Patents by Inventor Makobetsa Abel Khati

Makobetsa Abel Khati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CD7 receptor aptamers
    Patent number: 9422563
    Abstract: Nucleic acid aptamers which bind specifically to or are internalised into cells expressing a CD7 cell-surface receptor are disclosed. The aptamers comprise a nucleic acid molecule having a sequence which is at least 80% identical to 5?-GG-GAGACAAGAAUAAGCAUG-R1-UUCGACAGGAGGCUCACAACAGnynz-3? (SEQ ID NO: 3). The aptamers can be linked to therapeutic or diagnostic molecules, and can be used to deliver the therapeutic or diagnostic molecules to cells expressing the CD7 receptor. The aptamers can also be used as detection tools.
    Type: Grant
    Filed: March 18, 2014
    Date of Patent: August 23, 2016
    Assignee: University of the Witwatersrand, Johannesburg
    Inventors: Laura Ann Millroy, Makobetsa Abel Khati, Mark Saul Weinberg
  • CD7 Receptor Aptamers
    Publication number: 20160032291
    Abstract: Nucleic acid aptamers which bind specifically to or are internalised into cells expressing a CD7 cell-surface receptor are disclosed. The aptamers comprise a nucleic acid molecule having a sequence which is at least 80% identical to 5?-GG-GAGACAAGAAUAAGCAUG-R1-UUCGACAGGAGGCUCACAACAGnynz-3? (SEQ ID NO: 3). The aptamers can be linked to therapeutic or diagnostic molecules, and can be used to deliver the therapeutic or diagnostic molecules to cells expressing the CD7 receptor. The aptamers can also be used as detection tools.
    Type: Application
    Filed: March 18, 2014
    Publication date: February 4, 2016
    Inventors: Laura Ann Millroy, Makobetsa Abel Khati, Mark Saul Weinberg