Patents by Inventor Makarand Krishnakumar Avachat
Makarand Krishnakumar Avachat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200171124Abstract: The invention relates to topical compositions of lipoglycopeptides. The compositions may additionally contain one or more non-steroidal anti-inflammatory agents. The compositions are used to treat ophthalmic or otic conditions.Type: ApplicationFiled: April 13, 2017Publication date: June 4, 2020Inventors: Sajeev Chandran, Ashok Bhagwat Nighute, Makarand Krishnakumar Avachat
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Patent number: 10058569Abstract: The invention relates to stable oral pharmaceutical compositions comprising lanthanum carbonate compounds and pharmaceutically acceptable excipients. The compositions of the present invention are formulated without the use of flow aids or lubricants. The compositions of the present invention have physical properties & flowability indicators comparable to that of the powders containing flow aids or lubricants and these compositions can be filled in sachets without any difficulty.Type: GrantFiled: June 23, 2016Date of Patent: August 28, 2018Assignee: LUPIN LIMITEDInventors: Makarand Krishnakumar Avachat, Nikhil P. Malewar, Anirudha B. Kute, Girish Purushottam Bang
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Publication number: 20180116952Abstract: A solid pharmaceutical oral composition for once or twice daily administration is provided. The composition includes pulsed release pellets. Each pellet includes at least a first drug layer comprising methylergonovine or a pharmaceutically acceptable salt thereof, and a second drug layer comprising methylergonovine or a pharmaceutically acceptable salt thereof. The solid pharmaceutical oral composition includes from about 0.3 mg to about 0.8 mg in total of methylergonovine or a pharmaceutically acceptable salt thereof. The composition is used for treating a subject having a methylergonovine responsive condition such as migraine, refractory migraine, uterine atony, uterine haemorrhage, subinvolution of the uterus, and uterine haemorrhage in the second stage of labor.Type: ApplicationFiled: November 22, 2017Publication date: May 3, 2018Applicant: LUPIN ATLANTIS HOLDINGS SAInventors: James Allen Garegnani, Makarand Krishnakumar Avachat, Sajeev Chandran, Ashish Ashokrao Deshmukh, Ganesh Bhaskarrao Shete
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Publication number: 20180116953Abstract: A solid pharmaceutical oral composition once or twice daily administration is provided. The composition includes an immediate release core comprising methylergonovine or a pharmaceutically acceptable salt thereof, and a polymer coating disposed on the immediate release core. The composition comprises from about 0.3 mg to about 0.8 mg in total of methylergonovine or a pharmaceutically acceptable salt thereof. The composition is used for treating a subject having a methylergonovine responsive condition such as migraine, refractory migraine, uterine atony, uterine haemorrhage, subinvolution of the uterus, and uterine haemorrhage in the second stage of labor.Type: ApplicationFiled: November 22, 2017Publication date: May 3, 2018Applicant: Lupin Atlantis Holdings SAInventors: James Allen Garegnani, Makarand Krishnakumar Avachat, Sajeev Chandran, Ashish Ashokrao Deshmukh, Ganesh Bhaskarrao Shete
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Publication number: 20180098982Abstract: A solid pharmaceutical oral composition for once daily administration is provided. The composition includes from about 0.5 mg to about 0.8 mg in total of methylergonovine or a pharmaceutically acceptable salt thereof. The composition is used for treating a subject having a methylergonovine responsive condition such as migraine, refractory migraine, uterine atony, uterine haemorrhage, subinvolution of the uterus, and uterine haemorrhage in the second stage of labor.Type: ApplicationFiled: November 22, 2017Publication date: April 12, 2018Applicant: LUPIN ATLANTIS HOLDINGS SAInventors: James Allen Garegnani, Makarand Krishnakumar Avachat, Sajeev Chandran, Ashish Ashokrao Deshmukh, Ganesh Bhaskarrao Shete
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Publication number: 20180098942Abstract: A solid pharmaceutical oral composition for twice daily administration is provided. The composition includes from about 0.3 mg to about 0.6 mg in total of methylergonovine or a pharmaceutically acceptable salt thereof. The composition is used for treating a subject having a methylergonovine responsive condition such as migraine, refractory migraine, uterine atony, uterine haemorrhage, subinvolution of the uterus, and uterine haemorrhage in the second stage of labor.Type: ApplicationFiled: November 22, 2017Publication date: April 12, 2018Applicant: Lupin Atlantis Holdings SAInventors: James Allen Garegnani, Makarand Krishnakumar Avachat, Sajeev Chandran, Ashish Ashokrao Deshmukh, Ganesh Bhaskarrao Shete
