Patents by Inventor Malcolm S. Nobbs

Malcolm S. Nobbs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmacologically active CNS compounds
    Patent number: 5635507
    Abstract: A class of substituted phenylpyrimidine compounds are disclosed which are potent inhibitors of the excitatory amino acid, glutamate. Such compounds are useful in the treatment or prevention of a range of CNS disorders including cerebral ischaemic damage and epilepsy.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: June 3, 1997
    Assignee: Glaxo Wellcome Inc.
    Inventors: Alistair A. Miller, Malcolm S. Nobbs, Richard M. Hyde, Michael J. Leach
  • Treatment of injury of the spinal cord or brain using 4-amino-2-(4-methylpiperazin-1-yl)-5-(2,3,5-trichlorophenyl)pyrimidine
    Patent number: 5597827
    Abstract: A class of substituted phenylpyrimidine compounds are disclosed which are potent inhibitors of the excitatory amino acid, glutamate. Such compounds are useful in the treatment or prevention of a range of CNS disorders including cerebral ischaemic damage and epilepsy.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: January 28, 1997
    Inventors: Alistair A. Miller, Malcolm S. Nobbs, Richard M. Hyde, Michael J. Leach
  • Certain 2,4-diamino-5-(2,3-dihalophenyl)-6-substituted pyrimidines which are pharmacologically active CNS compounds
    Patent number: 5597828
    Abstract: A class of substituted phenylpyrimidine compounds are disclosed which are potent inhibitors of the excitatory amino acid, glutamate. Such compounds are useful in the treatment or prevention of a range of CNS disorders including cerebral ischaemic damage and epilepsy.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: January 28, 1997
    Assignee: Glaxo Wellcome Inc.
    Inventors: Alistair A. Miller, Malcolm S. Nobbs, Richard M. Hyde, Michael J. Leach
  • Treatment of damage from a stroke using 4-amino(4-methylpiperazin-1-yl)-5-(2,3,5-trichlorophenyl)pyrimidine
    Patent number: 5591746
    Abstract: A class of substituted phenylpyrimidine compounds are disclosed which are potent inhibitors of the excitatory amino acid, glutamate. Such compounds are useful in the treatment or prevention of a range of CNS disorders including cerebral ischaemic damage and epilepsy.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: January 7, 1997
    Inventors: Alistair A. Miller, Malcolm S. Nobbs, Richard M. Hyde, Michael J. Leach
  • Certain 2,4-diamino-5-(2,3,5-TRI-chlorophenyl)-6-substituted-pyrimidines which are pharmacologically active CNS compounds
    Patent number: 5587380
    Abstract: A class of substituted phenylpyrimidine compounds are disclosed which are potent inhibitors of the excitatory amino acid, glutamate. Such compounds are useful in the treatment or prevention of a range of CNS disorders including cerebral ischaemic damage and epilepsy.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 24, 1996
    Assignee: Glaxo Wellcome Inc.
    Inventors: Alistair A. Miller, Malcolm S. Nobbs, Richard M. Hyde, Michael J. Leach
  • Nitrile compounds
    Patent number: 5136080
    Abstract: A class of substituted phenylpyrimidine compounds are disclosed which are potent inhibitors of the excitatory amino acid, glutamate. Such compounds are useful in the treatment or prevention of a range of CNS disorders including cerebral ischaemic damage and epilepsy.
    Type: Grant
    Filed: June 5, 1990
    Date of Patent: August 4, 1992
    Assignee: Burroughs Wellcome Co.
    Inventors: Alistair A. Miller, Malcolm S. Nobbs, Richard M. Hyde, Michael John