Patents by Inventor Mami KOYAMA

Mami KOYAMA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR INCREASING DEPOSITION OF COMPLEMENT C3b ON BACTERIAL SURFACE AND PHAGOCYTOSIS BY PHAGOCYTE AND A THERAPEUTIC METHOD AND A THERAPEUTIC AGENT FOR BACTERIAL INFECTIONS
    Publication number: 20140212409
    Abstract: The present invention relates to a method for increasing deposition of complement C3b on the bacterial surface and phagocytosis by phagocytes, a therapeutic method and a therapeutic agent for bacterial infections, using an antibody binding to a molecule on the bacterial surface, in which the antibody is modified by substituting at least one amino acid residue with other amino acid so as to show more enhanced complement-dependent cytotoxicity (CDC) than the antibody before substitution of the amino acid residue.
    Type: Application
    Filed: August 13, 2013
    Publication date: July 31, 2014
    Applicant: KYOWA HAKKO KIRIN CO., LTD.
    Inventors: Sascha KRISTIAN, Mami KOYAMA, Yutaka KANDA, Tomoyuki TAHARA