Patents by Inventor Mai Trang

Mai Trang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nitrogen-containing analogs of salinomycin, synthesis and use against cancer stem cells and malaria
    Patent number: 10287298
    Abstract: The present invention concerns compounds of formula (I), enantiomers, mixture of enantiomers, diastereoisomers and mixture of diasteroisomers thereof formula (I): wherein at least one of W, X and Y is selected from the group consisting of —NR1R2; —NR3—(CH2)n—NR4R5; —O—(CH2)n—NR4R5; —NR3—(CH2)n—N?R6R7R8; and —O—(CH2)n—N?R6R7R8 and Z is a functional group capable of chelating iron salts. The present invention also concerns the compounds of formula (I) for use as a drug, in particular, in the treatment of cancer and malaria.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: May 14, 2019
    Assignees: Centre National de la Recherche Scientifique (CNRS), Institut National de la Sante et de la Recherche Medicale (INSERM), Universite Paris Descartes
    Inventors: Maryam Mehrpour, Raphael Rodriguez, Antje Hienzsch, Mai Trang, Ahmed Hamai
  • TOTAL CELLULAR IRON AS A MARKER OF CANCER STEM CELLS AND USES THEREOF
    Publication number: 20190101549
    Abstract: The present invention relates to a novel use of total cellular iron, preferably under the form of ferrous iron (Fe2+), as a marker of cancer stem cells (CSCs). The invention also relates to methods using said iron marker, in particular for metastatic cancer diagnosis or treatment, for screening for compounds of interest, as well as for killing CSCs.
    Type: Application
    Filed: March 8, 2017
    Publication date: April 4, 2019
    Applicants: Institut National de la Sante et de la Recherche Medicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universite Paris Descartes
    Inventors: Maryam Mehrpour, Raphael Rodriguez, Ahmed Hamai, Mai Trang
  • NITROGEN-CONTAINING ANALOGS OF SALINOMYCIN, SYNTHESIS AND USE AGAINST CANCER STEM CELLS AND MALARIA
    Publication number: 20170253610
    Abstract: The present invention concerns compounds of formula (I), enantiomers, mixture of enantiomers, diastereoisomers and mixture of diasteroisomers thereof formula (I): wherein at least one of W, X and Y is selected from the group consisting of —NR1R2; —NR3—(CH2)n—NR4R5; —O—(CH2)n—NR4R5; —NR3—(CH2)n—N?R6R7R8; and —O—(CH2)n—N?R6R7R8 and Z is a functional group capable of chelating iron salts. The present invention also concerns the compounds of formula (I) for use as a drug, in particular, in the treatment of cancer and malaria.
    Type: Application
    Filed: September 14, 2015
    Publication date: September 7, 2017
    Applicants: Centre National de la Recherche Scientifique (CNRS), Institut National de la Sante et de la Recherche M edicale (INSERM), Universite Paris Descartes, Uiversite Paris-SUD
    Inventors: Maryam Mehrpour, Raphael Rodriguez, Antje Hienzsch, Mai Trang, Ahmed Hamai
  • Method for managing decisions, method for constructing a decision tree, central manager, intermediate manager, terminal and corresponding computer program products
    Patent number: 7991869
    Abstract: A method is provided for managing decisions between a central manager and at least one terminal in an architecture of networks distributed and prioritized according to N levels, with N?2. The central manager is included in a level of rank N. The terminal is included in a level of rank 1. The method includes a step of distributing a decision tree constructed by the central manager and supported by the architecture.
    Type: Grant
    Filed: March 30, 2006
    Date of Patent: August 2, 2011
    Assignee: France Telecom
    Inventors: Servane Bonjour, Christophe Dousson, Mai Trang Thi Nguyen
  • METHOD FOR MANAGING DECISIONS, METHOD FOR CONSTRUCTING A DECISION TREE, CENTRAL MANAGER, INTERMEDIATE MANAGER, TERMINAL AND CORRESPONDING COMPUTER PROGRAM PRODUCTS
    Publication number: 20090119392
    Abstract: A method is provided for managing decisions between a central manager and at least one terminal in an architecture of networks distributed and prioritized according to N levels, with N?2. The central manager is included in a level of rank N. The terminal is included in a level of rank 1. The method includes a step of distributing a decision tree constructed by the central manager and supported by the architecture.
    Type: Application
    Filed: March 30, 2006
    Publication date: May 7, 2009
    Applicant: France Telecom
    Inventors: Servane Bonjour, Christophe Dousson, Mai Trang Thi Nguyen