Abstract: Disclosed embodiments include a server computer system that can create a patient profile identifying a group of individuals including a user of a client device and only one patient corresponding to an individual other than the user of the client device. The patient profile can include an assessment and a treatment for the patient based on the assessment. The server computer system can receive, from the client device over a computer network, data values selected by the user of the client device, where the data values are indicative of observations of the patient's activity. The server computer system can further update the patient profile based on the received data values such that the data values influence the treatment, and send, to the client device over the computer network, a message including guidance for the user of the client device to implement the treatment.

Abstract: Disclosed embodiments include a server computer system that can create a patient profile identifying a group of individuals including a user of a client device and only one patient corresponding to an individual other than the user of the client device. The patient profile can include an assessment and a treatment for the patient based on the assessment. The server computer system can receive, from the client device over a computer network, data values selected by the user of the client device, where the data values are indicative of observations of the patient's activity. The server computer system can further update the patient profile based on the received data values such that the data values influence the treatment, and send, to the client device over the computer network, a message including guidance for the user of the client device to implement the treatment.

Abstract: Disclosed embodiments include a server computer system that can create a patient profile identifying a group of individuals including a user of a client device and only one patient corresponding to an individual other than the user of the client device. The patient profile can include an assessment and a treatment for the patient based on the assessment. The server computer system can receive, from the client device over a computer network, data values selected by the user of the client device, where the data values are indicative of observations of the patient's activity. The server computer system can further update the patient profile based on the received data values such that the data values influence the treatment, and send, to the client device over the computer network, a message including guidance for the user of the client device to implement the treatment.

Abstract: Risk engines and related methods may benefit patients and their physicians. For example, patients may benefit from being able to determine their personal genetic, environmental, and behavioral risks. Moreover, physicians may be able to provide statistically-driven individual recommendations based on a risk engine's determination of such risks. A method can include selecting one or more candidate genetic variants associated with a phenotype from the scientific literature. The method can also include scoring a genetic association between the one or more candidate genetic variants and the phenotype. The method can further include selecting one or more high-scoring genetic variants. Selecting a best genetic variant within each of at least one linkage disequilibrium (LD) block can also be included in the method. The method can additionally include calculating risk associated with the best genetic variant from the at least one LD block.