Patents by Inventor Mai Zhang

Mai Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240009306
    Abstract: The present invention provides glycan-interacting antibodies and methods for producing glycan-interacting antibodies useful in the treatment and prevention of human disease, including cancer. Such glycan-interacting antibodies include monoclonal antibodies, derivatives, and fragments thereof as well as compositions and kits comprising them. In some embodiments, the present invention provides an antibody having a heavy chain with an amino acid sequence comprising at least 95% sequence identity to SEQ ID NO: 63 and having a light chain with an amino acid sequence comprising at least 95% sequence identity to SEQ ID NO: 64.
    Type: Application
    Filed: November 7, 2022
    Publication date: January 11, 2024
    Applicant: Seagen Inc.
    Inventors: Ana Paula Galvao da Silva, Julie DeSander, Jeffrey Behrens, Darius Ghaderi, Mai Zhang, Kristan Meetze
  • Publication number: 20240002422
    Abstract: The invention provides methods and tools, for example, glycan arrays, for the analysis of glycans and anti-glycan antibodies. Embodiments of the invention may be used to detect proteins, antibodies, diseases and/or pathogenic agents. In other embodiments, methods of the invention are used to develop or optimize arrays and antibodies.
    Type: Application
    Filed: February 28, 2023
    Publication date: January 4, 2024
    Applicant: Seagen Inc.
    Inventors: Ana Paula Galvao da Silva, Mai Zhang, Darius Ghaderi, Julie DeSander, Jeffrey Behrens, Jillian M. Prendergast
  • Patent number: 11312659
    Abstract: The invention discloses a calcium-alumino-silicate-hydrate nano-seeds suspension and preparation method thereof. The preparation method of calcium-alumino-silicate-hydrate nano-seeds suspension includes the following steps: dropwise adding the aqueous solution of calcium source, the aqueous solution of silicon source and the aqueous solution of aluminum source to the solution of polycarboxylate superplasticizer, and adjusting the pH value to 10.0˜13.5, and continuously stirring to obtain the calcium-alumino-silicate-hydrate nano-seeds suspension. The beneficial effect in the present invention is: the calcium-alumino-silicate-hydrate nano-seeds has small particle size, good dispersion stability, and it can effectively improve the early hydration and mechanical performance of cement-based materials, and has good application prospects; the preparation process is simple, without washing, drying, ultrasonic dispersion and other subsequent processes, suitable for large-scale production.
    Type: Grant
    Filed: October 13, 2020
    Date of Patent: April 26, 2022
    Assignee: WUHAN UNIVERSITY OF TECHNOLOGY
    Inventors: Fazhou Wang, Chuanlin Hu, Fubing Zou, Shuguang Hu, Mai Zhang
  • Publication number: 20220057402
    Abstract: The present invention provides glycan-interacting antibodies and methods for producing glycan-interacting antibodies useful in the treatment and prevention of human disease, including cancer. Such glycan-interacting antibodies include monoclonal antibodies, derivatives, and fragments thereof as well as compositions and kits comprising them. Further provided are methods of using glycan-interacting antibodies to target cells and treat disease.
    Type: Application
    Filed: May 26, 2021
    Publication date: February 24, 2022
    Applicant: Seagen Inc.
    Inventors: Ana Paula Galvao da Silva, Darius Ghaderi, Mai Zhang, Kristan Meetze, Julie DeSander, Jeffrey Behrens, David A. Eavarone, Jillian M. Prendergast
  • Publication number: 20210276919
    Abstract: The invention discloses a calcium-alumino-silicate-hydrate nano-seeds suspension and preparation method thereof. The preparation method of calcium-alumino-silicate-hydrate nano-seeds suspension includes the following steps: dropwise adding the aqueous solution of calcium source, the aqueous solution of silicon source and the aqueous solution of aluminum source to the solution of polycarboxylate superplasticizer, and adjusting the pH value to 10.0˜13.5, and continuously stirring to obtain the calcium-alumino-silicate-hydrate nano-seeds suspension. The beneficial effect in the present invention is: the calcium-alumino-silicate-hydrate nano-seeds has small particle size, good dispersion stability, and it can effectively improve the early hydration and mechanical performance of cement-based materials, and has good application prospects; the preparation process is simple, without washing, drying, ultrasonic dispersion and other subsequent processes, suitable for large-scale production.
    Type: Application
    Filed: October 13, 2020
    Publication date: September 9, 2021
    Inventors: Fazhou Wang, Chuanlin Hu, Fubing Zou, Shuguang Hu, Mai Zhang
  • Publication number: 20210017213
    Abstract: The invention provides methods and tools, for example, glycan arrays, for the analysis of glycans and anti-glycan antibodies. Embodiments of the invention may be used to detect proteins, antibodies, diseases and/or pathogenic agents. In other embodiments, methods of the invention are used to develop or optimize arrays and antibodies.