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Publication number: 20160375055Abstract: The invention relates to stable oral pharmaceutical compositions comprising lanthanum carbonate compounds and pharmaceutically acceptable excipients. The compositions of the present invention are formulated without the use of flow aids or lubricants. The compositions of the present invention have physical properties & flowability indicators comparable to that of the powders containing flow aids or lubricants and these compositions can be filled in sachets without any difficulty.Type: ApplicationFiled: June 23, 2016Publication date: December 29, 2016Inventors: Makarand Krishnakumar AVACHAT, Nikhil P. MALEWAR, Anirudha B. KUTE, Girish Purushottam BANG
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Patent number: 9241905Abstract: A pharmaceutical suspension formulation comprising a dose greater than 100 mg/5 ml Cefixime and pharmaceutically acceptable excipients.Type: GrantFiled: March 23, 2007Date of Patent: January 26, 2016Assignee: LUPIN LIMITEDInventors: Sanjay Chhagan Wagh, Bharat Raghunath Metkar, Makarand Krishnakumar Avachat, Himadri Sen
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Patent number: 9233112Abstract: A pharmaceutical suspension dosage form comprising greater than 80 mg/ml and not more than 150 mg/ml of Cefixime and pharmaceutically acceptable excipients.Type: GrantFiled: June 8, 2011Date of Patent: January 12, 2016Assignee: LUPIN LIMITEDInventors: Shrenik Annasaheb Kole, Bharat Raghunath Metkar, Makarand Krishnakumar Avachat
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Patent number: 9028865Abstract: A controlled release pharmaceutical composition which comprises therapeutically effective amount of pregabalin or salts thereof as active ingredient, a hydrophobic release controlling agent(s) and optionally other pharmaceutically acceptable excipients thereof.Type: GrantFiled: May 31, 2013Date of Patent: May 12, 2015Assignee: Lupin LimitedInventors: Rahul Manorajan Sammohi, Nikhil Prabhakar Malewar, Makarand Krishnakumar Avachat
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Patent number: 8900637Abstract: A stable taste masked, pharmaceutical composition comprising a plurality of coated, non-disintegrating discrete dosage units, said units comprising of a core comprising one or more cephalosporins such as cefuroxime axetil and cefpodoxime proxetil and one or more coating layers. Cefuroxime axetil is in ?-crystalline and amorphous forms, where at least 30% of the Cefuroxime axetil is in the ?-crystalline form, wherein the particle size distribution of the ?-crystalline form being such that 100% of the particles have a particle size below 250?. The ratio of the crystalline fraction to the amorphous fraction ranges from 0.3:0.7 to 0.99:0.01. The particle size of cefpodoxime proxetil is such that 90% of the particles are below 15?.Type: GrantFiled: December 2, 2005Date of Patent: December 2, 2014Assignee: Lupin LimitedInventors: Sachin Pundlik Kolhe, Subrata Kundu, Sanjay Chhagan Wagh, Makarand Krishnakumar Avachat, Himadri Sen
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Patent number: 8785432Abstract: A single layer pharmaceutical composition comprising active agent(s) amlodipine or a pharmaceutically acceptable salt thereof and valsartan or a pharmaceutically acceptable salt thereof wherein the composition exhibits bioequivalence to the commercially available bilayer tablet dosage form comprising amlodipine besylate and valsartan; when administered to human subject, under the bioequivalence parameters of a 90% Confidence Interval for AUC which is between 80% and 125%, and a 90% Confidence Interval for Cmax, which is between 80% and 125%.Type: GrantFiled: February 21, 2008Date of Patent: July 22, 2014Assignee: Lupin LimitedInventors: Anirudha Bhagirath Kute, Nikhil Prabhakar Malewar, Makarand Krishnakumar Avachat
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Publication number: 20130261184Abstract: A controlled release pharmaceutical composition which comprises therapeutically effective amount of pregabalin or salts thereof as active ingredient, a hydrophobic release controlling agent(s) and optionally other pharmaceutically acceptable excipients thereof.Type: ApplicationFiled: May 31, 2013Publication date: October 3, 2013Inventors: Rahul Manorajan Sammohi, Nikhil Prabhakar Malewar, Makarand Krishnakumar Avachat
