplicationFiled: August 21, 2014Publication date: December 11, 2014Inventors: Hayato TAKYO, Masaki TAKAHASHI, Takamasa TANABE, Yoshihiko NOKURA, Mai ITO, Atsushi IWATA
-
Patent number: 8853238Abstract: A fused heterocyclic compound the formula (1): wherein A1 represents —NR8—, and the like; A2 represents a nitrogen atom, and the like; A3 represents a nitrogen atom, and the like; R1 represents a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group X, and the like; R2, R3, R4, and R5 are same or different and represent independently a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, and the like; R6 and R7 are same or different and represent independently a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group X, and the like; R8 represents a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group W, and the like; n represents 0, 1 or 2. The compound has an excellent activity of controlling pests.Type: GrantFiled: December 22, 2011Date of Patent: October 7, 2014Assignee: Sumitomo Chemical Company, LimitedInventors: Hayato Takyo, Masaki Takahashi, Takamasa Tanabe, Yoshihiko Nokura, Mai Ito, Atsushi Iwata
-
Publication number: 20140194290Abstract: There is provided a compound having an excellent controlling effect on pests represented by the formula (1): wherein, A1 represents —NR7—, etc., A2 represents a nitrogen atom, etc., A3 represents a nitrogen atom, etc., R1 represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group X, etc., R2, R3 and R4 are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted by one or more halogen atoms, etc., R5 and R6 are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group X, etc., R7 represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group W, etc., n represents 0, 1 or 2, or an N-oxide thereof.Type: ApplicationFiled: August 3, 2012Publication date: July 10, 2014Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Masaki Takahashi, Takamasa Tanabe, Mai Ito, Yoshihiko Nokura, Atsushi Iwata
-
Publication number: 20140171493Abstract: The present invention provides, as an enzyme which can be used for enzyme replacement therapy for Fabry disease, a protein having ?-galactosidase activity, which shows no allergic adverse side effect, shows a high stability in blood, and can be easily incorporated into a cell of an affected organ. The protein of the present invention is a protein which has acquired ?-galactosidase activity by changing the structure of the active site of wild-type human ?-N-acetylgalactosaminidase.Type: ApplicationFiled: January 23, 2014Publication date: June 19, 2014Applicants: ALTIF LABORATORIES, TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCEInventors: Hitoshi Sakuraba, Youichi Tajima, Mai Ito, Seiichi Aikawa, Fumiko Aikawa
-
Patent number: 8668907Abstract: The present invention provides, as an enzyme which can be used for enzyme replacement therapy for Fabry disease, a protein having ?-galactosidase activity, which shows no allergic adverse side effect, shows a high stability in blood, and can be easily incorporated into a cell of an affected organ. The protein of the present invention is a protein which has acquired ?-galactosidase activity by changing the structure of the active site of wild-type human ?-N-acetylgalactosaminidase.Type: GrantFiled: November 2, 2012Date of Patent: March 11, 2014Assignees: Tokyo Metropolitan Institute of Medical Science, Altif LaboratoriesInventors: Hitoshi Sakuraba, Youichi Tajima, Mai Ito, Seiichi Aikawa, Fumiko Aikawa
-
Publication number: 20140018373Abstract: A fused heterocyclic compound the formula (1): wherein A1 represents —NR8—, and the like; A2 represents a nitrogen atom, and the like; A3 represents a nitrogen atom, and the like; R1 represents a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group X, and the like; R2, R3, R4, and R5 are same or different and represent independently a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, and the like; R6 and R7 are same or different and represent independently a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group X, and the like; R8 represents a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group W, and the like; n represents 0, 1 or 2. The compound has an excellent activity of controlling pests.Type: ApplicationFiled: December 22, 2011Publication date: January 16, 2014Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Hayato Takyo, Masaki Takahashi, Takamasa Tanabe, Yoshihiko Nokura, Mai Ito, Atsushi Iwata
-
Patent number: 8323640Abstract: The present invention provides, as an enzyme which can be used for enzyme replacement therapy for Fabry disease, a protein having ?-galactosidase activity, which shows no allergic adverse side effect, shows a high stability in blood, and can be easily incorporated into a cell of an affected organ. The protein of the present invention is a protein which has acquired ?-galactosidase activity by changing the structure of the active site of wild-type human ?-N-acetylgalactosaminidase.Type: GrantFiled: March 21, 2011Date of Patent: December 4, 2012Assignees: Tokyo Metropolitan Organization For Medical Research, Altif LaboratoriesInventors: Hitoshi Sakuraba, Youichi Tajima, Mai Ito, Seiichi Aikawa, Fumiko Aikawa
-
Publication number: 20110171198Abstract: The present invention provides, as an enzyme which can be used for enzyme replacement therapy for Fabry disease, a protein having ?-galactosidase activity, which shows no allergic adverse side effect, shows a high stability in blood, and can be easily incorporated into a cell of an affected organ. The protein of the present invention is a protein which has acquired ?-galactosidase activity by changing the structure of the active site of wild-type human ?-N-acetylgalactosaminidase.Type: ApplicationFiled: March 21, 2011Publication date: July 14, 2011Applicants: TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH, ALTIF LABORATORIESInventors: Hitoshi Sakuraba, Youichi Tajima, Mai Ito, Seiichi Aikawa, Fumiko Aikawa
-
Patent number: 7935336Abstract: The present invention provides, as an enzyme which can be used for enzyme replacement therapy for Fabry disease, a protein having ?-galactosidase activity, which shows no allergic adverse side effect, shows a high stability in blood, and can be easily incorporated into a cell of an affected organ. The protein of the present invention is a protein which has acquired ?-galactosidase activity by changing the structure of the active site of wild-type human ?-N-acetylgalactosaminidase.Type: GrantFiled: November 17, 2006Date of Patent: May 3, 2011Assignees: Tokyo Metropolitan Organization for Medical Research, ALTIF LaboratoriesInventors: Hitoshi Sakuraba, Youichi Tajima, Mai Ito, Seiichi Aikawa, Fumiko Aikawa
-
Publication number: 20100166728Abstract: The present invention provides, as an enzyme which can be used for enzyme replacement therapy for Fabry disease, a protein having ?-galactosidase activity, which shows no allergic adverse side effect, shows a high stability in blood, and can be easily incorporated into a cell of an affected organ. The protein of the present invention is a protein which has acquired ?-galactosidase activity by changing the structure of the active site of wild-type human ?-N-acetylgalactosaminidase.Type: ApplicationFiled: November 17, 2006Publication date: July 1, 2010Applicants: TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH, ALTIF LABORATORIESInventors: Hitoshi Sakuraba, Youichi Tajima, Mai Ito, Seiichi Aikawa, Fumiko Aikawa
-
Publication number: 20090297592Abstract: It is an object of the present invention to provide an enzyme preparation which is excellent in stability in blood (blood residence) and in transfer to a target organ (targeting property), and can be used effectively in enzyme replacement therapy or the like. This problem is solved by a lipid vesicle composition wherein vesicles composed of a lipid bilayer membrane are encapsulating an enzyme, the composition being capable of retaining stably the activity of the enzyme even outside the stable pH range of the enzyme.Type: ApplicationFiled: May 11, 2006Publication date: December 3, 2009Applicants: JCR Pharmaceuticals Co., Ltd., Tokyo Metropolitan Organization for Medical ResearchInventors: Hitoshi Sakuraba, Youichi Tajima, Ikuo Kawashima, Mai Ito, Shinji Takeoka, Katsuji Ohta, Manabu Ito, Atsushi Mizuno