Patents by Inventor Makio Furuichi
Makio Furuichi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9783807Abstract: A nucleic acid molecule utilizable for Salmonella detection is provided. The nucleic acid molecule which binds to Salmonella includes any of the following polynucleotides (a) to (d): (a) a polynucleotide composed of any of base sequences of SEQ ID NOs: 1 to 17; (b) a polynucleotide composed of a base sequence obtained by deletion, substitution, insertion, and/or addition of one or more bases in any of the base sequences in the polynucleotide (a) and is bound to Salmonella; (c) a polynucleotide composed of a base sequence having an identity of 80% or more to any of the base sequences in the polynucleotide (a) and is bound to Salmonella; and (d) a polynucleotide composed of a base sequence complementary to a polynucleotide which hybridizes to the polynucleotide (a) composed of any of the base sequences under stringent conditions and is bound to Salmonella.Type: GrantFiled: November 6, 2013Date of Patent: October 10, 2017Assignee: NEC SOLUTION INNOVATORS, LTD.Inventors: Hirotaka Minagawa, Jou Akitomi, Naoto Kaneko, Makio Furuichi, Katsunori Horii, Iwao Waga
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Patent number: 9689025Abstract: The technique by which simple analysis of an intended subject to be analyzed can be carried out is provided. In this technique, a nucleic acid element 16 for use in analysis including: a first nucleic acid part 12; and a second nucleic acid part 13 is used. In the nucleic acid element 16, the first nucleic acid part 12 is a binding part that can bind to a subject 11 to be analyzed, and the second nucleic acid part 13 is a labeling part that can distinguish between binding and non-binding of the first nucleic acid part 12 to the subject 11. It is preferred that the first nucleic acid part 12 is an aptamer against the subject 11. The subject 11 can be analyzed easily by using the nucleic acid element 16, binding the subject 11 to the first nucleic acid part 12, and then analyzing the binding with the second nucleic acid part 13.Type: GrantFiled: August 6, 2010Date of Patent: June 27, 2017Assignee: NEC Solution Innovators, Ltd.Inventors: Iwao Waga, Jou Akitomi, Makio Furuichi
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Patent number: 9557339Abstract: The present invention is to provide a nucleic acid molecule having a binding affinity to a rodent-derived IgG antibody, which can be prepared easier than an antibody and has a binding affinity equivalent or superior to that of an antibody, a binder using the nucleic acid molecule, a detection reagent, and a detection kit. The nucleic acid molecule of the present invention has a binding affinity to a rodent-derived IgG antibody and has a dissociation constant of 1 ?M or less. The binder for a rodent-derived IgG antibody of the present invention includes the nucleic acid molecule of the present invention. The detection reagent for detecting a rodent-derived IgG antibody of the present invention includes the binder for a rodent-derived IgG antibody of the present invention. The detection kit for detecting a rodent-derived IgG antibody of the present invention includes the detection reagent for detecting a rodent-derived IgG antibody of the present invention.Type: GrantFiled: July 21, 2014Date of Patent: January 31, 2017Assignee: NEC Solution Innovators, Ltd.Inventors: Hiromi Takenaka, Yoshihito Yoshida, Katsunori Horii, Makio Furuichi, Hirotaka Yagi, Jou Akitomi, Mineko Yamaguchi, Shintarou Katou, Kensaku Nishikata, Iwao Waga
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Publication number: 20160169875Abstract: The present invention is to provide a new sensor for melamine detection. The nucleic acid sensor for melamine analysis of the present invention includes a polynucleotide (x1) that includes a catalytic nucleic acid molecule (D) that activates a catalytic function and a binding nucleic acid molecule (A) that binds to melamine. The polynucleotide (x1) has any one of the base sequences of SEQ ID NOs: 1 to 14, and n and m are positive integers. In the nucleic acid sensor, since the catalytic function of the catalytic nucleic acid molecule (D) is inhibited in the absence of melamine and the catalytic function of the catalytic nucleic acid molecule (D) is activated in the presence of melamine, melamine can be analyzed by detecting the catalytic function.Type: ApplicationFiled: July 23, 2013Publication date: June 16, 2016Inventors: Katsunori Horii, Naoto Kaneko, Jou Akitomi, Shintarou Katou, Makio Furuichi, Iwao Waga
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Publication number: 20150299709Abstract: A nucleic acid molecule utilizable for Salmonella detection is provided. The nucleic acid molecule which binds to Salmonella includes any of the following polynucleotides (a) to (d): (a) a polynucleotide composed of any of base sequences of SEQ ID NOs: 1 to 17; (b) a polynucleotide composed of a base sequence obtained by deletion, substitution, insertion, and/or addition of one or more bases in any of the base sequences in the polynucleotide (a) and is bound to Salmonella; (c) a polynucleotide composed of a base sequence having an identity of 80% or more to any of the base sequences in the polynucleotide (a) and is bound to Salmonella; and (d) a polynucleotide composed of a base sequence complementary to a polynucleotide which hybridizes to the polynucleotide (a) composed of any of the base sequences under stringent conditions and is bound to Salmonella.Type: ApplicationFiled: November 6, 2013Publication date: October 22, 2015Inventors: Hirotaka Minagawa, Jou Akitomi, Naoto Kaneko, Makio Furuichi, Katsunori Horii, lwao Waga
