Patents by Inventor Malcolm Keith Brenner

Malcolm Keith Brenner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Herpesvirus vectors and their uses
    Publication number: 20030083289
    Abstract: A process of treating a human or non-human animal cell to introduce heterologous genetic material into said cell and express said material in said cell, comprises (a) providing a recombinant herpesviral vector which is an attenuated or replication-defective and non-transforming mutant herpesvirus, and which carries heterologous genetic material, and (b) transducing human or non-human animal cells selected from: hemopoietic cells, malignant cells related to blood cells, and malignant or non-malignant CD34 + cells; by contacting said cells with said virus vector to transduce said cells and express said genetic material. Among applications of the technique is modification of hemopoietic cells by transfer of genes, e.g. to generate tumor immunogens from malignant cells.
    Type: Application
    Filed: January 8, 2002
    Publication date: May 1, 2003
    Inventors: Michael Edward Griffith Boursnell, Malcolm Keith Brenner, Dagmar Dilloo, Stephen Charles Inglis
  • Herpes virus vectors and their uses
    Patent number: 6344445
    Abstract: A process of treating a human or non-human animal cell to introduce heterologous genetic material into said cell and express said material in said cell, comprises (a) providing a recombinant herpesviral vector which is an attenuated or replication-defective and non-transforming mutant herpesvirus, and which carries heterologous genetic material, and (b) transducing human or non-human animal cells selected from: hemopoietic cells, malignant cells related to blood cells, and malignant or non-malignant CD34+cells; by contacting said cells with said virus vector to transduce said cells and express said genetic material. Among applications of the technique is modification of hemopoietic cells by transfer of genes, e.g. to generate tumor immunogens from malignant cells.
    Type: Grant
    Filed: October 18, 1996
    Date of Patent: February 5, 2002
    Assignees: Cantab Pharmaceutical Research Limited, St. Jude Children's Research Hospital
    Inventors: Michael Edward Griffith Boursnell, Malcolm Keith Brenner, Dagmar Dilloo, Stephen Charles Inglis