Abstract: To provide an axle bearing having a low torque property and superior bearing lifetime. A hub bearing 6 is configured to rotatably support a wheel of a vehicle, and has a grease composition 10 sealed in an inner space thereof. The grease composition 10 contains a base oil and a thickener. The shear stress of the grease composition at the shear rate of 1,000-10,000 s?1 at 25° C. is 3,000 Pa or less. The viscosity of the grease composition is 1 Pas or less. The yield stress of the grease composition at 25° C. measured by a dynamic viscoelasticity analysis method using a rheometer is 1,300-3,000 Pa.

Abstract: To provide a hub bearing that is capable of reducing a delay in a response of the hub bearing and improving a steering stability of a vehicle. A hub bearing 1 includes an outer ring 2 serving as a stationary side raceway ring, a hub wheel 3 and an inner ring 5 serving as a rotatable side raceway ring, balls 4 serving as a plurality of rolling elements disposed between a raceway surface of the stationary side raceway ring and a raceway surface of the rotatable side raceway ring, and grease that lubricates a rolling contact part between each of the raceway surfaces and the rolling elements. The surface roughness of at least one raceway surface selected from the raceway surface of the stationary side raceway ring and the raceway surface of the rotatable side raceway ring in the rolling contact part is 0.03 ?mRa or less. Further, the grease has a traction coefficient in the rolling contact part of 0.04 or less at 40° C. when a vehicle speed is 20 km/h or more.

Abstract: The present invention aims to provide a method for preparing urothelial cells that can be applied to the treatments of urologic diseases, particularly, diseases caused by urothelial cell damage, diseases caused by loss of urothelial cells and dysfunction, and the like, urothelial cells prepared by said method, and a medium for inducing (generating) urothelial cells. Urothelial cells prepared by a method for inducing a urothelial cell, including a step of introducing at least one member selected from the group consisting of FOXA1 (Forkhead box A1) gene or an expression product thereof, TP63 (tumor protein P63) gene or an expression product thereof, MYCL (L-Myc) gene or an expression product thereof, and KLF4 (Kruppel-like factor 4) gene or an expression product thereof to a mammalian somatic cell as an exogeneous factor can be applied to the treatment of urologic diseases.

Abstract: A pharmaceutical composition containing a cell population with enriched M2 macrophage and a pharmaceutically acceptable carrier is provided. The composition is not trapped in the lungs when administered systemically, and accumulates at a disorder/inflammation site. Therefore, the pharmaceutical composition of the present invention is useful as an anti-inflammatory pharmaceutical composition.

Abstract: A sealing member of a bearing device for vehicle wheel including: a sealing plate having a sealing plate fitting section (7a) fitted to an inner circumferential surface of an outer ring, an annular support section (7c) extending radially inwardly from the sealing plate fitting section, and sealing lips provided on one side surface of the support section; and a slinger (8) having a slinger fitting section (8a) fitted to the outer circumferential surface of an inner ring (4) and an annular upright plate section (8b) extending radially outwardly from the slinger fitting section and facing the support section. The plurality of sealing lips are in contact with one side surface of the upright plate section or with the slinger fitting section, the support section is bent to form an annular groove section, and the outer peripheral portion of the upright plate section is bent to form a cylindrical wall section.

Abstract: A bearing device for vehicle wheel includes a sealing ring (71) that includes: a core bar (72) and sealing rubber (73). The sealing rubber (73) includes: a first sealing lip (73b) that is formed to the radial-direction outside of the fitting part (72a) and has a tip end part that is in sliding contact with a sealing plane part (3h); and a second sealing lip (73c) that is formed to the radial-direction inside of the fitting part (72a) and has a tip end part that is in sliding contact with the sealing plane part (3h). A flat surface (73e) that can be contacted by a press-fitting tool (P) and by the tip end part of the fitting part (72a) of another bearing device for vehicle wheel is formed between the first sealing lip (73b) and the second sealing lip (73c).

