Patents by Inventor Malin Lemurell

Malin Lemurell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-azetidinone derivatives as cholesterol absorption inhibitors for the treatment of hyperlipidaemic conditions
    Patent number: 7893048
    Abstract: Compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Grant
    Filed: June 21, 2006
    Date of Patent: February 22, 2011
    Assignee: AstraZeneca AB
    Inventors: Susanne Alenfalk, Mikael Dahlstrom, Fana Hunegnaw, Staffan Karlsson, Malin Lemurell, Ingemar Starke
  • Diphenylazetidinone derivatives possessing cholesterol absorption inhibitory activity
    Patent number: 7871998
    Abstract: Compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Grant
    Filed: December 21, 2004
    Date of Patent: January 18, 2011
    Assignee: AstraZeneca AB
    Inventors: Susanne Alenfalk, Mikael Dahlström, Fana Hunegnaw, Staffan Karlsson, Malin Lemurell, Ann-Margret Lindqvist, Tore Skjäret, Ingemar Starke
  • 2-azetidinone derivatives and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia
    Patent number: 7863265
    Abstract: Compounds of formula (I) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Grant
    Filed: June 19, 2006
    Date of Patent: January 4, 2011
    Assignee: AstraZeneca AB
    Inventors: Susanne Alenfalk, Mikael Dahlstrom, Fana Hunegnaw, Staffan Karlsson, Malin Lemurell, Ann-Margret Lindqvist, Tore Skjaret, Ingemar Starke
  • Diphenylazetidinone derivatives possessing cholesterol absorption inhibitor activity
    Patent number: 7842684
    Abstract: The present invention provides 2-azetidinone derivatives, or pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof, comprising formula (I): wherein the substituents are as herein defined. The compounds possess cholesterol absorption inhibitory activity and are accordingly of value in the treatment of disease states associated with hyperlipidaemic conditions.
    Type: Grant
    Filed: April 25, 2007
    Date of Patent: November 30, 2010
    Assignee: AstraZeneca AB
    Inventors: Malin Lemurell, Ingemar Starke
  • Novel 2-Azetidinone Derivatives And Their Use As Cholesterol Absorption Inhibitors For The Treatment Of Hyperlipidaemia
    Publication number: 20100216759
    Abstract: Compounds of formula (I) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Application
    Filed: June 19, 2006
    Publication date: August 26, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Susanne Alenfalk, Mikael Dahlstrom, Fana Hunegnaw, Staffan Karlsson, Malin Lemurell, Ann-Margret Lindqvist, Tore Skjaret, Ingemar Starke
  • Novel 2-Azetidinone Derivatives As Cholesterol Absorption Inhibitors For The Treatment Of Hyperlipidaemic Conditions
    Publication number: 20100168075
    Abstract: The application relates to novel 2-azetidinone derivatives of formula (I) and pharmaceutically acceptable salts, solvates and prodrugs thereof. The compounds are cholesterol absorption inhibitors and are useful in the treatment of hyperlipidaemic conditions, including atherosclerosis, Alzheimers' disease and cholesterol associated tumours. The application also relates to pharmaceutical formulations comprising such compounds and to processes for their preparation.
    Type: Application
    Filed: June 21, 2006
    Publication date: July 1, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Mikael Dahlstrom, Fana Hunegnaw, Malin Lemurell, Peter Nordberg, Tore Skjaret, Ingemar Starke
  • Novel 2-Azetidinone Derivatives As Cholesterol Absorption Inhibitors For The Treatment Of Hyperlipidaemic Conditions
    Publication number: 20100137273
    Abstract: Compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Application
    Filed: June 21, 2006
    Publication date: June 3, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Susanne Alenfalk, Mikael Dahlstrom, Fana Hunegnaw, Staffan Karlsson, Malin Lemurell, Ingemar Starke
  • Diphenylazetidinone Derivatives Possessing Cholesterol Absorption Inhibitory Activity
    Publication number: 20100099657
    Abstract: Compounds of formula (I) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Application
    Filed: November 16, 2006
    Publication date: April 22, 2010
    Applicant: AstraZeneca AB
    Inventors: Susanne Alenfalk, Mikael Dahlstrom, Fana Hunegnaw, Staffan Karlsson, Malin Lemurell, Ann-Margret Lindqvist, Tore Skjaret, Ingemar Starke
  • New 2-Azetidinone Derivatives Useful In The Treatment Of Hyperlipidaemic Conditions
    Publication number: 20100048529
    Abstract: The invention relates to compounds of formula (I) and pharmaceutically acceptable salts, solvates, and prodrugs thereof, and to their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia. The invention also relates to processes for their manufacture and pharmaceutical compositions containing them.
