Abstract: A method monitors an air-conditioner having a semi-conductor gas sensor, the method including: determining that a refrigerant leakage has occurred on condition that the detection value is equal to or greater than a first threshold when the fan is in operation; starting operation of the fan as a provisional operation if the detection value is equal to or greater than a second threshold when the fan is not in operation; stopping the provisional operation of the fan; determining that a refrigerant leakage has occurred on condition that the detection value is equal to or greater than a third threshold after stopping the provisional operation of the fan; and taking a predetermined action for outputting alarm information and/or limiting supply of refrigerant to the heat exchanger when a refrigerant leakage is determined to have occurred.

Abstract: A filter includes first and second signal terminals, a filter circuit connected between the first and second signal terminals, a substrate having first and second surfaces, the first and second signal terminals being located on the first surface, a part of the filter circuit being located at a side of the second surface, a line located closer to the first surface than the filter circuit in the substrate, a first end of the line being connected to one of the first and second signal terminals, and a ground terminal that is located on the first surface and to which a second end of the line is connected, an area of a region where the line overlaps with the ground terminal being greater than an area of a region where the line overlaps with the one of the first and second signal terminals when the substrate is viewed in plan view.

Abstract: The purpose of the present technology is to provide a technique for accurately determining cognitive impairment, cognitive decline, or risk of any of them. The present technology provides a determination supporting information generating method, comprising: an index value calculating step of calculating, based on amounts of two or more biomarkers contained in a biological sample derived from a human, (I) a first index value indicating the presence or absence of cognitive impairment or cognitive decline in the human and (II) a second index value indicating the degree of progression of cognitive impairment or cognitive decline in the human; and a supporting information generating step of generating information that supports determination of cognitive impairment, cognitive decline, or risk of any of them, based on the first index value and the second index value.

Abstract: A filter includes an input terminal, an output terminal, a ground terminal, a first capacitor and a second capacitor that are connected in series between the input terminal and the output terminal, a capacitive element that is connected in parallel to the first capacitor and the second capacitor between the input terminal and the output terminal, and has a Q factor that is smaller than a Q factor of the first capacitor and is smaller than a Q factor of the second capacitor, and an inductor that has a first end and a second end, the first end being coupled to a node that is provided between the first capacitor and the second capacitor and that is coupled to the capacitive element through the first capacitor and the second capacitor, the second end being coupled to the ground terminal.

Abstract: A filter includes an input terminal, an output terminal, a first ground terminal, a second ground terminal, a first inductor having a first end coupled to a first node in a path between the input terminal and the output terminal and a second end coupled to a second node, a second inductor having a first end coupled to the second node and a second end coupled to the first ground terminal, and a third inductor having a first end coupled to the second node and a second end coupled to the second ground terminal.

Abstract: A refrigeration system includes a first device, a second device communicably connected to the first device via a first cable and a second cable, and a refrigerant pipe configured to cause refrigerant circulation to the first device or the second device, in which the first device includes a first circuit configured to short-circuit the first cable and the second cable upon detection of abnormality relevant to refrigerant leakage, and the second device includes a second circuit configured to start protection behavior against abnormality when the first cable and the second cable are short-circuited.

Abstract: A method monitors an air-conditioner having a semi-conductor gas sensor, the method including: determining that a refrigerant leakage has occurred on condition that the detection value is equal to or greater than a first threshold when the fan is in operation; starting operation of the fan as a provisional operation if the detection value is equal to or greater than a second threshold when the fan is not in operation; stopping the provisional operation of the fan; determining that a refrigerant leakage has occurred on condition that the detection value is equal to or greater than a third threshold after stopping the provisional operation of the fan; and taking a predetermined action for outputting alarm information and/or limiting supply of refrigerant to the heat exchanger when a refrigerant leakage is determined to have occurred.

Abstract: A refrigerant cycle apparatus includes a refrigerant circuit that circulates a refrigerant, and a leak sensor that detects a refrigerant leaking from the refrigerant circuit, in which the refrigerant cycle apparatus includes, as an operating mode, a recovery mode for recognizing occurrence of an abnormality in the leak sensor and recovering a refrigerant to a predetermined location in the refrigerant circuit.

Abstract: Provided is a method for manufacturing a sheet for use in a tongue plaque cleaner, capable of reliably cutting loops of thread members provided at a given density, and forming thread members each having a shape with an arc portion sufficient enough to scrape off tongue plaque, through steps that are simple, low-cost and suitable for mass production. A method for manufacturing a sheet 1 for use in a tongue plaque cleaner for scraping off tongue plaque, includes: a step of heating a sheet material having multiple looped thread members 2 protruding from one surface of the sheet material, at a temperature below the melting point of the thread members 2; and a step of forming first thread members 3, 8 and second thread members 4, 9 by cutting loops of the thread members 2 heated.

Abstract: A filter includes an input terminal, an output terminal, a first ground terminal, a second ground terminal, a first inductor having a first end coupled to a first node in a path between the input terminal and the output terminal and a second end coupled to a second node, a second inductor having a first end coupled to the second node and a second end coupled to the first ground terminal, and a third inductor having a first end coupled to the second node and a second end coupled to the second ground terminal.

