Patents by Inventor MALCOLM WHITEWAY

MALCOLM WHITEWAY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THE G-PROTEIN B SUBUNIT INTERACTION DOMAIN OF STE20P/PAK FAMILY OF PROTEIN KINASES AND USES THEREOF IN BIOASSAYS
    Publication number: 20020106690
    Abstract: The present invention relates generally to signal transduction through G-protein-coupled receptors and more particularly to the interaction between the &bgr; subunit of the heterotrimeric G-protein and the Ste20p/PAK family of protein kinases. More particularly, the invention is directed to the identification of the G-protein &bgr; subunit interaction domain of Ste20p/PAK family of protein kinases, the Ste20p/PAK interaction domain of G-protein &bgr; subunit, to antibodies specific for these interacting domains, the nucleic acid molecules encoding same, to assays, expression vectors, indicator cells, strains, methods and agents which make use of this Ste20p/PAK—G&bgr; interaction.
    Type: Application
    Filed: January 7, 1999
    Publication date: August 8, 2002
    Inventors: EKKEHARD LEBERER, THOMAS LEEUW, MALCOLM WHITEWAY, DAVID Y. THOMAS