Abstract: This bearing device (1) for vehicle wheels comprises: an inner undercut part (8) provided in a portion at which an inner rolling surface (3d) formed on the inner side of an inner member (3) and an inner flange surface (3m) of the inner rolling surface (3d) intersect; an outer undercut part (9) provided in a portion at which an inner rolling surface (3c) formed on the outer side of the inner member (3) and an outer flange surface (3n) of the inner rolling surface (3c) intersect; and a vehicle wheel installation flange (3e) provided at a portion adjacent to the inner rolling surface (3c) formed on the outer side of the inner member (3), wherein, when the radius of curvature of the inner undercut part (8) is Ri, and the radius of curvature of the outer undercut part (9) is Ro, the relationship of Ri<Ro is satisfied.

Abstract: A sealing member of a bearing device for vehicle wheel including: a sealing plate having a sealing plate fitting section (7a) fitted to an inner circumferential surface of an outer ring, an annular support section (7c) extending radially inwardly from the sealing plate fitting section, and sealing lips provided on one side surface of the support section; and a slinger (8) having a slinger fitting section (8a) fitted to the outer circumferential surface of an inner ring (4) and an annular upright plate section (8b) extending radially outwardly from the slinger fitting section and facing the support section. The plurality of sealing lips are in contact with one side surface of the upright plate section or with the slinger fitting section, the support section is bent to form an annular groove section, and the outer peripheral portion of the upright plate section is bent to form a cylindrical wall section.

Abstract: A bearing device for vehicle wheel includes a sealing ring (71) that includes: a core bar (72) and sealing rubber (73). The sealing rubber (73) includes: a first sealing lip (73b) that is formed to the radial-direction outside of the fitting part (72a) and has a tip end part that is in sliding contact with a sealing plane part (3h); and a second sealing lip (73c) that is formed to the radial-direction inside of the fitting part (72a) and has a tip end part that is in sliding contact with the sealing plane part (3h). A flat surface (73e) that can be contacted by a press-fitting tool (P) and by the tip end part of the fitting part (72a) of another bearing device for vehicle wheel is formed between the first sealing lip (73b) and the second sealing lip (73c).

Abstract: This bearing device (1) for vehicle wheels comprises: an inner undercut part (8) provided in a portion at which an inner rolling surface (3d) formed on the inner side of an inner member (3) and an inner flange surface (3m) of the inner rolling surface (3d) intersect; an outer undercut part (9) provided in a portion at which an inner rolling surface (3c) formed on the outer side of the inner member (3) and an outer flange surface (3n) of the inner rolling surface (3c) intersect; and a vehicle wheel installation flange (3e) provided at a portion adjacent to the inner rolling surface (3c) formed on the outer side of the inner member (3), wherein, when the radius of curvature of the inner undercut part (8) is Ri, and the radius of curvature of the outer undercut part (9) is Ro, the relationship of Ri<Ro is satisfied.

Abstract: The present invention provides a subcutaneous injection product for cattle for inducing superovulation characterized by comprising aluminum hydroxide gel and an efficient amount of a gonadotropin, wherein the concentration of the aluminum hydroxide is, in terms of the amount of aluminum, higher than or equal to 0.2 mg/mL and lower than 1.0 mg/mL, which is a subcutaneous injection product that is useful for producing good calves and that can induce superovulation in a cow by a single administration. The present invention also provides a method for producing good calves undergoing steps of subcutaneously injecting the aforementioned injection product into a cow to thereby induce superovulation, inducing estrus in the cow, conducting artificial insemination, and then collecting fertilized eggs.

Abstract: A wheel bearing apparatus has a double row rolling bearing detachably united with a constant velocity universal joint. The double row rolling bearing has an outer member, an inner member, and double row rolling elements rollably disposed between the double row raceway surfaces of the outer member and inner member. The constant velocity universal joint has an outer joint member, a shoulder portion, and a shaft portion. A female thread is formed on the shaft portion. End faces of the shoulder portion and the caulked portion are formed with face splines, respectively. The face spline of the caulked portion has a portion where a tooth height of a tooth space of a portion radially outside the pitch circle diameter is set lower than that of other portions of the tooth space.

