Abstract: Described herein is a method for detecting cancer DNA in a test sample of DNA from a patient. In some embodiments, the method may comprise: (a) sequencing multiple aliquots of the test sample to produce, for each aliquot, sequence reads corresponding to two or more target regions that each have one or more sequence variations present within the patient's cancer; (b) for each aliquot, for each target region: i. determining the number of sequence reads that have the sequence variation; ii. determining the total number of sequence reads; and iii. comparing i. and ii. to one or more error probability distribution models for the sequence variation, wherein the one or more models are obtained from DNA that does not contain the sequence variation; and (c) integrating the collective results of step (b) to determine if there is cancer DNA in the test sample.

Abstract: Electronics cabinet comprising an enclosure (1) with an interior space (2) where electronic parts, such as circuit cards and the like, can be mounted, and a cooling system (3) arranged as a substantially integral assembly with the enclosure in the immediate vicinity of its interior space for cooling the interior space. The cooling system (3) comprises means for internal air circulation within the interior space, for conveying an external air circulation separated from the internal air circulation into and out of the cooling system and for cooling the air in the internal circulation. The means for conveying the internal and/or external air circulation comprise a body (4) made from a foamed material with a flow channel (5, 6, 7) formed in it, through which at least part of the internal and/or external air circulation is passed.