Patents by Inventor Malcolm Kennard

Malcolm Kennard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for modulating blood-brain barrier transport
    Publication number: 20070167365
    Abstract: This invention provides conjugates of therapeutic or active agents with melanotransferrin or with other ligands of a melanotransferrin receptor, melanotransferrin receptor modulators, and related compositions and methods for modulating blood-brain barrier transport by, providing methods of screening and selecting such conjugates, ligands, and modulators in vitro and in vivo, and methods of use of such conjugates, modulators and ligands in diagnosis and the treatment of diseases, including particularly diseases of the central nervous system or lysosomal storage diseases.
    Type: Application
    Filed: October 13, 2006
    Publication date: July 19, 2007
    Inventors: Richard Beliveau, Michel Demeule, Joseph Yang, Malcolm Kennard, Reinhard Gabathuler
  • Use of p97 and iron binding proteins as diagnostic and therapeutic agents
    Publication number: 20030077693
    Abstract: The invention related to a GPI-anchored p97 and a soluble form of p97 and derivatives thereof and methods for preparing the same. Methods of using p97 in modulating iron transport, in the delivery of therapeutic agents, and in the treatment of conditions involving disturbances in iron metabolism are described. The treatment and diagnosis of Alzheimer's Disease in view of the finding that p97 and transferrin receptor are markers for microglial cells associated with senile plaques are also described.
    Type: Application
    Filed: April 29, 2002
    Publication date: April 24, 2003
    Applicant: University of British Columbia
    Inventors: Wilfred A. Jefferies, Patrick L. McGeer, Sylvia Rothenberger, Michael R. Food, Tatsuo Yamada, Malcolm Kennard
  • Use of p97 and iron binding proteins as diagnostic and therapeutic agents
    Patent number: 6455494
    Abstract: The invention related to a GPI-anchored p97 and a soluble form of p97 and derivatives thereof and methods for preparing the same. Methods of using p97 in modulating iron transport, in the delivery of therapeutic agents, and in the treatment of conditions involving disturbances in iron metabolism are described. The treatment and diagnosis of Alzheimer's Disease in view of the finding that p97 and transferrin receptor are markers for microglial cells associated with senile plaques are also described.
    Type: Grant
    Filed: April 1, 1999
    Date of Patent: September 24, 2002
    Assignee: University of British Columbia
    Inventors: Wilfred A. Jefferies, Patrick L. McGeer, Sylvia Rothenberger, Michael R. Food, Tatsuo Yamada, Malcolm Kennard
  • Use of p97 and iron binding proteins as diagnostic and therapeutic agents
    Patent number: 5981194
    Abstract: The invention related to a GPI-anchored p97 and a soluble form of p97 and derivatives thereof and methods for preparing the same. Methods of using p97 in modulating iron transport, in the delivery of therapeutic agents, and in the treatment of conditions involving disturbances in iron metabolism are described. The treatment and diagnosis of Alzheimer's Disease in view of the finding that p97 and transferrin receptor are markers for microglial cells associated with senile plaques are also described.
    Type: Grant
    Filed: August 31, 1995
    Date of Patent: November 9, 1999
    Assignee: University of British Columbia
    Inventors: Wilfred A. Jefferies, Patrick L. McGeer, Sylvia Rothenberger, Michael R. Food, Tatsuo Yamada, Malcolm Kennard