Abstract: The present invention provides a method of manufacturing a tank having a reinforcement fiber layer, the method comprising: a winding step of winding a fiber impregnated with resin by a predetermined number of windings; and a curing step of thermally curing the impregnating resin in the wound fiber to thereby form the reinforcement fiber layer. In the winding step, an end portion, being a winding end, of the fiber is tucked into an inner fiber layer which has already been wound to thereby insert at least a portion of a fixing region that is a part of the end portion into between fibers forming the outermost layer so that the end portion is fixed to the inner fiber layer.

Abstract: The present invention provides a method of manufacturing a tank having a reinforcement fiber layer, the method comprising: a winding step of winding a fiber impregnated with resin by a predetermined number of windings; and a curing step of thermally curing the impregnating resin in the wound fiber to thereby form the reinforcement fiber layer. In the winding step, an end portion, being a winding end, of the fiber is tucked into an inner fiber layer which has already been wound to thereby insert at least a portion of a fixing region that is a part of the end portion into between fibers forming the outermost layer so that the end portion is fixed to the inner fiber layer.

Abstract: A novel dipeptide compound inhibiting the enzymatic activity of HIV protease and an anti-AIDS medicine comprising this dipeptide compound as an effective component represented by formula (I) wherein R1, R2, and R3 independently represent C1-4 alkyl, alkoxyl, hydrogen etc . . . (provided that not all of the R1, R2, and R3 are hydrogen), R2 and R3 may form a ring together, R4 represents C1-4 alkyl or hydrogen; X is a methylene group or a sulfur atom; Y represents e.g., a five or six member monocycle or aryloxyalkyl having up to 12 carbon atoms (provided that the aromatic ring may be substituted by alkyl etc . . . ); and Z represents a C1-6 aliphatic hydrocarbon or an aromatic hydrocarbon having up to 12 carbon atoms (provided that this aromatic ring may be substituted by alkyl etc . . . , or at least one carbon atom in the aromatic hydrocarbon may be replaced by a hereto atom).

Abstract: A AIDS therapeutic composition comprising medicaments which possess an HIV protease inhibition activity which is designed so that each medicament can achieve a higher treatment effect. The composition comprises KNI-272 and one compound selected from the group consisting of Saquinavir, Ritonavir, Indinavir, and Nelfinavir, exhibiting as essential active components a human immunodeficiency virus protease inhibition action, in such an amount and proportion to exhibit a synergistic treatment effect.

Abstract: A novel dipeptide compound inhibiting the enzymatic activity of HIV protease, an anti-AIDS medicine comprising this dipeptide compound as an effective component.

Abstract: &bgr;-Amino-&agr;-hydroxycarboxylic acid derivatives represented by the following formula and salts thereof which are useful as human immunodeficiency virus (HIV) protease inhibitors: The compounds are effective for treating a patient suffering from AIDS and AIDS related diseases.

Abstract: &bgr;-Amino-&agr;-hydroxycarboxylic acid derivatives represented by the following formula and salts thereof which are useful as human immunodeficiency virus (HIV) protease inhibitors: The compounds are effective for treating a patient suffering from AIDS and AIDS related diseases.