Abstract: A method includes providing, for each respective audio channel of a plurality of audio channels provided by an operating system of a computing device, a set of successive audio processing stages to apply to the respective audio channel. The method also includes providing, by the operating system, an application programming interface (API) configured to set a plurality of parameters for adjusting the set of successive audio processing stages for each respective audio channel. The method additionally includes receiving, via the API and from an application running on the computing device, one or more values for one or more parameters of the plurality of parameters. The method further includes adjusting, by the operating system, the plurality of audio channels based on the received one or more values for the one or more parameters.

Abstract: High-surface area carbon nanotubes having targeted, or selective, oxidation levels and/or content on the interior and exterior of the tube walls are claimed. Such carbon nanotubes can have little to no inner tube surface oxidation, or differing amounts and/or types of oxidation between the tubes' inner and outer surfaces. Additionally, such high-surface area carbon nanotubes may have greater lengths and diameters, creating useful mechanical, electrical, and thermal properties.

Abstract: High-surface area carbon nanotubes having targeted, or selective, oxidation levels and/or content on the interior and exterior of the tube walls are claimed. Such carbon nanotubes can have little to no inner tube surface oxidation, or differing amounts and/or types of oxidation between the tubes' inner and outer surfaces. Additionally, such high-surface area carbon nanotubes may have greater lengths and diameters, creating useful mechanical, electrical, and thermal properties.

Abstract: High-surface area carbon nanotubes having targeted, or selective, oxidation levels and/or content on the interior and exterior of the tube walls are claimed. Such carbon nanotubes can have little to no inner tube surface oxidation, or differing amounts and/or types of oxidation between the tubes' inner and outer surfaces. Additionally, such high-surface area carbon nanotubes may have greater lengths and diameters, creating useful mechanical, electrical, and thermal properties.

Abstract: The present application pertains to dispersions comprising oxidized, discrete carbon nanotubes and high-surface area carbon nanotubes. The oxidized, discrete carbon nanotubes comprise an interior and exterior surface, each surface comprising an interior surface oxidized species content and an exterior surface oxidized species content. The interior surface oxidized species content differs from the exterior surface oxidized species content by at least 20%, and as high as 100%. The high-surface area nanotubes are generally single-wall nanotubes. The BET surface area of the high-surface area nanotubes is from about 550 m2/g to about 1500 m2/g according to ASTM D6556-16. The aspect ratio is at least about 500 up to about 6000. The dispersions comprise from about 0.1 to about 30% by weight nanotubes based on the total weight of the dispersion.

Abstract: High-surface area carbon nanotubes having targeted, or selective, species of oxygen containing species levels, types and/or content on either or both of the interior and exterior of the tube walls are claimed. Such carbon nanotubes can have little to none inner tube surface oxygen containing species, or differing amounts and/or types of oxygen containing species between the tubes' inner and outer surfaces or amongst the carbon nanotubes. Additionally, such high-surface area carbon nanotubes or their assemblages may have greater lengths and diameters, creating useful mechanical, electrical, and thermal properties.

Abstract: High-surface area carbon nanotubes having targeted, or selective, oxidation levels and/or content on the interior and exterior of the tube walls are claimed. Such carbon nanotubes can have little to no inner tube surface oxidation, or differing amounts and/or types of oxidation between the tubes' inner and outer surfaces. Additionally, such high-surface area carbon nanotubes may have greater lengths and diameters, creating useful mechanical, electrical, and thermal properties.

Abstract: A composition comprising discrete functionalized carbon nanotubes attached to microfibrillated fibers and a plurality of the discrete carbon nanotubes are opened ended is disclosed. The composition may further comprise electroactive, photoactive, magnetic or catalyst particles. These new compositions can be used in energy storage or energy collection devices such as batteries, capacitors, photovoltaics and sensors.

Abstract: The present invention pertains generally to the field of therapeutic compounds, and more specifically to 3-substituted-8-substituted-3H-imidazo[5,1-d][1,2,3,5]tetrazin-4-one compounds of the following formula, wherein -A and —B are as defined herein (collectively referred to herein as 38TM compounds): The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit cell proliferation, and in the treatment of proliferative disorders such as cancer, etc., and methods of preparing such compounds.

Abstract: The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain 3-substituted-4-oxo-3,4-dihydro-imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid amide (collectively referred to herein as 3TM compounds). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit cell proliferation, and in the treatment of proliferative disorders such as cancer, etc., and methods of preparing such compounds.

Abstract: The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain 3-substituted-4-oxo-3,4-dihydro-imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid amide (collectively referred to herein as 3TM compounds). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit cell proliferation, and in the treatment of proliferative disorders such as cancer, etc., and methods of preparing such compounds.

