Abstract: This invention provides an all-in-one device for virus diagnosis, especially for a target nucleic acid sequence or target antigens or anitbodies in a single sample, comprising: a sample chamber for holding a cuvette with a UCNP-based assay and said sample; a NIR light source; a sensor for measuring fluorescence emission from a UCNP-based assay comprising a light-to-frequency converter; Optics providing an optical path ensuring only fluorescence emission from said UCNP-based assay reaches said sensor; and a microcontroller; wherein said UCNP-based assay is a system comprising UCNP surface modified with a first oligo probe and AuNP surface modified with a second oligo probe, wherein said first oligo probe and said second oligo probe are independently complimentary to separate segments on said target nucleic acid sequence that are nearby each other; or/and a system comprising ligand-free UCNP with electrostatic attraction to said target protein and AuNR surface modified with antibodies for said target protein.

Abstract: The synthesis and characterization of a platinum (II) terpyridine system tethered with a latent organic dye of rhodamine derivative as colorimetric and fluorescent sensory moiety has been reported to show selective Hg2+ ion sensing behavior. The interplay of aggregation/de-aggregation behavior of the alkynylplatinum(II) terpyridine complex and the ring-opening process of rhodamine derivative has been investigated. The spectral change of aggregation NIR emission at 800 nm and rhodamine fluorescence at 585 nm provides a possible ratiometric luminescence measurement. Morphological studies from TEM and SEM images showing nanospherical structures confirmed the aggregation in the absence of Hg2+ ion.

Abstract: Disclosed are a parallel multi-converter and a capacity design method therefor. A first output current model and a second output current model are generated by respectively acquiring electrical parameters of an inductive voltage source converter and a capacitive voltage source converter, and the first output current model and the second output current model are integrated under the same output current condition, so that it may be ensured that the inductive voltage source converter and the capacitive voltage source converter have the same current generating ability; meanwhile, a coupling inductance relationship between the inductive voltage source converter and the capacitive voltage source converter is combined to further obtain the optimal capacity value of the inductive voltage source converter and the optimal capacity value of the capacitive voltage source converter. Therefore, the L-VSC and the LC-VSC have the same current generating ability, and the multi-converter has lower total voltage capacity.

Abstract: A series of highly luminescent cyclometalated rhodium(III) complexes, with photoluminescence quantum yields up to 0.65 in thin films, have been designed and prepared. The strong luminescence property is realized by the judicious choice of a strong ?-donor cyclometalating ligand with lower-lying intraligand state and the ability to raise the d-d excited state. This is the first report to demonstrate the capability of rhodium(III) complexes as high efficient light-emitting materials for organic light-emitting devices. Compelling external quantum efficiencies of up to 12.2% and operational half-lifetime of over 3,000 hours have been achieved.

Abstract: Through the use of a rhodamine appended chelate, a versatile strategy has been demonstrated to generate mitochondria-targeting photosensitizers via the incorporation of variety of luminescent transition metal systems. The generation of triplet excited state of rhodamine moiety endows the complexes with mitochondria-targeting photosensitizing ability to form singlet oxygen (1O2) for use as photodynamic therapy (PDT) agent. The combination of rhodamine organic dye and luminescent transition metal centers in such hybrid systems exhibits the synergistic merits, including low dark cytotoxicity, selective tumor cell uptake, high molar absorptivity for low-energy excitation in the visible region, and high photostability.

Abstract: The synthesis and characterization of a platinum (II) terpyridine system tethered with a latent organic dye of rhodamine derivative as colorimetric and fluorescent sensory moiety has been reported to show selective Hg2+ ion sensing behavior. The interplay of aggregation/de-aggregation behavior of the alkynylplatinum(II) terpyridine complex and the ring-opening process of rhodamine derivative has been investigated. The spectral change of aggregation NIR emission at 800 nm and rhodamine fluorescence at 585 nm provides a possible ratiometric luminescence measurement. Morphological studies from TEM and SEM images showing nanospherical structures confirmed the aggregation in the absence of Hg2+ ion.