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Patent number: 8454993Abstract: A controlled release pharmaceutical composition which comprises therapeutically effective amount of pregabalin or salts thereof as active ingredient, a hydrophobic release controlling agent(s) and optionally other pharmaceutically acceptable excipients thereof.Type: GrantFiled: November 14, 2008Date of Patent: June 4, 2013Assignee: Lupin LimitedInventors: Rahul Manorajan Sammohi, Nikhil Prabhakar Malewar, Makarand Krishnakumar Avachat
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Publication number: 20110301139Abstract: A pharmaceutical suspension dosage form comprising greater than 80 mg/ml and not more than 150 mg/ml of Cefixime and pharmaceutically acceptable excipients.Type: ApplicationFiled: June 8, 2011Publication date: December 8, 2011Applicant: Lupin LimitedInventors: Shrenik Annasaheb KOLE, Bharat Raghunath Metkar, Makarand Krishnakumar Avachat
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Publication number: 20110123609Abstract: A multiple unit dosage form useful for treating or preventing hyperlipidemia and/or atherosclerosis, wherein multiple unit dosage form comprise of a therapeutically effective amount of niacin or its derivatives and one or more control releasing agent(s) and pharmaceutically acceptable excipients, weight percentages are based upon the total weight of the dosage form. The multiple unit dosage form may comprise of optionally other antihyperlipidemic agent, more preferably HMG CoA reductase inhibitor. The most preferable dosage form is capsule. Further a kit comprising one or more capsules co-packaged to provide multiple unit dosage form of niacin or its derivatives in combination with HMG CoA reductase inhibitor is disclosed.Type: ApplicationFiled: July 16, 2009Publication date: May 26, 2011Inventors: Sunil Shantwan Borude, Shrenik Annasaheb Kole, Makarand Krishnakumar Avachat
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Publication number: 20110020439Abstract: A delayed release dosage form comprising core comprising duloxetine or its pharmaceutically acceptable salts or derivatives thereof, optionally, other pharmaceutically acceptable excipient(s) thereof; intermediate layer; and enteric layer; wherein the dosage form comprises one/more dissolution enhancer(s), wherein the enteric layer comprises one/more enteric polymers other than hydroxypropylmethyl acetate succinate. A process of preparing a delayed release dosage comprising mixing pharmaceutically acceptable excipients with duloxetine or its pharmaceutically acceptable derivatives thereof; granulating the product of previous step compressing the granulate formed in previous step to form core, coating said core with intermediate layer followed by coating with one/more enteric polymers and optional finishing coating.Type: ApplicationFiled: March 17, 2009Publication date: January 27, 2011Inventors: Shrenik Annasaheb Kole, Ashok Kumar Sahoo, Makarand Krishnakumar Avachat
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Publication number: 20100272801Abstract: A single layer pharmaceutical composition comprising active agent(s) amlodipine or a pharmaceutically acceptable salt thereof and valsartan or a pharmaceutically acceptable salt thereof wherein the composition exhibits bioequivalence to the commercially available bilayer tablet dosage form comprising amlodipine besylate and valsartan; when administered to human subject, under the bioequivalence parameters of a 90% Confidence Interval for AUC which is between 80% and 125%, and a 90% Confidence Interval for Cmax, which is between 80% and 125%.Type: ApplicationFiled: February 21, 2008Publication date: October 28, 2010Applicant: Lupin LimitedInventors: Anirudha Bhagirath Kute, Nikhil Prabhakar, Makarand Krishnakumar Avachat
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Publication number: 20100255067Abstract: A controlled release pharmaceutical composition which comprises therapeutically effective amount of pregabalin or salts thereof as active ingredient, a hydrophobic release controlling agent(s) and optionally other pharmaceutically acceptable excipients thereof.Type: ApplicationFiled: November 14, 2008Publication date: October 7, 2010Applicant: LUPIN LIMITEDInventors: Rahul Manorajan Sammohi, Nikhil Prabhakar Malewar, Makarand Krishnakumar Avachat
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Publication number: 20100009955Abstract: A pharmaceutical suspension formulation comprising a dose greater than 100 mg/5 ml Cefixime and pharmaceutically acceptable excipients.Type: ApplicationFiled: March 23, 2007Publication date: January 14, 2010Applicant: Lupin LimitedInventors: Sanjay Chhagan Wagh, Bharat Raghunath Metkar, Makarand Krishnakumar Avachat, Himadri Sen