Patents by Inventor Mamatha Mahadevappa

Mamatha Mahadevappa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for detecting and diagnosing oral cancer
    Patent number: 7108969
    Abstract: Methods of monitoring the expression of genes in malignant oral cells is disclosed. Gene expression profiles are used to identify markers associated with malignant oral cells and to diagnose oral cancer.
    Type: Grant
    Filed: September 10, 2001
    Date of Patent: September 19, 2006
    Assignees: Affymetrix, Inc., President & Fellows of Harvard College
    Inventors: Janet A. Warrington, David T. W. Wong, Charles Randolph Todd, Mamatha Mahadevappa
  • Genes differentially expressed in secretory versus proliferative endometrium
    Publication number: 20050164272
    Abstract: The present invention compares expression profiles from matched samples to identify differential gene expression. Samples are matched according to physiological, pharmacological and/or disease state. Comparison of matched samples eliminates gene expression differences that are the result of changes in variables that are not of interest. The gene expression differences that remain can be attributed with a high degree of confidence to the unmatched variation. The gene expression differences thus identified can be used for example to diagnose disease, identify physiological state, design drugs, and monitor therapies.
    Type: Application
    Filed: January 19, 2005
    Publication date: July 28, 2005
    Applicant: Affymetrix, INC.
    Inventors: Janet Warrington, Mamatha Mahadevappa
  • Genes differentially expressed in secretory versus proliferative endometrium
    Patent number: 6884578
    Abstract: The present invention compares expression profiles from matched samples to identify differential gene expression. Samples are matched according to physiological, pharmacological and/or disease state. Comparison of matched samples eliminates gene expression differences that are the result of changes in variables that are not of interest. The gene expression differences that remain can be attributed with a high degree of confidence to the unmatched variation. The gene expression differences thus identified can be used for example to diagnose disease, identify physiological state, design drugs, and monitor therapies.
    Type: Grant
    Filed: December 11, 2000
    Date of Patent: April 26, 2005
    Assignee: Affymetrix, Inc.
    Inventors: Janet A. Warrington, Mamatha Mahadevappa
  • Methods for identifying and using maintenance genes
    Publication number: 20050053998
    Abstract: This invention provides methods for discovering maintenance genes and for using maintenance genes. In one embodiment, the expression of at least three maintenance genes are measured and used as reference (or control) for comparing the expression of target genes in two or more biological samples.
    Type: Application
    Filed: October 18, 2004
    Publication date: March 10, 2005
    Applicant: Affymetrix, INC.
    Inventors: Janet Warrington, Mamatha Mahadevappa, Archana Nair
  • Methods for identifying and using maintenance genes
    Patent number: 6841348
    Abstract: This invention provides methods for discovering maintenance genes and for using maintenance genes. In one embodiment, the expression of at least three maintenance genes are measured and used as reference (or control) for comparing the expression of target genes in two or more biological samples.
    Type: Grant
    Filed: October 19, 2000
    Date of Patent: January 11, 2005
    Assignee: Affymetrix, Inc.
    Inventors: Janet A. Warrington, Mamatha Mahadevappa, Archana Nair
  • Molecular genetic profiling of gleason grades 3 and 4/5 prostate cancer
    Publication number: 20040029151
    Abstract: Many genes are affected in prostate cancers which have not been previously identified. This includes genes that have been up-regulated or down-regulated. Monitoring the expression levels of these genes is useful to identify the existence of prostate cancer. Also, monitoring the expression levels of these genes is useful to predict the effectiveness of treatment, outcome, use of therapeutics, and screening drugs useful for the treatment of prostate cancer.
    Type: Application
    Filed: April 9, 2003
    Publication date: February 12, 2004
    Applicant: Affymetrix, INC.
    Inventors: Mamatha Mahadevappa, Zhaomei Zhang, Janet A. Warrington, John F. Palma, Mitchell C. Caldwell, Zuxiong Chen, Zhenbin Fan, John E. McNeal, Rosalie Nolley, Thomas A. Stamey
  • Genes defferentially expressed in secretory versus proliferative endometrium
    Publication number: 20010044104
    Abstract: The present invention compares expression profiles from matched samples to identify differential gene expression. Samples are matched according to physiological, pharmacological and/or disease state. Comparison of matched samples eliminates gene expression differences that are the result of changes in variables that are not of interest. The gene expression differences that remain can be attributed with a high degree of confidence to the unmatched variation. The gene expression differences thus identified can be used for example to diagnose disease, identify physiological state, design drugs, and monitor therapies.
    Type: Application
    Filed: December 11, 2000
    Publication date: November 22, 2001
    Inventors: Janet A. Warrington, Mamatha Mahadevappa