Patents by Inventor Majella Maher

Majella Maher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • eIF2? gene as a diagnostic target for the identification of fungal and yeast species
    Patent number: 9944996
    Abstract: The current invention relates to a diagnostic kit for a yeast or fungal species comprising at least one oligonucleotide probe capable of binding to at least a portion of the eIF2y gene or its corresponding mRNA.
    Type: Grant
    Filed: June 15, 2009
    Date of Patent: April 17, 2018
    Assignee: National University of Ireland, Galway
    Inventors: Thomas Gerard Barry, Majella Maher, Terry James Smith, Marcin Jankiewicz, Louise O'Connor, Nina Tuite, Sinead Lahiff
  • SWI5 gene as a diagnostic target for the identification of fungal and yeast species
    Patent number: 9745636
    Abstract: The invention relates to the SWI5 gene, the corresponding RNA, specific probes, primers and oligonucleotides related thereto and their use in diagnostic assays to detect and/or discriminate between fungal and yeast species.
    Type: Grant
    Filed: June 15, 2009
    Date of Patent: August 29, 2017
    Assignee: National University of Ireland, Galway
    Inventors: Thomas Gerard Barry, Majella Maher, Terry James Smith, Marcin Jankiewicz, Louise O'Connor, Nina Tuite, Sinead Lahiff
  • Nucleic acids probes for detection of yeast and fungal
    Patent number: 9458514
    Abstract: The present invention use of to a portion of the RPS7 gene or its corresponding mRNA in a diagnostic assay for fungal and yeast species and sequences for use in such assays and methods.
    Type: Grant
    Filed: December 14, 2007
    Date of Patent: October 4, 2016
    Assignee: National University of Ireland, Galway
    Inventors: Thomas Gerard Barry, Terence James Smith, Majella Maher
  • A/Guf1 gene sequences as a diagnostic target for the identification of bacterial species
    Patent number: 9243298
    Abstract: The current invention relates to a diagnostic kit for a bacterial species and/or fungal and/or yeast species comprising at least one oligonucleotide probe capable of binding to at least a portion of the LepA and/or Guf1 genes or its corresponding mRNA.
    Type: Grant
    Filed: June 15, 2009
    Date of Patent: January 26, 2016
    Assignee: National University of Ireland, Galway
    Inventors: Thomas Gerard Barry, Majella Maher, Terence James Smith, Justin O'Grady
  • ACE2 AS A TARGET GENE FOR THE MOLECULAR IDENTIFICATION OF YEAST AND FUNGAL SPECIES
    Publication number: 20120094283
    Abstract: The present invention relates to nucleic acid primers and probes for use in the identification of one or more yeast species. More specifically the invention relates to the Ace2 gene, the corresponding RNA, specific probes, primers and oligonucleotides related thereto and their use in diagnostic assays to detect and/or discriminate between yeast species.
    Type: Application
    Filed: June 15, 2009
    Publication date: April 19, 2012
    Inventors: Thomas Gerard Barry, Terry James Smith, Majella Maher, Marcin Jankiewicz, Louise O'Connor, Nina Tuite, Sinead Lahiff
  • Diagnostic Kit for Aspergillus Fumigatus Species
    Publication number: 20110311969
    Abstract: The use of the Ayg1 gene or an RNA transcript of the Ayg1 gene or fragments thereof as target regions in a diagnostic assay for the eukaryotic organism Aspergillus fumigatus species is described. The unique sequence of the Ayg1 gene in Aspergillus fumigatus provides the basis of nucleic acid diagnostic test for the identification of the pathogen at a the molecular level.
    Type: Application
    Filed: July 10, 2009
    Publication date: December 22, 2011
    Applicant: NATIONAL UNIVERSITY OF IRELAND, GALWAY
    Inventors: Louise O'Connor, Majella Maher
  • Method for detecting C. albicans
    Patent number: 8029987
    Abstract: A HWP1 gene sequence or fragment or variants thereof as a target region in a nucleic acid based assay for Candida albicans and an isolated nucleic acid molecule useful as a probe for identifying C. albicans in a sample. A method for the detection of C. albicans in a sample and quantification of HWP1 gene expression in C. albicans is also described.
    Type: Grant
    Filed: April 13, 2006
    Date of Patent: October 4, 2011
    Assignee: National University of Ireland, Galway
    Inventors: Louise O'Connor, Majella Maher
  • EIF2GAMMA GENE AS A DIAGNOSTIC TARGET FOR THE IDENTIFICATION OF FUNGAL AND YEAST SPECIES
    Publication number: 20110218335
    Abstract: The current invention relates to a diagnostic kit for a yeast or fungal species comprising at least one oligonucleotide probe capable of binding to at least a portion of the eIF2y gene or its corresponding mRNA.
    Type: Application
    Filed: June 15, 2009
    Publication date: September 8, 2011
    Inventors: Thomas Gerard Barry, Majella Maher, Terry James Smith, Marcin Jankiewicz, Louise O'Connor, Nina Tuite, Sinead Lahiff
  • P2/P2A/P2B GENE SEQUENCES AS DIAGNOSTIC TARGETS FOR THE IDENTIFICATION OF FUNGAL AND YEAST SPECIES
    Publication number: 20110217703
    Abstract: The present invention relates to nucleic acid primers and probes to detect one or more fungal and yeast species. More specifically the invention relates to the P2, P2A and P2B gene sequences (also known as 60S acidic ribosomal protein P2, RLA-2-ASPFU, Allergen ASP f8 or Afp2), the corresponding RNA, specific probes, primers and oligonucleotides related thereto and their use in diagnostic assays to detect and/or discriminate fungal and yeast species.