Abstract: Through the use of a rhodamine appended chelate, a versatile strategy has been demonstrated to generate mitochondria-targeting photosensitizers via the incorporation of variety of luminescent transition metal systems. The generation of triplet excited state of rhodamine moiety endows the complexes with mitochondria-targeting photosensitizing ability to form singlet oxygen (1O2) for use as photodynamic therapy (PDT) agent. The combination of rhodamine organic dye and luminescent transition metal centers in such hybrid systems exhibits the synergistic merits, including low dark cytotoxicity, selective tumor cell uptake, high molar absorptivity for low-energy excitation in the visible region, and high photostability.

Abstract: A method for inhibiting the expression and/or functional activity of an ABC transporter protein in a subject suffering from a disorder associated with an overexpression of the ABC transporter protein includes administrating a cobalt-polypyridyl complex to the subject. A method for inhibiting the expression and/or functional activity of an ABC transporter in cells includes contacting the cells with an effective amount of the cobalt-polypyridyl complex.

Abstract: A hybrid-STATCOM for providing compensating reactive power required by a load, the hybrid-STATCOM comprising: a TCLC part for each electric power phase, each TCLC part comprising: a coupling inductor; a power filter capacitor; and a thyristor-controlled reactor connected in series with a power filter inductor; and an active inverter part comprising: a voltage source inverter for each electric power phase; and a DC-link capacitor connected in parallel with the voltage source inverters. The control strategy of the hybrid-STATCOM is separated into two parts: TCLC part control and Active inverter part control. The TCLC part control is based on the instantaneous pq theory and aims to compensate the loading reactive power with the controllable TCLC part impedance. The active inverter part control is based on the instantaneous active and reactive current id-iq method and aims to improve the overall performance of the hybrid-STATCOM under different voltage and current conditions.

Abstract: A thyristor controlled LC (TCLC) compensator for compensating dynamic reactive power in a power grid system, with an advantage of mitigating harmonic current injection from solid-state switches during switching on or off is provided. Exemplarily, the TCLC compensator is shunt-connected to the three-phase power grid and comprises an electronic controller, a coupling inductor (Lc), a first branch of circuit with a parallel inductor (LPF) and a solid-state switch, and a second branch of circuit with a parallel capacitor (CPF), wherein the coupling inductor (Lc) is connected in series with a parallel combination of the first and second branch of circuit. The electronic controller for the TCLC compensator is configured in accordance to the generalized instantaneous reactive power theory for improving the response speed instead of using traditional average reactive power concept.

Abstract: A method for treating a subject suffering from a cancer, in particular a multidrug-resistant cancer includes administrating a cobalt-polypyridyl complex to the subject. A method for suppressing the growth of cancer cells, in particular inducing autophagy of the cancer cells, inducing cell cycle arrest of the cancer cells and/or inhibiting cell invasion of the cancer cells and for specifically targeting cancer cells with multidrug-resistance includes contacting said cancer cells with the cobalt-polypyridyl complex. A pharmaceutical composition and a kit are provided and include the cobalt-polypyridyl complex. Unexpectedly, the cobalt-polypyridyl complex is especially suitable to treat cancer, in particular multidrug-resistant cancer with an exceptionally increased cytotoxic activity towards multidrug-resistant cancer cells.

Abstract: A method for inhibiting the expression and/or functional activity of an ABC transporter protein in a subject suffering from a disorder associated with an overexpression of the ABC transporter protein includes administrating a cobalt-polypyridyl complex to the subject. A method for inhibiting the expression and/or functional activity of an ABC transporter in cells includes contacting the cells with an effective amount of the cobalt-polypyridyl complex.

Abstract: A method for treating a subject suffering from a cancer, in particular a multidrug-resistant cancer includes administrating a cobalt-polypyridyl complex to the subject. A method for suppressing the growth of cancer cells, in particular inducing autophagy of the cancer cells, inducing cell cycle arrest of the cancer cells and/or inhibiting cell invasion of the cancer cells and for specifically targeting cancer cells with multidrug-resistance includes contacting said cancer cells with the cobalt-polypyridyl complex. A pharmaceutical composition and a kit are provided and include the cobalt-polypyridyl complex. Unexpectedly, the cobalt-polypyridyl complex is especially suitable to treat cancer, in particular multidrug-resistant cancer with an exceptionally increased cytotoxic activity towards multidrug-resistant cancer cells.

