Patents by Inventor Maicol Mancini

Maicol Mancini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for treating cancer resistant to a tyrosine kinase inhibitor (TKI)
    Patent number: 10011659
    Abstract: Methods of treating a subject having cancer exhibiting a resistance to a tyrosine kinase inhibitor (TKI) are provided. Accordingly, there is provided a method comprising administering to the subject a therapeutically effective amount of antibodies comprising an anti-EGFR antibody, an anti-HER2 antibody and an anti-HER3 antibody. Also provided are compositions and articles of manufacture for treating cancer resistance to a TKI. Also provided are methods of treating non-resistant tumors.
    Type: Grant
    Filed: December 2, 2015
    Date of Patent: July 3, 2018
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Yosef Yarden, Maicol Mancini, Nadège Gaborit
  • COMPOSITIONS AND METHODS FOR TREATING CANCER RESISTANT TO A TYROSINE KINASE INHIBITOR (TKI)
    Publication number: 20160152712
    Abstract: Methods of treating a subject having cancer exhibiting a resistance to a tyrosine kinase inhibitor (TKI) are provided. Accordingly, there is provided a method comprising administering to the subject a therapeutically effective amount of antibodies comprising an anti-EGFR antibody, an anti-HER2 antibody and an anti-HER3 antibody. Also provided are compositions and articles of manufacture for treating cancer resistance to a TKI. Also provided are methods of treating non-resistant tumors.
    Type: Application
    Filed: December 2, 2015
    Publication date: June 2, 2016
    Inventors: Yosef YARDEN, Maicol Mancini, Nadège Gaborit