    Type: Application
    Filed: June 15, 2009
    Publication date: September 8, 2011
    Inventors: Thomas Gerard Barry, Terry James Smith, Marcin Jankiewicz, Louise O'Connor, Nina Tuite, Sinead Lahiff, Majella Maher
  • LEPA/GUF1 GENE SEQUENCES AS A DIAGNOSTIC TARGET FOR THE IDENTIFICATION OF BACTERIAL SPECIES
    Publication number: 20110217704
    Abstract: The current invention relates to a diagnostic kit for a bacterial species and/or fungal and/or yeast species comprising at least one oligonucleotide probe capable of binding to at least a portion of the LepA and/or Guf1 genes or its corresponding mRNA.
    Type: Application
    Filed: June 15, 2009
    Publication date: September 8, 2011
    Inventors: Thomas Gerard Barry, Majella Maher, Terence James Smith, Justin O'Grady
  • SWI5 GENE AS A DIAGNOSTIC TARGET FOR THE IDENTIFICATION OF FUNGAL AND YEAST SPECIES
    Publication number: 20110212445
    Abstract: The invention relates to the SWI5 gene, the corresponding RNA, specific probes, primers and oligonucleotides related thereto and their use in diagnostic assays to detect and/or discriminate between fungal and yeast species.
    Type: Application
    Filed: June 15, 2009
    Publication date: September 1, 2011
    Inventors: Thomas Gerard Barry, Majella Maher, Terry James Smith, Marcin Jankiewicz, Louise O'Connor, Nina Tuite, Sinead Lahiff
  • Nucleic acid probes and methods for detecting clinically important fungal pathogens
    Patent number: 7741461
    Abstract: The current invention relates to the field of detection and identification of clinically important fungi. More particularly, the present invention relates to species specific probes originating from the Internal Transcribed Spacer (ITS) region of rDNA for the detection of fungal species such as Candida albicans, Candida parapsilosis, Candida tropicalis, Candida kefyr, Candida krusei, Candida glabrata, Candida dubliniensis, Aspergillus flavus, Aspergillus versicolor, Aspergillus nidulans, Aspergillus fumigatus, Cryptococcus neoformans and Pneumocystis carinii in clinical samples, and methods using said probes.
    Type: Grant
    Filed: October 19, 2004
    Date of Patent: June 22, 2010
    Assignees: Innogenetics N.V., Enterprise Ireland, National University of Ireland Galway
    Inventors: Terry Smith, Majella Maher, Cara Martin, Geert Jannes, Rudi Rossau, Marjo Van der Weide
  • NUCLEIC ACIDS PROBES FOR DETECTION OF YEAST AND FUNGAL SPECIES
    Publication number: 20100143910
    Abstract: The present invention use of to a portion of the RPS7 gene or its corresponding mRNA in a diagnostic assay for fungal and yeast species and sequences for use in such assays and methods.
    Type: Application
    Filed: December 14, 2007
    Publication date: June 10, 2010
    Applicant: NATIONAL UNIVERSITY OF IRELAND, GALWAY
    Inventors: Thomas Gerard Barry, Terance James Smith, Majella Maher
  • METHOD FOR DETECTING C. ALBICANS
    Publication number: 20090208940
    Abstract: A HWP1 gene sequence or fragment or variants thereof as a target region in a nucleic acid based assay for Candida albicans and an isolated nucleic acid molecule useful as a probe for identifying C. albicans in a sample. A method for the detection of C. albicans in a sample and quantification of HWP1 gene expression in C. albicans is also described.
    Type: Application
    Filed: April 13, 2006
    Publication date: August 20, 2009
    Inventors: Louise O'Connor, Majella Maher
  • Nucleic acid probes and methods for detecting clinically important fungal pathogens
    Publication number: 20050164243
    Abstract: The current invention relates to the field of detection and identification of clinically important fungi. More particularely, the present invention relates to species specific probes originating from the Internal Transcribed Spacer (ITS) region of rDNA for the detection of fungal species such as Candida albicans, Candida parapsilosis, Candida tropicalis, Candida kefyr, Candida krusei, Candida glabrata, Candida dubliniensis, Aspergillus flavus, Aspergillus versicolor, Aspergillus nidulans, Aspergillus fumigatus, Cryptococcus neoformans and Pneumocystis carinii in clinical samples, and methods using said probes.
    Type: Application
    Filed: October 19, 2004
    Publication date: July 28, 2005
    Inventors: Terry Smith, Majella Maher, Cara Martin, Geert Jannes, Rudi Rossau, Marjo Van der Weide
  • Nucleic acid probes and methods for detecting clinically important fungal pathogens
    Patent number: 6858387
    Abstract: The current invention relates to the field of detection and identification of clinically important fungi. More particularely, the present invention relates to species specific probes originating from the Internal Transcribed Spacer (ITS) region of rDNA for the detection of fungal species such as Candida albicans, Candida parapsilosis, Candida tropicalis, Candida kefyr, Candida krusei, Candida glabrata, Candida dubliniensis, Aspergillus flavus, Aspergillus versicolor, Aspergillus nidulans, Aspergillus fumigatus, Cyptococcus neoformans and Pneumocystis carinii in clinical samples, and methods using said probes.
    Type: Grant
    Filed: September 15, 2000
    Date of Patent: February 22, 2005
    Assignees: Innogenetics, N.V., Enterprise Ireland
    Inventors: Terry Smith, Majella Maher, Cara Martin, Geert Jannes, Rudi Rossau, Marjo Van Der Weide