Patents by Inventor Mamoru Kunishima

Mamoru Kunishima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4495348
    Abstract: Disclosed are an N-benzenesulfonyl derivative of cephamycin C represented by the following formula: ##STR1## which can easily be separated as a solid from an aqueous solution thereof, and a process for the preparation thereof.This derivative is valuable as an intermediate leading to a cephamycin type antibiotic substance.
    Type: Grant
    Filed: November 24, 1981
    Date of Patent: January 22, 1985
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Mamoru Kunishima, Masahiko Yabuuchi, Minoru Masuda, Kikuo Imazumi, Hiroaki Hamano
  • Patent number: 4326054
    Abstract: Novel antibiotics cleomycins represented by the formula ##STR1## wherein R is a terminal amino residue of the cleomycin. These compounds are useful as a chemotherapeutic agent for treating cancer and bacterial infections.
    Type: Grant
    Filed: July 9, 1980
    Date of Patent: April 20, 1982
    Assignee: Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
    Inventors: Hamao Umezawa, Tomohisa Takita, Akio Fujii, Yasuhiko Muraoka, Mamoru Kunishima
  • Patent number: 4233224
    Abstract: Anti-tumor low-toxicity coriolin derivatives represented by the following general formula: ##STR1## wherein one of X and Y is ##STR2## and the other is >C OH, >C.dbd.
    Type: Grant
    Filed: May 23, 1979
    Date of Patent: November 11, 1980
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Yuya Nakayama, Mamoru Kunishima, Akira Matsuda, Tomio Takeuchi
  • Patent number: 4190589
    Abstract: Coriolin derivatives having antitumor activity and low toxicity represented by the following general formula: ##STR1## where R: --CO(CH.sub.2).sub.6 CH.sub.3 or --COCH(OH)(CH).sub.2).sub.5 CH.sub.3,X: .dbd.CH.sub.2 or --COOR',R': H or lower alkyl group.Y: OH or .dbd.O andZ: --OH or OCH.sub.3,as well as the process for producing the above derivatives are disclosed.
    Type: Grant
    Filed: May 4, 1978
    Date of Patent: February 26, 1980
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Yuya Nakayama, Mamoru Kunishima, Akira Matsuda, Tomio Takeuchi, Hamao Umezawa