Abstract: Some embodiments of a micro-fluidic device include at least one inlet hole located on an inlet side of the microfluidic device, the inlet hole consisting of a plurality of holes with diameters smaller in size than a diameter of the at least one inlet hole, at least one outlet hole located on an outlet side of the microfluidic device opposite the inlet side; and a micro-channel, where the plurality of holes are connected to the micro-channel.

Abstract: The present invention relates to sample-to-answer systems, devices, cartridges, and method of using the same for detecting the presence of microorganisms in a sample, such as bacteria.

Abstract: The present disclosure relates in general to a diagnostic device for inspection of an enclosed tube system, and more particular, to obtain images or video of the interior of the enclosed tube system while the diagnostic device is attached to a moveable member and traveling through the enclosed tube system. A diagnostic apparatus including camera housing configured to include a camera assembly, battery housing configured to hold a battery assembly, and a main housing configured to be detachably secured to a moveable member, wherein the camera housing and battery assembly are secured to the main housing, and wherein the main housing includes at least one light.

Abstract: Some embodiments of a micro-fluidic device include at least one inlet hole located on an inlet side of the microfluidic device, the inlet hole consisting of a plurality of holes with diameters smaller in size than a diameter of the at least one inlet hole, at least one outlet hole located on an outlet side of the microfluidic device opposite the inlet side; and a micro-channel, where the plurality of holes are connected to the micro-channel

Abstract: The present disclosure relates in general to a diagnostic device for inspection of an enclosed tube system, and more particular, to obtain images or video of the interior of the enclosed tube system while the diagnostic device is attached to a moveable member and traveling through the enclosed tube system. A diagnostic apparatus including camera housing configured to include a camera assembly, battery housing configured to hold a battery assembly, and a main housing configured to be detachably secured to a moveable member, wherein the camera housing and battery assembly are secured to the main housing, and wherein the main housing includes at least one light.

Abstract: The present invention relates to systems and methods for preparing a fluidic cartridge for use in an analyzer device. In one non-limiting aspect, the present invention provides a method of preparing a fluidic cartridge for use in an analyzer device. The method may include controlling valves and a vacuum pump of a priming station to evacuate air from a fluidic cartridge loaded in the priming station. The method may include controlling the valves and the vacuum pump to draw priming fluid into sipper wells and channels of the loaded fluidic cartridge. In another non-limiting aspect, the present invention provides a priming station for preparing a fluidic cartridge for use in an analyzer device. The priming station may include a vacuum pump, a priming manifold assembly, and a controller. The priming manifold assembly may be configured to interface with a fluidic cartridge loaded in the priming station.

Abstract: The present invention relates to sample-to-answer systems, devices, cartridges, and method of using the same for detecting the presence of microorganisms in a sample, such as bacteria.

Abstract: The present invention provides a flow-channel device for detecting light emission, which suppresses a noise originating in unnecessary light emission, and can be simply bonded with the use of an organic material. The flow-channel device having a flow channel is structured by the bonding of at least two substrates, wherein at least any one substrate has a first groove which constitutes the flow channel, and a second groove for arranging an adhesive therein which contains an organic material, and a light-shielding layer is provided on an inner wall of the second groove so as to block a light emitted from the second groove from penetrating into the first groove.

Abstract: A real time analysis in accordance with temperature change and highly sensitive detection are permitted. A flow passage device has a flow passage (1) and is able to heat a fluid in the flow passage. A state of the fluid in the flow passage is observable using light. The flow passage device includes a first member (2) including an observation surface (3) and an upper inner wall surface (4), and a second member (5) including a lower inner wall surface that opposes the upper inner wall surface (4) and that is part of inner walls of the flow passage. A heating resistor (6) having a reflective surface that reflects light is provided on the lower inner wall surface. The light reflected by the reflective surface passes through the upper inner wall surface (4) and the observation surface (3).

Abstract: A light emission detection device having a flow path from which light to be detected is emitted is provided. The device includes a detection-side substrate having a joining surface and a detection surface provided opposite the joining surface, the joining surface having a depression and a light-shielding film provided over an area excluding the depression, the depression forming the flow path, the detection surface transmitting the light emitted from the flow path; and a wiring-side substrate having a joining surface and a conductive pattern provided with a varying thickness on the joining surface, the joining surface of the wiring-side substrate joining the joining surface of the detection-side substrate. In the area over which the light-shielding film is provided, adhesive is provided with a thickness corresponding to the varying thickness of the conductive pattern and the detection-side substrate and the wiring-side substrate are closely joined to each other with the adhesive.