Abstract: In one embodiment, a method includes sending an indicator of an availability of a sample from a sample pool stored in a physical inventory. The sample being included in the sample pool based on an attribute of the sample satisfying a condition associated with the sample pool. An indicator that the sample has been selected from the sample pool for analysis at a first test site included in an array of test sites is received. A rule is retrieved from a rule database based on an experimental parameter value associated with the first test site. At least one of the experimental parameter value associated with the first test site or an experimental parameter value associated with a second test site is modified based on a condition within the rule being satisfied.

Abstract: The present invention pertains generally to the field of therapeutic compounds, and more specifically to 3-substituted-8-substituted-3H-imidazo[5,1-d][1,2,3,5]tetrazin-4-one compounds of the following formula, wherein -A and —B are as defined herein (collectively referred to herein as 38TM compounds): The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit cell proliferation, and in the treatment of proliferative disorders such as cancer, etc., and methods of preparing such compounds.

Abstract: One example of a seismic vibrator system includes a baseplate having a bottom surface and a coupling mechanism, the coupling mechanism being operable to a deployed position; a hold-down mass connected to the baseplate; a lifting mechanism in operational connection with the hold-down mass and the baseplate to apply a selected hold-down weight to the baseplate; and a driving mechanism functionally connected to the baseplate to transmit seismic energy through the baseplate into a ground surface to which the baseplate is coupled, wherein the coupling mechanism is urged outward from the bottom surface and into physical contact with the ground surface when operated to the deployed position.

Abstract: The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain 3-substituted-4-oxo-3,4-dihydro-imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid amide (collectively referred to herein as 3TM compounds). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit cell proliferation, and in the treatment of proliferative disorders such as cancer, etc., and methods of preparing such compounds.

Abstract: In one embodiment, a method includes sending an indicator of an availability of a sample from a sample pool stored in a physical inventory. The sample being included in the sample pool based on an attribute of the sample satisfying a condition associated with the sample pool. An indicator that the sample has been selected from the sample pool for analysis at a first test site included in an array of test sites is received. A rule is retrieved from a rule database based on an experimental parameter value associated with the first test site. At least one of the experimental parameter value associated with the first test site or an experimental parameter value associated with a second test site is modified based on a condition within the rule being satisfied.

Abstract: One example of a seismic vibrator system includes a baseplate having a bottom surface and a coupling mechanism, the coupling mechanism being operable to a deployed position; a hold-down mass connected to the baseplate; a lifting mechanism in operational connection with the hold-down mass and the baseplate to apply a selected hold-down weight to the baseplate; and a driving mechanism functionally connected to the baseplate to transmit seismic energy through the baseplate into a ground surface to which the baseplate is coupled, wherein the coupling mechanism is urged outward from the bottom surface and into physical contact with the ground surface when operated to the deployed position.

Abstract: Methods of determining status of an individual based on the use of biological specimen and analysis of reference population of cells are described.

Abstract: A compound of general structure I, wherein the compound is optionally in the form of an N-oxide or S-oxide or prodrug form and/or pharmaceutically acceptable salt thereof wherein: each of R1 to R9 is independently selected from hydrogen, hydroxyl, alkoxy, halo, mesyl, CX3 (X=halo), —O(CH2)nNYZ-, substituted or unsubstituted lower alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted aryl or heteroaryl, and substituted or unsubstituted aralkyl or heteroaralkyl; optionally R6 and R7 together form a dioxymethylene (—OCH2O—) unit and wherein n is 1 to 3 and Y and Z are independently selected from any of the following: C1-C6 straight chain, branched or cyclic substituted or unsubstituted alkyl group, Y and Z can be taken together to form a cyclic alkyl or hetereoalkyl group wherein in addition to N the hetereoalkyl group comprises a heteroatom selected from N, O or S.

Abstract: This invention pertains to certain 4-(1-(sulfonyl)-1H-indol-2-yl)-4-(hydroxy)-cyclohexa-2,5-dienone compounds, and analogs thereof, including compounds of the following formula, which are, inter alia, antiproliferative agents, anticancer agents, and/or thioredoxin/thioredoxin reductase inhibitors: formula (I) wherein: Ar is a 1-(sulfonyl)-1H-indol-2-yl group; the bond marked ? is independently: (a) a single bond; or: (b) a double bond; the bond marked ? is independently: (a) a single bond; or: (b) a double bond; the group —ORO is independently: (a) —OH; (b) an ether group (e.g., —OMe); or: (c) an acyloxy (i.e., reverse ester) group (e.g.