Patents by Inventor Maksim Plikus

Maksim Plikus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200121760
    Abstract: This invention describes methods for treating wound healing pathologies, inhibiting or reversing fibrotic skin disorders, including but not limited to keloids, atrophic and hypertrophic scars, and reversing skin aging via generating new dermal adipocytes (DAs). Methods described herein comprise (a) grafting of human hair follicles or (b) direct delivery of conditioned media from in vitro cultured hair follicles, or (c) delivery of purified individual factors secreted by hair follicles, or (d) delivery of small molecule agonists that mimic hair derived signaling activities, or (e) delivery of small molecule antagonists that inhibit anti-adipogenic programs, or (f) delivery of small molecule agonists of pro-adipogenic programs to convert endogenous wound or scar skin fibroblasts into new DAs.
    Type: Application
    Filed: January 3, 2018
    Publication date: April 23, 2020
    Applicant: The Trustees of the University ofPennsylvania
    Inventors: George COTSARELIS, Christian F. Guerrero-Juarez, Maksim Plikus
  • Publication number: 20110293526
    Abstract: The invention provides compositions and methods to modulate hair growth in a tissue comprising administering to the tissue an effective amount of an agent that inhibits or augments Bone Morphogenic Protein (BMP) signaling in the tissue, thereby facilitating or inhibiting hair growth.
    Type: Application
    Filed: November 19, 2009
    Publication date: December 1, 2011
    Inventors: Maksim Plikus, Cheng Ming Chuong