Patents by Inventor Makoto SAHARA

Makoto SAHARA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240101138
    Abstract: A display system includes: a first display device displaying an image in a first region to cause the image to be visually recognized in a position at a first distance from a visual line of a driver of an auto-vehicle; a second display device displaying an image in a second region to cause the image to be visually recognized at a second distance greater than the first distance from the visual line; and a display controller displaying a warning image in the second region if a first condition is satisfied, moving the warning image to display a warning image in the first region if a second condition in which a warning level is higher than that of the first condition is satisfied after the first condition is satisfied, then updating the warning image to an updated warning image, and then moving the updated warning image to the second region.
    Type: Application
    Filed: August 30, 2023
    Publication date: March 28, 2024
    Inventors: Makoto HADA, Yusuke SAHARA, Yuki MASUYA, Midori WATANABE, Hanako HONMA
  • Publication number: 20230383345
    Abstract: The present invention provides genetic markers for identifying engraftable human cardiac ventricular progenitor cells. The engraftment markers of the invention include angiogenic markers and extracellular matrix markers. Human ventricular progenitor cells expressing these markers are capable of forming ventricular tissue in vivo that is vascularized and supported by an extracellular matrix. Methods of engrafting human cardiac ventricular progenitor cells by transplanting into a subject progenitor cells that express the engraftment markers are also provided.
    Type: Application
    Filed: August 14, 2023
    Publication date: November 30, 2023
    Inventors: Chuen Yan LEUNG, Jonathan CLARKE, Jiejia XU, Federica SANTORO, Makoto SAHARA, Kenneth CHIEN
  • Patent number: 11725244
    Abstract: The present invention provides genetic markers for identifying engraftable human cardiac ventricular progenitor cells. The engraftment markers of the invention include angiogenic markers and extracellular matrix markers. Human ventricular progenitor cells expressing these markers are capable of forming ventricular tissue in vivo that is vascularized and supported by an extracellular matrix. Methods of engrafting human cardiac ventricular progenitor cells by transplanting into a subject progenitor cells that express the engraftment markers are also provided.
    Type: Grant
    Filed: March 3, 2020
    Date of Patent: August 15, 2023
    Assignee: Procella Therapeutics AB
    Inventors: Chuen Yan Leung, Jonathan Clarke, Jiejia Xu, Federica Santoro, Makoto Sahara, Kenneth R. Chien
  • Publication number: 20200270685
    Abstract: The present invention provides genetic markers for identifying engraftable human cardiac ventricular progenitor cells. The engraftment markers of the invention include angiogenic markers and extracellular matrix markers. Human ventricular progenitor cells expressing these markers are capable of forming ventricular tissue in vivo that is vascularized and supported by an extracellular matrix. Methods of engrafting human cardiac ventricular progenitor cells by transplanting into a subject progenitor cells that express the engraftment markers are also provided.
    Type: Application
    Filed: March 3, 2020
    Publication date: August 27, 2020
    Inventors: Chuen Yan LEUNG, Jonathan CLARKE, Jiejia XU, Federica SANTORO, Makoto SAHARA, Kenneth R. CHIEN
  • Patent number: 10612094
    Abstract: The present invention provides genetic markers for identifying engraftable human cardiac ventricular progenitor cells. The engraftment markers of the invention include angiogenic markers and extracellular matrix markers. Human ventricular progenitor cells expressing these markers are capable of forming ventricular tissue in vivo that is vascularized and supported by an extracellular matrix. Methods of engrafting human cardiac ventricular progenitor cells by transplanting into a subject progenitor cells that express the engraftment markers are also provided.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: April 7, 2020
    Assignee: Procella Therapeutics AB
    Inventors: Chuen Yan Leung, Jonathan Clarke, Jiejia Xu, Federica Santoro, Makoto Sahara, Kenneth R. Chien
  • Publication number: 20170240964
    Abstract: The present invention provides genetic markers for identifying engraftable human cardiac ventricular progenitor cells. The engraftment markers of the invention include angiogenic markers and extracellular matrix markers. Human ventricular progenitor cells expressing these markers are capable of forming ventricular tissue in vivo that is vascularized and supported by an extracellular matrix. Methods of engrafting human cardiac ventricular progenitor cells by transplanting into a subject progenitor cells that express the engraftment markers are also provided.
    Type: Application
    Filed: February 15, 2017
    Publication date: August 24, 2017
    Inventors: Chuen Yan LEUNG, Jonathan CLARKE, Jiejia XU, Federica SANTORO, Makoto SAHARA, Kenneth R. CHIEN