Patents by Inventor Malika Serra-Hassoun

Malika Serra-Hassoun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transgenic Immunodeficient Mouse Expressing Human SIRP-alpha
    Publication number: 20180160662
    Abstract: The present invention provides a transgenic mouse which comprises a deficiency for murine T lymphocytes, B lymphocytes and NK cells, a deficiency for murine MHC class I and MHC class II molecules, and a functional xenogenic SIRP? transgene. This mouse is useful for in vivo screening of various compounds, including immuno-therapeutic agents and vaccines. The said mouse is also useful for testing the in vivo metabolism of xenobiotic compounds.
    Type: Application
    Filed: January 25, 2018
    Publication date: June 14, 2018
    Applicant: Institut Pasteur
    Inventors: Sylvie GARCIA, Malika SERRA-HASSOUN
  • Transgenic immunodeficient mouse expressing human SIRP-alpha
    Patent number: 9894888
    Abstract: The present invention provides a transgenic mouse which comprises a deficiency for murine T lymphocytes, B lymphocytes and NK cells, a deficiency for murine MHC class I and MHC class II molecules, and a functional xenogenic SIRP? transgene. This mouse is useful for in vivo screening of various compounds, including immuno-therapeutic agents and vaccines. The said mouse is also useful for testing the in vivo metabolism of xenobiotic compounds.
    Type: Grant
    Filed: March 26, 2013
    Date of Patent: February 20, 2018
    Assignee: INSTITUT PASTEUR
    Inventors: Sylvie Garcia, Malika Serra-Hassoun
  • Transgenic Immunodeficient Mouse Expressing Human SIRP-alpha
    Publication number: 20150056636
    Abstract: The present invention provides a transgenic mouse which comprises a deficiency for murine T lymphocytes, B lymphocytes and NK cells, a deficiency for murine MHC class I and MHC class II molecules, and a functional xenogenic SIRP? transgene. This mouse is useful for in vivo screening of various compounds, including immuno-therapeutic agents and vaccines. The said mouse is also useful for testing the in vivo metabolism of xenobiotic compounds.
    Type: Application
    Filed: March 26, 2013
    Publication date: February 26, 2015
    Inventors: Sylvie Garcia, Malika Serra-Hassoun