Patents by Inventor Maja Oktay

Maja Oktay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NEOADJUVANT CHEMOTHERAPY INDUCES BREAST CANCER METASTASIS THROUGH A TMEM-MEDIATED MECHANISM
    Publication number: 20240019439
    Abstract: Methods of reducing chemotherapy-induced metastasis, or chemotherapy-induced cancer cell dissemination, for patients subject to chemotherapy using Tie-2 inhibitors. Methods of reducing chemotherapy-induced metastasis, or chemotherapy-induced cancer cell dissemination, for patients subject to chemotherapy using inhibitors of Mena expression and/or function are also provided.
    Type: Application
    Filed: September 13, 2023
    Publication date: January 18, 2024
    Inventors: John S. Condeelis, Maja Oktay
  • Method for treating neoadjuvant chemotherapy-induced metastasis
    Patent number: 11802875
    Abstract: Methods of reducing chemotherapy-induced metastasis, or chemotherapy-induced cancer cell dissemination, for patients subject to chemotherapy using Tie-2 inhibitors. Methods of reducing chemotherapy-induced metastasis, or chemotherapy-induced cancer cell dissemination, for patients subject to chemotherapy using inhibitors of Mena expression and/or function are also provided.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: October 31, 2023
    Inventors: John S. Condeelis, Maja Oktay
  • TMEM-MCD IN THE MINIMALLY INVASIVE ASSESSMENT OF THE ACTIVITY STATUS OF TMEM IN ITS DISSEMINATION OF TUMOR CELLS
    Publication number: 20210244830
    Abstract: Methods are provided for measuring the activity of TMEM sites in a tumor comprising measuring a transient increase in permeability of blood vessels at TMEM sites that allows tumor cells to enter the blood vessels, wherein permeability is measured using a modality selected from the group consisting of MRI, PET, CT, and SPECT, and wherein a transient increase in permeability indicates that a TMEM site is active. The method can include, for example, obtaining a MenaINV score assessed by fine needle aspiration in the same tissue. The present invention can be used as both a prognostic for dissemination and a predictive end point for identification and validation of dissemination inhibitors/anti-metastasis drugs.
    Type: Application
    Filed: June 12, 2019
    Publication date: August 12, 2021
    Inventors: John CONDEELIS, Craig BRANCH, Maja OKTAY
  • METHOD FOR TREATING NEOADJUVANT CHEMOTHERAPY-INDUCED METASTASIS
    Publication number: 20210156861
    Abstract: Methods of reducing chemotherapy-induced metastasis, or chemotherapy-induced cancer cell dissemination, for patients subject to chemotherapy using Tie-2 inhibitors. Methods of reducing chemotherapy-induced metastasis, or chemotherapy-induced cancer cell dissemination, for patients subject to chemotherapy using inhibitors of Mena expression and/or function are also provided.
    Type: Application
    Filed: May 30, 2018
    Publication date: May 27, 2021
    Inventors: John S. Condeelis, Maja Oktay