Patents by Inventor Makoto Ohwaki

Makoto Ohwaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LACTOBACILLUS HAVING ABILITY TO INDUCE IL-12 PRODUCTION, AND METHOD FOR CULTURING SAME
    Publication number: 20150344841
    Abstract: A method of producing a large volume of Lactobacillus bacteria and increasing the activity of the obtained Lactobacillus is provided. The Lactobacillus is prepared by culturing in a culture medium and adding an alkaline chemical while controlling the pH, and sterilizing the Lactobacillus by applying stress in the later stage of the cultivation so as to produce Lactobacillus having the ability to induce IL-12 production. Applying stress is selected from the group consisting of: (a) cultivating without adding an alkaline chemical; (b) cultivating at a temperature range in which propagation is suppressed; (c) cultivating by adding 1% by weight or more of salt; and/or (d) cultivating at pH of 5 or below.
    Type: Application
    Filed: July 22, 2013
    Publication date: December 3, 2015
    Applicant: BIOGENICS KOREA cO., lTD.
    Inventors: Tatsuhiko KAN, Makoto OHWAKI
  • Skin preparations for external use
    Patent number: 6461627
    Abstract: Skin preparations for external use and cosmetics which contain a fermented soybean extract prepared by extracting with an organic solvent a fermentation product obtained by treating a soybean extract with one or more microorganisms selected from bifidobacteria. These preparations are excellent in the effects of relieving wrinkles and ameliorating rough skin.
    Type: Grant
    Filed: April 3, 2001
    Date of Patent: October 8, 2002
    Assignee: Kabushiki Kaisha Yakult Honsha
    Inventors: Minoru Ichioka, Toshiro Sone, Tomoko Hanamizu, Makoto Ohwaki, Katsuyoshi Chiba, Koji Miyazaki, Yoshio Hiraki, Satoshi Yoshikawa
  • Bifidobacterium strains having high IgA induction potential
    Patent number: 5192685
    Abstract: The present invention is to provide an easy, rapid method for screening a great amount of substances having IgA induction potential. The IgA induction potential herein mentioned means the potential to activate and enhance the activity of IgA production cells to produce secretory-type IgA in response to antigen. The present invention is to provide bacterial strains of genus Bifidobacterium obtained by the method for screening substances having IgA induction potential. More specifically, the present invention is to provide Bifidobacterium longum YIT 4062, Bifidobacterium breve YIT 4063 and Bifidobacterium breve YIT 4064. The three strains obtained by the present invention have high IgA induction potential.
    Type: Grant
    Filed: April 20, 1990
    Date of Patent: March 9, 1993
    Assignee: Kabushiki Kaisha Yakult Honsha
    Inventors: Hisako Yasui, Kazuhito Hayakawa, Makoto Ohwaki, Tatsuhiko Kan