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Publication number: 20150167106Abstract: The present invention provides a nucleic acid molecule applicable to detection of influenza virus. The nucleic acid molecule according to the present invention is a nucleic acid molecule that binds to an influenza virus, including at least one polynucleotide selected from the group consisting of the following polynucleotides (a) to (d): (a) a polynucleotide that has any of base sequences of SEQ ID NOs: 1 to 30; (b) a polynucleotide that has a base sequence obtained by deletion, substitution, insertion, and/or addition of one or more bases in any of the base sequences of the polynucleotide (a) and binds to the influenza virus; (c) a polynucleotide that has a base sequence with an identity of at least 80% to any of the base sequences of the polynucleotide (a) and binds to the influenza virus; and (d) a polynucleotide that has a base sequence complementary to a polynucleotide hybridizing to any of the base sequences of the polynucleotide (a) under stringent conditions and binds to the influenza virus.Type: ApplicationFiled: April 25, 2013Publication date: June 18, 2015Applicant: NEC Solution Innovators, Ltd.Inventors: Ikuo Shiratori, Jou Akitomi, Katsunori Horii, Makio Furuichi, Iwao Waga
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Publication number: 20140370618Abstract: The present invention is to provide a nucleic acid molecule having a binding affinity to a rodent-derived IgG antibody, which can be prepared easier than an antibody and has a binding affinity equivalent or superior to that of an antibody, a binder using the nucleic acid molecule, a detection reagent, and a detection kit. The nucleic acid molecule of the present invention has a binding affinity to a rodent-derived IgG antibody and has a dissociation constant of 1 ?M or less. The binder for a rodent-derived IgG antibody of the present invention includes the nucleic acid molecule of the present invention. The detection reagent for detecting a rodent-derived IgG antibody of the present invention includes the binder for a rodent-derived IgG antibody of the present invention. The detection kit for detecting a rodent-derived IgG antibody of the present invention includes the detection reagent for detecting a rodent-derived IgG antibody of the present invention.Type: ApplicationFiled: July 21, 2014Publication date: December 18, 2014Applicant: NEC SOFT, LTD.Inventors: Hiromi TAKENAKA, Yoshihito YOSHIDA, Katsunori HORII, Makio FURUICHI, Hirotaka YAGI, Jou AKITOMI, Mineko YAMAGUCHI, Shintarou KATOU, Kensaku NISHIKATA, Iwao WAGA
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Patent number: 8852954Abstract: The invention provides a nucleic acid molecule having a binding affinity to a rodent-derived IgG antibody, which can be prepared easier than an antibody and has a binding affinity equivalent or superior to that of an antibody, a binder using the nucleic acid molecule, a detection reagent, and a detection kit. The nucleic acid molecule of the invention has a binding affinity to a rodent-derived IgG antibody and has a dissociation constant of 1 ?M or less. The binder for a rodent-derived IgG antibody of the present invention includes the nucleic acid molecule of the present invention. The detection reagent for detecting a rodent-derived IgG antibody of the invention includes the binder for a rodent-derived IgG antibody of the invention. The detection kit for detecting a rodent-derived IgG antibody of the invention includes the detection reagent for detecting a rodent-derived IgG antibody of the invention.Type: GrantFiled: August 21, 2009Date of Patent: October 7, 2014Assignee: NEC Solution Innovators, Ltd.Inventors: Hiromi Takenaka, Yoshihito Yoshida, Katsunori Horii, Makio Furuichi, Hirotaka Yagi, Jou Akitomi, Mineko Yamaguchi, Shintarou Katou, Kensaku Nishikata, Iwao Waga
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Publication number: 20130022967Abstract: The invention provides a nucleic acid molecule having a binding affinity to a rodent-derived IgG antibody, which can be prepared easier than an antibody and has a binding affinity equivalent or superior to that of an antibody, a binder using the nucleic acid molecule, a detection reagent, and a detection kit. The nucleic acid molecule of the invention has a binding affinity to a rodent-derived IgG antibody and has a dissociation constant of 1 ?M or less. The binder for a rodent-derived IgG antibody of the present invention includes the nucleic acid molecule of the present invention. The detection reagent for detecting a rodent-derived IgG antibody of the invention includes the binder for a rodent-derived IgG antibody of the invention. The detection kit for detecting a rodent-derived IgG antibody of the invention includes the detection reagent for detecting a rodent-derived IgG antibody of the invention.Type: ApplicationFiled: August 21, 2009Publication date: January 24, 2013Applicant: NEC SOFT, LTD.Inventors: Hiromi Takenaka, Yoshihito Yoshida, Katsunori Horii, Makio Furuichi, Hirotaka Yagi, Jou Akitomi, Mineko Yamaguchi, Shintarou Katou, Kensaku Nishikata, Iwao Waga
