Patents by Inventor Makoto Yanai

Makoto Yanai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5576335
    Abstract: Urea derivatives of formula (1) ##STR1## wherein the valuable groups are as defined in the specification, which possess both an ACAT inhibitory activity and an antioxidative activity. Those derivatives are useful in the prophylaxis and treatment of hypercholesterolemia and atherosclerosis.
    Type: Grant
    Filed: September 29, 1994
    Date of Patent: November 19, 1996
    Assignee: Nisshin Flour Milling Co., Ltd.
    Inventors: Noriyoshi Sueda, Kazuhiko Yamada, Makoto Yanai, Katsutoshi Miura, Masato Horigome, Norio Oshida, Shigeru Hiramoto, Koichi Katasuyama, Fumihisa Nakata, Nobuhiro Kinoshita, Yoko Tsukada
  • Patent number: 5256656
    Abstract: Azabicyclo derivatives of formula (I) and pharmaceutically acceptable salts thereof: ##STR1## wherein A is a group of formula (a), (b) or (c): ##STR2## wherein R.sub.1 is hydrogen, C.sub.1 -C.sub.10 alkyl, aralkyl or di(C.sub.1 -C.sub.4) alkylamino(C.sub.1 -C.sub.6)alkyl;R.sub.2, R.sub.3 and R.sub.4 may be the same or different and each is hydrogen, amino, halogen, C.sub.1 -C.sub.4 alkoxy or phthalimide;X is O or NH;R is C.sub.1 -C.sub.4 alkyl; andY is NR, O or S;having 5-HT.sub.3 receptor antagonist activity.
    Type: Grant
    Filed: May 12, 1992
    Date of Patent: October 26, 1993
    Assignee: Nisshin Flour Milling Co., Ltd.
    Inventors: Haruhiko Kikuchi, Hiroaki Satoh, Nobuhiro Yahata, Kiochiro Hagihara, Toru Hayakawa, Setsuko Mino, Makoto Yanai
  • Patent number: 5187166
    Abstract: Azabicyclo derivatives of formula (I) and pharmaceutically acceptable salts thereof: ##STR1## wherein A is a group of formula (a), (b) or (c): ##STR2## wherein R.sub.1 is hydrogen, C.sub.1 -C.sub.10 alkyl, aralkyl or di(C.sub.1 -C.sub.4) alkylamino(C.sub.1 -C.sub.6)alkyl;R.sub.2, R.sub.3 and R.sub.4 may be the same or different and each is hydrogen, amino, halogen, C.sub.1 -C.sub.4 alkoxy or phthalimide; X is O or NH;R is C.sub.1 -C.sub.4 alkyl; andY is NR, O or S;having 5-HT.sub.3 receptor antagonist activity.
    Type: Grant
    Filed: July 16, 1991
    Date of Patent: February 16, 1993
    Assignee: Nisshin Flour Milling Co., Ltd.
    Inventors: Haruhiko Kikuchi, Hiroaki Satoh, Nobuhiro Yahata, Koichiro Hagihara, Toru Hayakawa, Setsuko Mino, Makoto Yanai
  • Patent number: 5124324
    Abstract: Disclosed are compounds of formula I ##STR1## wherein R.sub.1 is a hydrogen atom, a C.sub.1 -C.sub.6 alkyl group, benzyl or an indolyl carbonyl group, R.sub.2 is a saturated or unsaturated 5- or 8-membered heterocyclic group containing as a hetero atom one or more nitrogen atoms, the heterocyclic group is optionally substituted at an N or C atom by a C.sub.1 -C.sub.6 alkyl or aralkyl group, n is an integer of 1 to 5 and one or more hydrogen atoms, in an alkylene chain --(CH.sub.2).sub.n -- are optionally substituted by a C.sub.1 -C.sub.6 alkyl, phenyl and/or hydroxyl group, physiologically acceptable salts and quaternary ammonium salts thereof. The compounds are selective antagonists of 5-HT.sub.3 receptors and are useful in the treatment of psychotic disorders, neurotic diseases, gastric stasis symptoms, gastrointestinal disorders, nausea and vomiting.
    Type: Grant
    Filed: November 16, 1990
    Date of Patent: June 23, 1992
    Assignee: Nisshin Flour Milling Co., Ltd.
    Inventors: Haruhiko Kikuchi, Hiroaki Satoh, Makoto Yanai, Toshio Suguro, Koichiro Hagihara
  • Patent number: 4982210
    Abstract: A flash device in which a mechanism for shifting a light emitting section up and down and a mechanism for changing over the light distribution angle can be automatically controlled by means of a single motor and which occupies a comparatively small spacing when mounted on a camera. The flash device includes a bidirectional drive motor mounted in a body member, and a shiftable member having the light emitting section thereon. The shiftable member is shifted by rotation of the motor in either direction between a retracted inoperative position and a projected operative position. The light distribution angle of the light emitting section is changed over by continued energization of the motor after the shiftable member is moved from the inoperative to the operative position. A friction mechanism is interposed in a motion transmitting mechanism from the motor to the shiftable member.
    Type: Grant
    Filed: May 10, 1989
    Date of Patent: January 1, 1991
    Assignee: Minolta Camera Kabushiki Kaisha
    Inventors: Takahisa Shimada, Togo Teramoto, Toshihiko Taniguchi, Nobuharu Murashima, Makoto Yanai
  • Patent number: 4886803
    Abstract: Compounds are described of formula (I) ##STR1## wherein R.sup.1 is a hydrogen atom, an alkyl group, an alkoxy group, a dialkylamino group or a halogen atom; n is 1 to 4; R.sup.2 is a hydrogen atom, an alkyl group, an unsubstituted or substituted aminoalkyl group, an acyl group, an unsubstituted or substituted aralkyl group, a carboxyalkyl group, an alkoxycarbonyalkyl group or ##STR2## wherein X is an unsubstituted or substituted-phenyl, -benzyl, -benzoyl or -furoyl group; A is -NR.sup.3 - where R.sup.3 is hydrogen or alkyl, an alkylene or an alkylidene; and B is a heterocyclic group selected from triazolyl, pyridyl, pyridazinyl, pyrimidinyl, pyrazinyl, benzimidazolyl, benzothiazolyl, quinolyl and isoquinolyl, said heterocyclic group being optionally substituted by one or more alkyl, alkoxy, nitro or phenyl group, and the physiologically acceptable acid addition salts thereof. The compound of formula (I) are or cardiotonic activity and thus may be useful for the treatment of circulatory diseases.
    Type: Grant
    Filed: July 15, 1987
    Date of Patent: December 12, 1989
    Assignee: Nisshin Flour Milling Co., Ltd.
    Inventors: Noriyoshi Sueda, Yoshikuni Suzuki, Toshiji Sugai, Hiroaki Yamada, Makoto Yanai
  • Patent number: D321359
    Type: Grant
    Filed: September 22, 1988
    Date of Patent: November 5, 1991
    Assignee: Minolta Camera Kabushiki Kaisha
    Inventors: Tatsuro Izumi, Makoto Yanai
  • Patent number: D321525
    Type: Grant
    Filed: September 22, 1988
    Date of Patent: November 12, 1991
    Assignee: Minolta Camera Kabushiki Kaisha
    Inventors: Tatsuro Izumi, Makoto Yanai