Abstract: A wheel bearing has a seal device formed as a pack seal with an annular sealing plate and slinger. The sealing plate has a metal core and an integrally adhered sealing member. The sealing member has a base portion, side lip and radial lip. The base portion covers an inner circumferential surface of the metal core. The radial lip slidingly contacts the cylindrical portion of the slinger. A garter spring is mounted on the radial lip. A tightening force of the garter spring is set to 50% or more of a total tightening force of the radial lip. The tightening force of the radial lip without the garter spring is set to 3N or more.

Abstract: A wheel bearing apparatus has an outer member, an inner member and double row rolling elements contained between outer raceway surfaces and inner raceway surfaces, respectively, of the outer member and the inner member. A vibration damping mechanism is mounted on a portion of the outer member or the inner member except at portions engaging with mating components.

Abstract: A wheel bearing apparatus has an outer member, an inner member and double row rolling elements contained between outer raceway surfaces and inner raceway surfaces, respectively, of the outer member and the inner member. A vibration damping mechanism is mounted on a portion of the outer member or the inner member except at portions engaging with mating components.

Abstract: The present invention provides a subcutaneous injection product for cattle for inducing superovulation characterized by comprising aluminum hydroxide gel and an efficient amount of a gonadotropin, wherein the concentration of the aluminum hydroxide is, in terms of the amount of aluminum, higher than or equal to 0.2 mg/mL and lower than 1.0 mg/mL, which is a subcutaneous injection product that is useful for producing good calves and that can induce superovulation in a cow by a single administration. The present invention also provides a method for producing good calves undergoing steps of subcutaneously injecting the aforementioned injection product into a cow to thereby induce superovulation, inducing estrus in the cow, conducting artificial insemination, and then collecting fertilized eggs.

Abstract: A sheet processing apparatus includes: a sheet conveying unit that conveys a sheet; a sheet stacking member on a placing surface of which the sheet conveyed by the sheet conveying unit is stacked; an edge aligning unit that aligns edges of sheets in a sheet conveying direction on the sheet stacking member; a first binding unit that binds the sheets aligned by the edge aligning unit using a binding member; and a second binding unit that binds the sheets aligned by the edge aligning unit without using a binding member. The sheet processing apparatus selects either of the first binding unit and the second binding unit and performs binding processing on the sheets. The first binding unit and the second binding unit are integrally constructed.

Abstract: A wheel bearing apparatus has a double row rolling bearing detachably united with a constant velocity universal joint. The double row rolling bearing has an outer member, an inner member, and double row rolling elements rollably disposed between the double row raceway surfaces of the outer member and inner member. The constant velocity universal joint has an outer joint member, a shoulder portion, and a shaft portion. A female thread is formed on the shaft portion. End faces of the shoulder portion and the caulked portion are formed with face splines, respectively. The face spline of the caulked portion has a portion where a tooth height of a tooth space of a portion radially outside the pitch circle diameter is set lower than that of other portions of the tooth space.

Abstract: A sheet processing apparatus includes: a sheet conveying unit that conveys a sheet; a sheet stacking member on a placing surface of which the sheet conveyed by the sheet conveying unit is stacked; an edge aligning unit that aligns edges of sheets in a sheet conveying direction on the sheet stacking member; a first binding unit that binds the sheets aligned by the edge aligning unit using a binding member; and a second binding unit that binds the sheets aligned by the edge aligning unit without using a binding member. The sheet processing apparatus selects either of the first binding unit and the second binding unit and performs binding processing on the sheets. The first binding unit and the second binding unit are integrally constructed.

Abstract: A wheel bearing has a seal device formed as a pack seal with an annular sealing plate and slinger. The sealing plate has a metal core and an integrally adhered sealing member. The sealing member has a base portion, side lip and radial lip. The base portion covers an inner circumferential surface of the metal core. The radial lip slidingly contacts the cylindrical portion of the slinger. A garter spring is mounted on the radial lip. A tightening force of the garter spring is set to 50% or more of a total tightening force of the radial lip. The tightening force of the radial lip without the garter spring is set to 3 N or more.