Patents by Inventor Maili LIU

Maili LIU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11959982
    Abstract: A low-cost modular liquid nitrogen low-temperature multi-nuclear magnetic resonance probe includes a Dewar, a pluggable coil and a front-end gain amplifier. The Dewar includes a cylindrical sandwich chamber, the center of the cylindrical sandwich chamber constitutes a room-temperature chamber, a sandwich of the cylindrical sandwich chamber is divided into a vacuum chamber and a liquid nitrogen chamber by a liquid nitrogen vessel wall, the vacuum chamber is located between the room-temperature chamber and the liquid nitrogen chamber, the pluggable coil and the front-end gain amplifier are provided in the vacuum chamber, the pluggable coil comprises a coil portion and a pluggable base, the coil portion is in pluggable connection with the pluggable base, and the pluggable coil is connected with the front-end gain amplifier. The probe realizes the transmission of radio frequency pulses and the reception of magnetic resonance signals, and is applicable to whole-body imaging of a small animal.
    Type: Grant
    Filed: November 10, 2021
    Date of Patent: April 16, 2024
    Assignee: INNOVATION ACADEMY FOR PRECISION MEASUREMENT SCIENCE AND TECHNOLOGY, CAS
    Inventors: Zhi Zhang, Qingjia Bao, Chaoyang Liu, Xinjie Liu, Fang Chen, Jiaxin Wang, Xin Cheng, Maili Liu
  • Publication number: 20240085502
    Abstract: A low-cost modular liquid nitrogen low-temperature multi-nuclear magnetic resonance probe includes a Dewar, a pluggable coil and a front-end gain amplifier. The Dewar includes a cylindrical sandwich chamber, the center of the cylindrical sandwich chamber constitutes a room-temperature chamber, a sandwich of the cylindrical sandwich chamber is divided into a vacuum chamber and a liquid nitrogen chamber by a liquid nitrogen vessel wall, the vacuum chamber is located between the room-temperature chamber and the liquid nitrogen chamber, the pluggable coil and the front-end gain amplifier are provided in the vacuum chamber, the pluggable coil comprises a coil portion and a pluggable base, the coil portion is in pluggable connection with the pluggable base, and the pluggable coil is connected with the front-end gain amplifier. The probe realizes the transmission of radio frequency pulses and the reception of magnetic resonance signals, and is applicable to whole-body imaging of a small animal.
    Type: Application
    Filed: November 10, 2021
    Publication date: March 14, 2024
    Applicant: INNOVATION ACADEMY FOR PRECISION MEASUREMENT SCIENCE AND TECHNOLOGY, CAS
    Inventors: Zhi ZHANG, Qingjia BAO, Chaoyang LIU, Xinjie LIU, Fang CHEN, Jiaxin WANG, Xin CHENG, Maili LIU
  • Patent number: 10795171
    Abstract: An optical-fiber atomic light-filtering apparatus comprising an optical-fiber coupling focusing collimating mirror, a first polarizing optical fiber, a first permanent magnetic ring, a pure iron frame shaped like the Chinese character “”, a heat preservation box, a first capillary atomic cell, an armored twisted-pair heating wire, a second permanent magnetic ring, a second polarizing optical fiber, a thermostat, a cable, a third permanent magnetic ring, a temperature sensor, a second capillary atomic cell, a fourth permanent magnetic ring, a third polarizing optical fiber and a photoelectric detector. The two pairs of permanent magnetic rings are matched with the pure iron frame shaped like the Chinese character “” to provide magnetic fields for the two capillary atomic cells working in the same temperature environment; a polarizing plane changes after interaction between a weak signal light and atoms.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: October 6, 2020
    Assignee: Wuhan Institute of Physics And Mathematics Chinese Academy of Sciences
    Inventors: Xin Zhou, Xianping Sun, Xiuchao Zhao, Maili Liu, Chaohui Ye
  • Patent number: 10705169
    Abstract: An inert gas nucleus channel device comprising a magnetic resonance control system, a radio frequency generator, an RF amplifier and AD converter, a frequency synthesizer, a first mixer, a second power amplifier, a second T/R switch, an inert gas nucleus coil, a second pre-amplifier and a second mixer. A magnetic resonance imaging method is also disclosed. The method controls an increase or decrease in a frequency of a pulse or echo signal excited by a radio-frequency signal, implementing magnetic resonance imaging using hyperpolarized inert gases (such as xenon, helium, and krypton), making it possible to apply MRI to lungs and brains using the hyperpolarized inert gases, and expanding the probing range of MRI. The inert gas nucleus channel device is simple in structure and easy to operate and upgrades a hydrogen nucleus magnetic resonance imaging instrument to become a multi-nuclei MRI system using the hyperpolarized inert gases.
    Type: Grant
    Filed: August 8, 2018
    Date of Patent: July 7, 2020
    Assignee: Wuhan Institute of Physics And Mathematics, Chinese Academy of Sciences
    Inventors: Xin Zhou, Yeqing Han, Xianping Sun, Lei Shi, Maili Liu, Chaohui Ye
  • Publication number: 20190121152
    Abstract: An optical-fiber atomic light-filtering apparatus comprising an optical-fiber coupling focusing collimating mirror, a first polarizing optical fiber, a first permanent magnetic ring, a pure iron frame shaped like the Chinese character “”, a heat preservation box, a first capillary atomic cell, an armored twisted-pair heating wire, a second permanent magnetic ring, a second polarizing optical fiber, a thermostat, a cable, a third permanent magnetic ring, a temperature sensor, a second capillary atomic cell, a fourth permanent magnetic ring, a third polarizing optical fiber and a photoelectric detector. The two pairs of permanent magnetic rings are matched with the pure iron frame shaped like the Chinese character “” to provide magnetic fields for the two capillary atomic cells working in the same temperature environment; a polarizing plane changes after interaction between a weak signal light and atoms.
    Type: Application
    Filed: December 13, 2018
    Publication date: April 25, 2019
    Inventors: Xin ZHOU, Xianping SUN, Xiuchao ZHAO, Maili LIU, Chaohui YE
  • Publication number: 20180372823
    Abstract: An inert gas nucleus channel device comprising a magnetic resonance control system, a radio frequency generator, an RF amplifier and AD converter, a frequency synthesizer, a first mixer, a second power amplifier, a second T/R switch, an inert gas nucleus coil, a second pre-amplifier and a second mixer. A magnetic resonance imaging method is also disclosed. The method controls an increase or decrease in a frequency of a pulse or echo signal excited by a radio-frequency signal, implementing magnetic resonance imaging using hyperpolarized inert gases (such as xenon, helium, and krypton), making it possible to apply MRI to lungs and brains using the hyperpolarized inert gases, and expanding the probing range of MRI. The inert gas nucleus channel device is simple in structure and easy to operate and upgrades a hydrogen nucleus magnetic resonance imaging instrument to become a multi-nuclei MRI system using the hyperpolarized inert gases.
    Type: Application
    Filed: August 8, 2018
    Publication date: December 27, 2018
    Inventors: Xin ZHOU, Yeqing HAN, Xianping SUN, Lei SHI, Maili LIU, Chaohui YE