    Type: Application
    Filed: June 21, 2006
    Publication date: February 25, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Mikael Dahlstrom, Staffan Karlsson, Malin Lemurell, Peter Nordberg, Ingemar Starke
  • Diphenylazetidinone Derivatives Possessing Cholesterol Absorption Inhibitor Activity
    Publication number: 20090069285
    Abstract: 2-azetidinone derivatives and pharmaceutical compositions containing them. The compounds are useful in the treatment of hyperlipidemic conditions, atherosclerosis, Alzheimers' disease and cholesterol associated tumours.
    Type: Application
    Filed: April 25, 2007
    Publication date: March 12, 2009
    Applicant: ASTRAZENECA AB
    Inventors: Malin Lemurell, Ingemar Starke
  • Diphenylazetidinone Derivatives Possessing Cholesterol Absorption Inhibitory Activity
    Publication number: 20080064676
    Abstract: Compounds of formula (I) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Application
    Filed: December 21, 2004
    Publication date: March 13, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Susanne Alenfalk, Mikael Dahlstrom, Fana Hunegnaw, Staffan Karlsson, Malin Lemurell, Ann-Margret Lindqvist, Tore Skjaret, Ingemar Starke
  • Diphenylazetidinone derivatives possessing chloesterol absorption inhibitory activity
    Publication number: 20070142304
    Abstract: Compounds of formula (XV): [Chemical formula should be inserted here. Please see paper copy] (XV) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Application
    Filed: December 21, 2004
    Publication date: June 21, 2007
    Inventors: Susanne Alenfalk, Mikael Dahlstrom, Fana Hunegnaw, Staffan Karlsson, Malin Lemurell, Ann-Margret Lindqvist, Tore Skjaret, Ingemar Starke
  • Peptides derivatives comprising thiazepine group for the treatment of hyperlipidemic conditions
    Patent number: 7192947
    Abstract: The present invention relates to compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia.
    Type: Grant
    Filed: June 10, 2003
    Date of Patent: March 20, 2007
    Assignee: AstraZeneca AB
    Inventors: Ingemar Starke, Mikael Ulf Johan Dahlstrom, Suzanne Alenfalk, Tore Skjaret, Malin Lemurell
  • Benzothiazepine and benzothiazepine derivatives with ileal bile acid transport (IBAT) inhibotory activity for the treatment hyperlipidaemia
    Patent number: 7132416
    Abstract: The present invention relates to compounds of formula (I) wherein Rv, R1, R2, Rx, Ry, M, Rz, v, R3, R4, R5 and R6 are as defined within; pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: November 7, 2006
    Assignee: AstraZeneca AB
    Inventors: Ingemar Starke, Mikael Ulf Johan Dahlstrom, David Blomberg, Suzanne Alenfalk, Tore Skjaret, Malin Lemurell
  • Benzothiazepine and benzothiepine derivatives
    Publication number: 20060094884
    Abstract: Compounds of formula: (1) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Application
    Filed: February 23, 2004
    Publication date: May 4, 2006
    Inventors: Ingemar Starke, Suzanne Alenfalk, Mats Nordberg, Mikael Dahlstrom, Stig Bostrom, Malin Lemurell, Andreas Wallberg
  • Diphenylazetidinone derivatives for treating disorders of the lipid metabolism
    Publication number: 20050239766
    Abstract: Compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Application
    Filed: July 1, 2003
    Publication date: October 27, 2005
    Applicant: AstraZeneca AB
    Inventors: Ingemar Starke, Mikael Dahlstrom, Ann-Margret Lindqvist, Mats Nordberg, Tore Skjaret, Malin Lemurell
  • Peptides derivatives comprising thiazepine group for the treatment of hyperlipidermic conditions
    Publication number: 20050222120
    Abstract: The present invention relates to compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Process for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Application
    Filed: June 10, 2003
    Publication date: October 6, 2005
    Inventors: Ingemar Starke, Mikael Dahlstrom, Suzanne Alenfalk, Tore Skjaret, Malin Lemurell
  • Benzothiazepine and benzothiazepine derivatives with ileal bile acid transport (ibat) inhibitory activity for the treatment hyperlipidaemia
    Publication number: 20050038009
    Abstract: The present invention relates to compounds of formula (I) wherein Rv, R1, R2, Rx, Ry, M, Rz, v, R3, R4, R5 and R6 are as defined within; pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Application
    Filed: September 5, 2002
    Publication date: February 17, 2005
    Inventors: Ingemar Starke, Mikael Dahlstrom, David Blomberg, Suzanne Alenfalk, Tore Skjaret, Malin Lemurell