    Type: Application
    Filed: April 16, 2020
    Publication date: January 21, 2021
    Applicant: Seattle Genetics, Inc.
    Inventors: Ana Paula Galvao da Silva, Mai Zhang, Darius Ghaderi, Julie DeSander, Jeffrey Behrens, Jillian M. Prendergast
  • Publication number: 20210011021
    Abstract: The present invention provides glycan-interacting antibodies and methods for producing glycan-interacting antibodies useful in the treatment and prevention of human disease, including cancer. Such glycan-interacting antibodies include monoclonal antibodies, derivatives, and fragments thereof as well as compositions and kits comprising them. Further provided are methods of using glycan-interacting antibodies to target cells and treat disease.
    Type: Application
    Filed: February 14, 2020
    Publication date: January 14, 2021
    Applicant: Seattle Genetics, Inc.
    Inventors: Ana Paula Galvao da Silva, Darius Ghaderi, Mai Zhang, Kristan Meetze, Julie DeSander, Jeffrey Behrens, David A. Eavarone, Jillian M. Prendergast
  • Publication number: 20200276306
    Abstract: The present invention provides glycan-interacting antibodies and methods for producing glycan-interacting antibodies useful in the treatment and prevention of human disease, including cancer. Such glycan-interacting antibodies include mono clonal antibodies, derivatives, and fragments thereof as well as compositions and kits comprising them. In some embodiments, the present invention provides an antibody having a heavy chain with an amino acid sequence comprising at least 95% sequence identity to SEQ ID NO: 63 and having a light chain with an amino acid sequence comprising at least 95% sequence identity to SEQ ID NO: 64.
    Type: Application
    Filed: January 14, 2020
    Publication date: September 3, 2020
    Applicant: Seattle Genetics, Inc.
    Inventors: Ana Paula Galvao da Silva, Julie DeSander, Jeffrey Behrens, Darius Ghaderi, Mai Zhang, Kristan Meetze
  • Publication number: 20180280504
    Abstract: The present invention provides glycan-interacting antibodies and methods for producing glycan-interacting antibodies useful in the treatment and prevention of human disease, including cancer. Such glycan-interacting antibodies include monoclonal antibodies, derivatives, and fragments thereof as well as compositions and kits comprising them.
    Type: Application
    Filed: October 9, 2015
    Publication date: October 4, 2018
    Inventors: Ana Paula Galvao da Silva, Julie DeSander, Jeffrey Behrens, Darius Ghaderi, Mai Zhang, Kristan Meetze
  • Publication number: 20170305950
    Abstract: The invention provides methods and tools, for example, glycan arrays, for the analysis of glycans and anti-glycan antibodies. Embodiments of the invention may be used to detect proteins, antibodies, diseases and/or pathogenic agents. In other embodiments, methods of the invention are used to develop or optimize arrays and antibodies.
    Type: Application
    Filed: October 9, 2015
    Publication date: October 26, 2017
    Inventors: Ana Paula Galvao da Silva, Mai Zhang, Darius Ghaderi, Julie DeSander, Jeffrey Behrens, Jillian M. Prendergast
  • Publication number: 20170306046
    Abstract: The present invention provides glycan-interacting antibodies and methods for producing glycan-interacting antibodies useful in the treatment and prevention of human disease, including cancer. Such glycan-interacting antibodies include monoclonal antibodies, derivatives, and fragments thereof as well as compositions and kits comprising them. Further provided are methods of using glycan-interacting antibodies to target cells and treat disease.
    Type: Application
    Filed: November 12, 2015
    Publication date: October 26, 2017
    Inventors: Ana Paula Galvao daSilva, Darius Ghaderi, Mai Zhang, Kristan Meetze, Julie DeSander, Jeffrey Behrens, David A. Eavarone, Jillian M. Prendergast, Alexey Alexandrovich Lugovskoy
  • Publication number: 20160264684
    Abstract: The present invention provides glycan-interacting antibodies and methods for producing glycan-interacting antibodies useful in the treatment and prevention of human disease, including cancer. Such glycan-interacting antibodies include monoclonal antibodies, derivatives and fragments thereof as well as compositions and kits comprising them.
    Type: Application
    Filed: October 10, 2014
    Publication date: September 15, 2016
    Applicant: SIAMAB THERAPEUTICS, INC.
    Inventors: Ana Paula Galvao da Silva, Mai Zhang, Darius Ghaderi, Intan Purnajo, Julie DeSander, Jeffrey Behrens
  • Publication number: 20160106799
    Abstract: Embodiments of the present invention provide compositions and methods for the modulation of sialic acid levels. In some embodiments, compositions disclosed herein comprise nutraceuticals as functional agents.
    Type: Application
    Filed: May 29, 2014
    Publication date: April 21, 2016
    Applicant: SIAMAB THERAPEUTICS, INC.
    Inventors: Mai Zhang, Darius Ghaderi, Jeffrey Behrens, Julie DeSander, Ajit Varki