Patents by Inventor Maki Kayama

Maki Kayama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10617735
    Abstract: Provided are methods and compositions for maintaining the viability of retinal ganglion cells in a subject with an ocular disorder including, for example, glaucoma and optic nerve injury. The viability of the retinal ganglion cells can be preserved by administering a necrosis inhibitor either alone or in combination with an apoptosis inhibitor to a subject having an eye with the ocular condition. The compositions, when administered, maintain the viability of the cells and/or promote axon regeneration, thereby minimizing the loss of vision or visual function associated with the ocular disorder.
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: April 14, 2020
    Assignee: Massachusetts Eye and Ear Infirmary
    Inventors: Demetrios G. Vavvas, Joan W. Miller, Maki Kayama
  • Publication number: 20190099467
    Abstract: Provided are methods and compositions for maintaining the viability of retinal ganglion cells in a subject with an ocular disorder including, for example, glaucoma and optic nerve injury. The viability of the retinal ganglion cells can be preserved by administering a necrosis inhibitor either alone or in combination with an apoptosis inhibitor to a subject having an eye with the ocular condition. The compositions, when administered, maintain the viability of the cells and/or promote axon regeneration, thereby minimizing the loss of vision or visual function associated with the ocular disorder.
    Type: Application
    Filed: April 18, 2018
    Publication date: April 4, 2019
    Inventors: Demetrios G. Vavvas, Joan W. Miller, Maki Kayama
  • Patent number: 9993517
    Abstract: Provided are methods and compositions for maintaining the viability of retinal ganglion cells in a subject with an ocular disorder including, for example, glaucoma and optic nerve injury. The viability of the retinal ganglion cells can be preserved by administering a necrosis inhibitor either alone or in combination with an apoptosis inhibitor to a subject having an eye with the ocular condition. The compositions, when administered, maintain the viability of the cells and/or promote axon regeneration, thereby minimizing the loss of vision or visual function associated with the ocular disorder.
    Type: Grant
    Filed: April 7, 2016
    Date of Patent: June 12, 2018
    Assignee: Massachusetts Eye and Ear Infirmary
    Inventors: Demetrios G. Vavvas, Joan W. Miller, Maki Kayama
  • Publication number: 20160367619
    Abstract: Provided are methods and compositions for maintaining the viability of retinal ganglion cells in a subject with an ocular disorder including, for example, glaucoma and optic nerve injury. The viability of the retinal ganglion cells can be preserved by administering a necrosis inhibitor either alone or in combination with an apoptosis inhibitor to a subject having an eye with the ocular condition. The compositions, when administered, maintain the viability of the cells and/or promote axon regeneration, thereby minimizing the loss of vision or visual function associated with the ocular disorder.
    Type: Application
    Filed: April 7, 2016
    Publication date: December 22, 2016
    Inventors: Demetrios G. Vavvas, Joan W. Miller, Maki Kayama
  • Publication number: 20140024598
    Abstract: Provided are methods and compositions for maintaining the viability of retinal ganglion cells in a subject with an ocular disorder including, for example, glaucoma and optic nerve injury. The viability of the retinal ganglion cells can be preserved by administering a necrosis inhibitor either alone or in combination with an apoptosis inhibitor to a subject having an eye with the ocular condition. The compositions, when administered, maintain the viability of the cells and/or promote axon regeneration, thereby minimizing the loss of vision or visual function associated with the ocular disorder.
    Type: Application
    Filed: October 21, 2011
    Publication date: January 23, 2014
    Inventors: Demetrios Vavvas, Joan W. Miller, Maki Kayama