Abstract: In a rim replacing method for a tire testing machine of the present invention, one pair of the rims satisfying predetermined conditions relative to a test tire are selected, from among a pair of rims attached to the upper and lower spindles and plural pairs of rims loaded in a rim replacing device, as object rims, and rim replacement is performed if the rims loaded in the rim replacing device are selected as the object rims, so that the nonuniformity of rim can be suitably measured. The predetermined conditions include a condition in which a diameter of bead portions of the tire conveyed into the tire testing machine corresponds to a diameter of the object rims, and a condition in which a width of the bead portions of the tire conveyed into the tire testing machine falls within a range in which a space between the object rims is adjustable.

Abstract: An evaluating method includes an evaluating step of evaluating a future risk of relapse of ulcerative colitis for a subject to be evaluated having ulcerative colitis in a remission phase using a concentration value of histidine, albumin, hemoglobin, or glutamic acid in blood of the subject.

Abstract: A tire testing machine includes a test station in which spindles to attach a tire on which a barcode is installed are provided, and first and second belt conveyors that feed the tire into a center position of the spindles. In order to stably grasp a position of identifying information of the tire and stop rotation of the tire at an arbitrary desired angle, before applying a lubricant to a bead portion on an inner periphery of the tire conveyed to the first belt conveyors by means of the lubricator and feeding the tire into the test station, a controller grasps a position of the barcode on the tire based on a rotation angle relative to the direction connecting a position where the barcode is detected by a barcode scanner and the center of the tire.

Abstract: In a rim replacing method for a tire testing machine of the present invention, one pair of the rims satisfying predetermined conditions relative to a test tire are selected, from among a pair of rims attached to the upper and lower spindles and plural pairs of rims loaded in a rim replacing device, as object rims, and rim replacement is performed if the rims loaded in the rim replacing device are selected as the object rims, so that the nonuniformity of rim can be suitably measured. The predetermined conditions include a condition in which a diameter of bead portions of the tire conveyed into the tire testing machine corresponds to a diameter of the object rims, and a condition in which a width of the bead portions of the tire conveyed into the tire testing machine falls within a range in which a space between the object rims is adjustable.

Abstract: A tire testing machine includes a test station in which spindles to attach a tire on which a barcode is installed are provided, and first and second belt conveyors that feed the tire into a center position of the spindles. In order to stably grasp a position of identifying information of the tire and stop rotation of the tire at an arbitrary desired angle, before applying a lubricant to a bead portion on an inner periphery of the tire conveyed to the first belt conveyors by means of the lubricator and feeding the tire into the test station, a controller grasps a position of the barcode on the tire based on a rotation angle relative to the direction connecting a position where the barcode is detected by a barcode scanner and the center of the tire.

Abstract: The present invention provides a reagent and a method of safely, conveniently, and specifically diagnosing Crohn's disease. Provided are a diagnostic method for Crohn's disease in a subject, including measuring antibodies against one kind or more of dietary components selected from the group consisting of grapefruit, alfalfa, avocado, cabbage, green pepper, lettuce, onion, potato (white), spinach, tomato, oat, pecan, yeast, cane sugar, celery, buckwheat, corn, rice and soy, and a diagnostic reagent or kit for Crohn's disease, containing the above-mentioned preparation of a dietary component.

Abstract: Each gene in a group comprising many genes is cloned into an expression vector so that its gene product should be expressed as a fusion protein with a protein emitting self-fluorescence to construct a gene expression library. The gene expression library is introduced into cells of two groups to express the fusion proteins in the cells, and only one cell group is stimulated by a drug or the like. Then, cells in which the fusion proteins are localized in the nuclei or their nuclei are isolated from cells of the two groups, respectively. By comparing these cells, genes coding for proteins that are transported into the nuclei specifically in response to a certain stimulus when the stimulus is applied to the cells are retrieved.

Abstract: A gene panel comprising a group of genes of which expression levels change in hepatocytes during liver regeneration as compared with those in a normal state is produced by the following steps: (a) the step of measuring expression levels of various genes in hepatocytes of a model animal in a normal state and expression levels of the genes during liver regeneration; (b) the step of comparing the expression levels, respectively; and (c) the step of identifying a group of genes of which expression levels change during liver regeneration.

Abstract: The present invention provides a pharmaceutical agent (e.g., a therapeutic agent) for treatment of mitochondrial disorders, which is highly safe with minimal adverse effects. Thus, the pharmaceutical agent is extremely useful as a medical product for mitochondrial disorders. The present invention also provides a method for preventing, ameliorating and/or therapeutically treating mitochondrial disorders by administering the pharmaceutical agent of the present invention.

Abstract: Each gene in a group comprising many genes is cloned into an expression vector so that its gene product should be expressed as a fusion protein with a protein emitting self-fluorescence to construct a gene expression library. The gene expression library is introduced into cells of two groups to express the fusion proteins in the cells, and only one cell group is stimulated by a drug or the like. Then, cells in which the fusion proteins are localized in the nuclei or their nuclei are isolated from cells of the two groups, respectively. By comparing these cells, genes coding for proteins that are transported into the nuclei specifically in response to a certain stimulus when the stimulus is applied to the cells are retrieved.

Abstract: A method for producing xylitol by allowing a microorganism belonging to the Gluconobacter oxydans or Acetobacter xylinum and having a D-arabitol dehydrogenase activity and a D-xylulose reductase (xylitol dehydrogenase) activity and an ability to convert D-arabitol to xylitol is acted on D-arabitol in a reaction mixture containing a carbon source to produce xylitol.