Abstract: The present invention provides a compound which has the effect of PDE inhibition, and which is useful as a medicament for preventing or treating schizophrenia or so on. A compound of formula (I0): wherein R1 represents a substituent, R2 represents a hydrogen atom, or a substituent, R3 represents a hydrogen atom, or a substituent, Ring A represents an aromatic ring which can be substituted, and Ring B represents a 5-membered heteroaromatic ring which can be substituted, or a salt thereof.

Abstract: Provided is a compound having a PDE10A inhibitory action, and useful as a medicament for the prophylaxis or treatment of mental diseases such as schizophrenia and the like, and the like. A compound represented by the formula (I): wherein each symbol is as defined in the DESCRIPTION, or a salt thereof.

Abstract: The present invention provides a compound which has the effect of PDE inhibition, and which is useful as a medicament for preventing or treating schizophrenia or so on. A compound of formula (I0), wherein R1 represents a substituent; R2 represents a hydrogen atom, or a substituent; R3 represents a hydrogen atom, or a substituent; Ring A represents an aromatic ring which can be substituted, and Ring B represents a 5-membered heteroaromatic ring which can be substituted, or a salt thereof.

Abstract: The present invention provides a compound represented by the formula (1): wherein each symbol is as defined in the specification, or a salt thereof, a prodrug of the compound or a salt thereof, a medicament containing the compound or a salt thereof, the medicament which is a phosphodiesterase 10A inhibitor, and a medicament which is for preventing or treating schizophrenia.

Abstract: The present invention aims to provide a compound having a PDE inhibitory action and useful as a medicament for the prophylaxis or treatment of schizophrenia and the like. A compound represented by the formula (1x): wherein each symbol is as described in the DESCRIPTION, or the formula (1): W1—W2??(1) wherein each symbol is as described in the DESCRIPTION, or a salt thereof.

Abstract: Provided is a compound having a PDE10A inhibitory action, and useful as a medicament for the prophylaxis or treatment of mental diseases such as schizophrenia and the like, and the like. A compound represented by the formula (I): wherein each symbol is as defined in the DESCRIPTION, or a salt thereof.

Abstract: The present invention provides a compound which has the effect of PDE inhibition, and which is useful as a medicament for preventing or treating schizophrenia or so on. A compound of formula (I0), wherein R1 represents a substituent; R2 represents a hydrogen atom, or a substituent; R3 represents a hydrogen atom, or a substituent; Ring A represents an aromatic ring which can be substituted, and Ring B represents a 5-membered heteroaromatic ring which can be substituted, or a salt thereof.

Abstract: The present invention provides a compound which has the effect of PDE inhibition, and which is useful as a medicament for preventing or treating schizophrenia or so on. A compound of formula (I0), wherein R1 represents a substituent; R2 represents a hydrogen atom, or a substituent; R3 represents a hydrogen atom, or a substituent; Ring A represents an aromatic ring which can be substituted, and Ring B represents a 5-membered heteroaromatic ring which can be substituted, or a salt thereof.

Abstract: The present invention provides a compound which has the effect of PDE inhibition, and which is useful as a medicament for preventing or treating schizophrenia or so on. A compound of formula (I0): wherein R1 represents a substituent, R2 represents a hydrogen atom, or a substituent, R3 represents a hydrogen atom, or a substituent, Ring A represents an aromatic ring which can be substituted, and Ring B represents a 5-membered heteroaromatic ring which can be substituted, or a salt thereof.

Abstract: In a route selection process, an optimal route searcher 5 refers to a traffic light flag included in route selecting data stored in a second storage 4 to see whether a target intersection has any traffic light or not. When the optimal route searcher 5 determines that the target intersection has a traffic light s, a traffic light cost calculator 6 calculates a traffic light cost relevant to a waiting time due to the traffic light s. Based on the traffic light cost thus calculated by the traffic light cost calculator 6, the optimal route searcher 5 calculates a passage cost relevant to a time taken for passing the target intersection. In this manner, with consideration for the waiting time due to the traffic light, a time for going through an entire route can be estimated with higher correctness, thereby rendering the route thus searched more optimal.

Abstract: In areas where composite intersection traffic regulation exits, nodes and links for use in the conventional network are separated into a plurality of nodes and links, respectively. For example, one node is separated into N1a to N1c, and one link is separated into L1a to L1c. Then, the whole road network is represented by separating the network into a road network (L1a, L2a, L3a, L4a, L5a, N1a, N2a) in view of entering links (L1a, L3a) which the composite intersection traffic regulation does not affect, and road networks .alpha. (L1b, L2b, L3b, L4b, N1b, N2b) and .beta. (L1c, L2c, L3c, L5c, N1c, N2c) in view of entering links (L4b, L5c) which the composite intersection traffic regulation affects, and one-way traffic regulations are set on suitable links to allow for a representation of the composite intersection transfer regulation.

Abstract: A route selection data storage unit 7 stores route selection data which are created from original data describing a detailed road system. When a plurality of crossings and a plurality of roads which are expressed on the road system in the original data satisfy prescribed conditions, these crossings and roads are integrated with each other respectively and recorded in the route selection data. The route selection data include a passage link table, so that links which are deleted by integration of the crossings are not missed. The passage link table records links which are deleted due to the integration of the crossings but passed in practice with reference to approach and escape links as to the respective crossings integrated with each other. An optimum route search unit 6 searches for the optimum route between a starting place and a destination which are designated by a position detection unit and/or a spot input unit 5 through the route selection data.

Abstract: An optimum route searching device 5 conducts a search in a predetermined area on road network data on a lower hierarchical level to obtain minimum arrival costs to individual nodes in the search area and then selects a node located on an upper hierarchical level existing in from the search area. Then the optimum route searching device 5 obtains a remaining cost to a node common with the upper hierarchical level which first appears on the upper hierarchical level existing link. Then the optimum route searching device 5 obtains a minimum arrival cost from the starting point of the search to the common node on the basis of the minimum arrival cost to the selected node and the remaining cost to the common node. The minimum arrival cost to the common node obtained at this time is used as initial conditions for a route search performed on the road network data on the upper hierarchical level.

Abstract: The present invention involves road network recording device for recording positions and connection relation of intersection and roads, location setting device for setting departure point and destination point, search start and endpoint setting device for setting a plurality of search start points or search end points, by using a specific range on a map on the basis of the departure point or destination point set by the location setting device, search device for searching a recommended route from the search start point to the search end point set by the search start and end, point setting device from the information in the road network recording device according to a specific rule, and output device for putting out the route obtained by the search device.