Patents by Inventor Malcolm Rice Bell

Malcolm Rice Bell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-Saccharinylmethyl heterocyclic carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof
    Patent number: 5856349
    Abstract: 4-R.sup.4 -R.sup.5 -2-Saccharinylmethyl heterocyclic carboxylates, useful in the treatment of degenerative diseases, are prepared by reacting a 4-R.sup.4 -R.sup.5 -2-halomethylsaccharin with either a heterocyclic carboxylic acid in the presence of an acid-acceptor or the alkali metal salt of a heterocyclic carboxylic acid.
    Type: Grant
    Filed: June 6, 1997
    Date of Patent: January 5, 1999
    Assignee: Sanofi
    Inventors: Richard Paul Dunlap, Dennis John Hlasta, Ranjit Chimanlal Desai, Lee Hamilton Latimer, Chakrapani Subramanyam, John Joseph Court, Malcolm Rice Bell, Virendra Kumar
  • 3-arylcarbonyl-1-(C-attached-N-heteryl)-1H-indoles
    Patent number: 5817651
    Abstract: 2-R.sub.2 --R.sub.4 -substituted-3-R.sub.3 --CO-1-?(C-attached-N-heteryl)-(Alk) .sub.n !-1H-indoles useful as analgesic, anti-rheumatic, anti-inflammatory or anti-glaucoma agents.
    Type: Grant
    Filed: January 14, 1997
    Date of Patent: October 6, 1998
    Assignee: Sanofi
    Inventors: Thomas Edward D'Ambra, Edward Richard Bacon, Malcolm Rice Bell, Philip Michael Carabateas, Michael Allen Eissenstat, Virendra Kumar, John Peter Mallamo, Susan Jean Ward
  • 2-saccharinylmethyl heterocyclic carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof
    Patent number: 5652254
    Abstract: 4-R.sup.4 -R.sup.5 -2-Saccharinylmethyl heterocyclic carboxylates, useful in the treatment of degenerative diseases, are prepared by reacting a 4-R.sup.4 -R.sup.5 -2-halomethylsaccharin with either a heterocyclic carboxylic acid in the presence of an acid-acceptor or the alkali metal salt of a heterocyclic carboxylic acid.
    Type: Grant
    Filed: August 28, 1996
    Date of Patent: July 29, 1997
    Assignee: Sanofi, S.A.
    Inventors: Richard Paul Dunlap, Dennis John Hlasta, Ranjit Chimanlal Desai, Lee Hamilton Latimer, Chakrapani Subramanyam, John Joseph Court, Malcolm Rice Bell, Virendra Kumar
  • Anti-inflammatory 3-(substituted-amino)-2,1-benzisothiazoles
    Patent number: 4112105
    Abstract: 3-(Substituted-amino)-2,1,-benzisothiazoles useful as anti-inflammatory agents are prepared by reductive cyclization of appropriately substituted 2-nitrothiobenzamides or by reaction of 3-chloro-2,1-benzisothiazoles with suitably substituted amines.
    Type: Grant
    Filed: May 4, 1977
    Date of Patent: September 5, 1978
    Assignee: Sterling Drug Inc.
    Inventors: John Alan Carlson, Malcolm Rice Bell
  • 2,5-Dimethyl-1-pyrrole-lower-alkanecarboxamides
    Patent number: 4021566
    Abstract: 2,5-Dimethyl-1-pyrrole-lower-alkanecarboxamides, prepared by reaction of a 3-R.sub.3 -4-R.sub.4 -2,5-hexanedione with either an .omega.-amino-lower-alkanonitrile or an .omega.-amino-lower-alkanecarboxamide, and if appropriate, hydrolysis of the resulting 2,5-dimethyl-3-R.sub.3 -4-R.sub.4 -1-pyrrole-lower-alkano-nitrile, have anti-secretory and anti-ulcer activities.
    Type: Grant
    Filed: October 21, 1975
    Date of Patent: May 3, 1977
    Assignee: Sterling Drug Inc.
    Inventor: Malcolm Rice Bell
  • 2-Substituted-indole-1-lower-alkanecarboxamides
    Patent number: 4021448
    Abstract: 2-Substituted-indole-1-lower-alkanecarboxamides, prepared by amidation of the corresponding acid or ester; by hydrolysis or thiohydrolysis of the corresponding carbonitrile; by alkylation of a suitable indole with a halo-lower-alkanecarboxamide; or by hydrolysis of a 1-indolechlorosulfonylcarbamyl derivative, have anti-secretory and anti-ulcer activities.
    Type: Grant
    Filed: October 21, 1975
    Date of Patent: May 3, 1977
    Assignee: Sterling Drug Inc.
    Inventor: Malcolm Rice Bell