Abstract: A filter includes an input terminal, an output terminal, a ground terminal, a first capacitor and a second capacitor that are connected in series between the input terminal and the output terminal, a capacitive element that is connected in parallel to the first capacitor and the second capacitor between the input terminal and the output terminal, and has a Q factor that is smaller than a Q factor of the first capacitor and is smaller than a Q factor of the second capacitor, and an inductor that has a first end and a second end, the first end being coupled to a node that is provided between the first capacitor and the second capacitor and that is coupled to the capacitive element through the first capacitor and the second capacitor, the second end being coupled to the ground terminal.

Abstract: A high-frequency device includes: a circuit substrate including dielectric layers that are stacked, wiring patterns located on at least one of the dielectric layers, and a passive element formed of at least one of the wiring patterns, the circuit substrate having a first surface that is a surface of an outermost dielectric layer in a stacking direction of the dielectric layers; a terminal for connecting the high-frequency device to an external circuit, the terminal being located on the first surface and electrically connected to the passive element through a first path in the circuit substrate; and an acoustic wave element located on the first surface and electrically connected to the passive element through a second path in the circuit substrate.

Abstract: In this invention, a non-infectious particle has been produced, comprising a pathogen antigen protein caused to be expressed on the surface of a virus particle having at least one species of paramyxovirus envelope protein missing from the particle. This particle has been found to hold within the particle a large amount of antigen protein compared to an infectious particle, and to be capable of eliciting a host immune response with extremely high efficiency. The non-infectious particle according to the present invention is useful as a vaccine against a pathogenic virus, or the like.

Abstract: A filter includes first and second signal terminals, a filter circuit connected between the first and second signal terminals, a substrate having first and second surfaces, the first and second signal terminals being located on the first surface, a part of the filter circuit being located at a side of the second surface, a line located closer to the first surface than the filter circuit in the substrate, a first end of the line being connected to one of the first and second signal terminals, and a ground terminal that is located on the first surface and to which a second end of the line is connected, an area of a region where the line overlaps with the ground terminal being greater than an area of a region where the line overlaps with the one of the first and second signal terminals when the substrate is viewed in plan view.

Abstract: A filter includes: a substrate; input and output terminals located on the substrate; a resonant circuit located in a series pathway between the input and output terminals; a first component including a first inductor, which is electrically connected between a first node in the series pathway and a ground, and mounted in a first region on the substrate; a second component including a second inductor, which is electrically connected between a second node different from the first node in the series pathway and a ground, and mounted in a second region different from the first region on the substrate; and a third component including an acoustic wave resonator, which is electrically connected between a third node between the first and second nodes in the series pathway and a ground, and mounted in a third region between the first and second regions on the substrate.

Abstract: Provided is a nerve cell production method including preparing stem cells, and introducing Sendai virus by infection to the stem cells to induce the stem cells into nerve cells by allowing the Sendai virus to express mRNA which synthesizes an inducing factor in the stem cells.

Abstract: A semiconductor device is provided which can detect a fluctuation of a power supply voltage. The semiconductor device includes a counter circuit that outputs a signal when a period during which a power supply voltage of a system to be monitored is lower than or equal to a first voltage value exceeds a predetermined time, a first flag circuit that sets a first flag based on the signal, a second flag circuit that sets a second flag when the power supply voltage becomes a second voltage value or lower, and a circuit that outputs a reset signal that resets the system when both the first and the second flags are set. The first voltage value and the second voltage value are higher than a minimum voltage that guarantees normal operation of the system. The first voltage value is higher than the second voltage value.

Abstract: The present invention provides polypeptides for selectively inducing target antigen-specific CD8-positive T-cell responses. Since induction of human immunodeficiency virus (HIV)-specific CD4-positive T-cell responses by vaccine could promote HIV infection, an HIV vaccine antigen that selectively induces HIV-specific CD8-positive T-cell responses would be useful if obtained. Thus, in the present invention, polypeptide antigens were designed in which 8- to 12-residue amino acid sequences divided from the amino acid sequence of a target antigen protein were connected in an order different from that of the original amino acid sequence. DNA and viral vector vaccines expressing these antigens were tested by inoculation into monkeys. As a result, they were shown to be able to efficiently induce antigen-specific CD8-positive T-cell responses in a selective manner. The instant antigens may be useful as vaccine antigens that induce CD8-positive T cells in a highly selective manner.

Abstract: The present invention relates to a vector(s) containing and expressing an optimized HIV EnvF gene, methods for making the same and cell substrates qualified for vaccine production which may comprise vector(s) containing optimized HIV genes.

Abstract: An objective of the present invention is to provide an improved negative-strand RNA viral vector and a use thereof, the negative-strand RNA viral vector exhibiting transient high expression of genes loaded in the vector and enabling the rapid removal of the vector after said expression. It was discovered that by adding a micro-RNA target sequence to the NP, P, or L gene of a negative-strand RNA viral vector, it is possible to control the expression of the vector depending on the micro-RNA expressed by the introduction cell. In particular, when a micro-RNA target sequence was added to the NP or P gene, the expression of the vector decreased depending on the micro-RNA, and the removal of the vector was promoted, while the effect was reversed when a micro-RNA target sequence was added to the L gene. The vector can be applied in cell therapy and regenerative medicine and can be used as a therapeutic vector that targets cancer.