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Patent number: 8283457Abstract: The present invention provides a nucleic acid molecule having an ability to bind to a rabbit anti-mouse IgG antibody, which can be prepared more easily than an antibody and has a binding ability equal to or higher than that of an antibody. The nucleic acid molecule according to the present invention may have the sequences set forth in SEQ ID NOS: 1 to 5. The nucleic acid molecule according to the present invention may be a nucleic acid having an ability to bind to a rabbit IgG antibody, which substantially has homology to its sequence. The nucleic acid molecule according to the present invention may have a binding constant (KD) of 1.18×10?7 (M) or less to the rabbit IgG antibody.Type: GrantFiled: November 22, 2007Date of Patent: October 9, 2012Assignee: NEC Soft, Ltd.Inventors: Yoshihito Yoshida, Makio Furuichi, Iwao Waga, Hiroshi Mizuno
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Publication number: 20120202195Abstract: The technique by which simple analysis of an intended subject to be analyzed can be carried out is provided. In this technique, a nucleic acid element 16 for use in analysis including: a first nucleic acid part 12; and a second nucleic acid part 13 is used. In the nucleic acid element 16, the first nucleic acid part 12 is a binding part that can bind to a subject 11 to be analyzed, and the second nucleic acid part 13 is a labeling part that can distinguish between binding and non-binding of the first nucleic acid part 12 to the subject 11. It is preferred that the first nucleic acid part 12 is an aptamer against the subject 11. The subject 11 can be analyzed easily by using the nucleic acid element 16, binding the subject 11 to the first nucleic acid part 12, and then analyzing the binding with the second nucleic acid part 13.Type: ApplicationFiled: August 6, 2010Publication date: August 9, 2012Applicant: NEC SOFT, LTD.Inventors: Iwao Waga, Jou Akitomi, Makio Furuichi
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Publication number: 20120003749Abstract: The present invention relates to a nucleic acid molecule capable of binding to a 2,4,6-trinitrophenyl skeleton, a method for detecting a compound having the 2,4,6-trinitrophenyl skeleton using the nucleic acid molecule, use of the nucleic acid molecule for detecting a compound having the 2,4,6-trinitrophenyl skeleton, and a method for detecting a compound having the 2,4,6-trinitrophenyl skeleton.Type: ApplicationFiled: May 12, 2009Publication date: January 5, 2012Applicant: NEC SOFT, LTD.Inventors: Yoshihito Yoshida, Katsunori Horii, Jou Akitomi, Makio Furuichi, Iwao Waga
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Publication number: 20100222559Abstract: The present invention provides a nucleic acid molecule having an ability to bind to a rabbit anti-mouse IgG antibody, which can be prepared more easily than an antibody and has a binding ability equal to or higher than that of an antibody. The nucleic acid molecule according to the present invention may have the sequences set forth in SEQ ID NOS: 1 to 5. The nucleic acid molecule according to the present invention may be a nucleic acid having an ability to bind to a rabbit IgG antibody, which substantially has homology to its sequence. The nucleic acid molecule according to the present invention may have a binding constant (KD) of 1.18×10?7 (M) or less to the rabbit IgG antibody.Type: ApplicationFiled: November 22, 2007Publication date: September 2, 2010Inventors: Yoshihito Yoshida, Makio Furuichi, Iwao Waga, Hiroshi Mizuno
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Publication number: 20100129870Abstract: The present invention is to provide a method for obtaining an oligonucleotide such as RNA aptamer having high binding capacity to a target substance with easy-to-use and high purity. The method for obtaining oligonucleotide according to the present invention is as follows: A method for obtaining oligonucleotide comprising the steps of: performing an electrophoresis of a nucleic acid molecule/target substance complex comprising a nucleic acid molecule and a target substance; recovering said nucleic acid molecule/target substance complex; extracting the nucleic acid molecule from said nucleic acid molecule/target substance complex; gene amplifying said nucleic acid molecule.Type: ApplicationFiled: July 10, 2007Publication date: May 27, 2010Applicants: NEC Soft, Ltd., National Institute of Advanced Industrial Science and TechnologyInventors: Fumiko Nishikawa, Satoshi Nishikawa, Makio Furuichi, Hiroshi Mizuno, Iwao Waga