Abstract: A liquid measuring unit includes a first capillary tube, a second capillary tube, and a holding portion that holds the first capillary tube and the second capillary tube, wherein a distance between a liquid contact portion of the first capillary tube and the holding portion is longer than a distance between a liquid contact portion of the second capillary tube and the holding portion.

Abstract: In order to position components each including a channel in assembly, provided are a positioning method, which is particularly useful in manufacturing a component using an injection molding technology, and a device to which the method is applicable. Specifically, provided is a channel device, including: a first device including a channel; and a second device including a channel, the channel device being formed by joining the first device and the second device to each other so that the channel in the first device and the channel in the second device communicate to each other, the first device having a plurality of holes along an outer side of an edge of a region of the first device, which is joined to the second device.

Abstract: Provided is a heating device, including: a first heating region including a first material; and a second heating region including a second material, the second heating region having a smaller temperature coefficient of resistance than a temperature coefficient of resistance of the first heating region, the first heating region and the second heating region being connected to each other.

Abstract: A real time analysis in accordance with temperature change and highly sensitive detection are permitted. A flow passage device has a flow passage (1) and is able to heat a fluid in the flow passage. A state of the fluid in the flow passage is observable using light. The flow passage device includes a first member (2) including an observation surface (3) and an upper inner wall surface (4), and a second member (5) including a lower inner wall surface that opposes the upper inner wall surface (4) and that is part of inner walls of the flow passage. A heating resistor (6) having a reflective surface that reflects light is provided on the lower inner wall surface. The light reflected by the reflective surface passes through the upper inner wall surface (4) and the observation surface (3).

Abstract: The present invention provides a flow-channel device for detecting light emission, which suppresses a noise originating in unnecessary light emission, and can be simply bonded with the use of an organic material. The flow-channel device having a flow channel is structured by the bonding of at least two substrates, wherein at least any one substrate has a first groove which constitutes the flow channel, and a second groove for arranging an adhesive therein which contains an organic material, and a light-shielding layer is provided on an inner wall of the second groove so as to block a light emitted from the second groove from penetrating into the first groove.

Abstract: A light emission detection device having a flow path from which light to be detected is emitted is provided. The device includes a detection-side substrate having a joining surface and a detection surface provided opposite the joining surface, the joining surface having a depression and a light-shielding film provided over an area excluding the depression, the depression forming the flow path, the detection surface transmitting the light emitted from the flow path; and a wiring-side substrate having a joining surface and a conductive pattern provided with a varying thickness on the joining surface, the joining surface of the wiring-side substrate joining the joining surface of the detection-side substrate. In the area over which the light-shielding film is provided, adhesive is provided with a thickness corresponding to the varying thickness of the conductive pattern and the detection-side substrate and the wiring-side substrate are closely joined to each other with the adhesive.

Abstract: An exposure apparatus exposes a substrate through a liquid. The apparatus includes a stage that holds the substrate and moves, and a support plate disposed on the stage and around the periphery of the substrate and supporting the liquid together with the substrate. The support plate includes a liquid-repellent structure portion on the surface of which is formed a texture repellent to the liquid, and a flat portion on the surface of which is formed a film repellent to the liquid.

Abstract: An exposure mask of the present invention is an exposure mask for patterning a three-dimensional shape on a resist. The exposure mask comprises a first region where a plurality of openings having a first size smaller than a resolution limit of an exposure apparatus are arranged, a second region where a plurality of openings having a second size smaller than the first size are arranged, and a third region where the plurality of openings having the first size and the plurality of openings having the second size are mixed and arranged between the first region and the second region.

Abstract: An exposure apparatus includes (a) a projection optical system to project a reticle pattern onto a plate by using a light from a light source, and (b) a photo detector unit to detect the light via the projection optical system. The photo detector unit includes (i) a substrate, which is patterned with a wiring pattern and transmits the light, (ii) a detector to detect the light, and (iii) a bump to space the substrate from the detector, and to electrically connect the detector and the wiring pattern of the substrate.

Abstract: A member of an immersion exposure apparatus for exposing an image of a pattern of an original on a substrate via a liquid, and configured to be in contact with the liquid, includes a base portion, and a plurality of protruded portions provided on the base portion, wherein a contact angle ? of a material of a surface of the protruded portions before the protruded portions are exposed with light from a light source is larger than 90 degrees with respect to the liquid, and wherein, a value obtained by dividing a sum of a surface area of a face of the base portion on which the plurality of protruded portions are provided and the surface area of the plurality of protruded portions, by an area of the face of the base portion on which the plurality of protruded portions are provided, is r, r>1/|cos ?| is satisfied.