Abstract: A mixed signal controller for a power quality compensator includes an analog circuit, an analog-to-digital converter (ADC), and a digital circuit. The analog circuit amplifies an input signal from the power quality compensator by a gain factor and outputs an analog signal, which is converted to a digital signal by the ADC. The digital circuit receives the digital signal, calculates the reference compensating current of each phase and then generates a trigger signal via hysteresis PWM to the power quality compensator. The digital circuit includes an evaluation circuit that calculates a value of the system total harmonic distortion after the power quality compensator compensates power and adjusts the gain factor when the value of the system total harmonic distortion reaches a predetermined threshold.

Abstract: A mixed signal controller for a power quality compensator includes an analog circuit, an analog-to-digital converter (ADC), and a digital circuit. The analog circuit amplifies an input signal from the power quality compensator by a gain factor and outputs an analog signal, which is converted to a digital signal by the ADC. The digital circuit receives the digital signal, calculates the reference compensating current of each phase and then generates a trigger signal via hysteresis PWM to the power quality compensator. The digital circuit includes an evaluation circuit that calculates a value of the system total harmonic distortion after the power quality compensator compensates power and adjusts the gain factor when the value of the system total harmonic distortion reaches a predetermined threshold.

Abstract: A novel class of saturated or conjugated dendrimers containing at least one strong ?-donating group coordinated to cyclometalated tridentate gold(III) compounds having the chemical structure depicted by generic formula: wherein: (a) [Au] is a cyclometalated tridentate gold(III) group; (b) Unit A is a ?-donating chemical group; (c) Unit B is a central part of the dendrons comprising a branch point of component dendrimers; (d) Unit C is optional surface groups or dendrons of the dendrimers; (e) n=0 or 1.

Abstract: An adaptive dc-link voltage controlled LC coupling hybrid active power filter (LC-HAPF) for reactive power compensation includes: two dc capacitors to provide dc-link voltage; a three-phase voltage source inverter to convert dc-link voltage into compensating voltages; three coupling LC circuits to convert compensating voltages into currents; and an adaptive dc voltage controller with reactive power compensation control algorithm. The control algorithm includes: first, calculating required minimum dc-link voltage in each phase with respect to loading reactive power; three-phase required minimum dc-link voltage will be maximum one among their minimum values; compare it with predetermined voltage levels to determine final reference dc-link voltage. A dc-link voltage feedback P/PI controller outputs dc voltage reference compensating currents. An instantaneous power compensation controller outputs reactive reference compensating currents. The final reference compensating currents will be sum of them.

Abstract: In one embodiment, the present invention provides a class of luminescent gold(III) compounds containing a tridentate ligand with one strong ?-donating group. The present invention also provides methods for synthesizing these compounds, as well as uses of these compounds as electrophosphorescent materials in phosphorescent organic light-emitting devices (OLEDs) to provide electroluminescence (EL).

Abstract: A railway power conditioner includes a DC-AC converter and a AC-DC converter for performing power conversion between AC power and DC power, a DC bus connected between the DC-AC converter and the AC-DC converter; a single-phase isolation transformer coupled to an output of the AC-DC converter and a coupling capacitor connected to the DC-AC converter.

Abstract: An adaptive dc-link voltage controlled LC coupling hybrid active power filter (LC-HAPF) for reactive power compensation includes: two dc capacitors to provide dc-link voltage; a three-phase voltage source inverter to convert dc-link voltage into compensating voltages; three coupling LC circuits to convert compensating voltages into currents; and an adaptive dc voltage controller with reactive power compensation control algorithm. The control algorithm includes: first, calculating required minimum dc-link voltage in each phase with respect to loading reactive power; three-phase required minimum dc-link voltage will be maximum one among their minimum values; compare it with predetermined voltage levels to determine final reference dc-link voltage. A dc-link voltage feedback P/PI controller outputs dc voltage reference compensating currents. An instantaneous power compensation controller outputs reactive reference compensating currents. The final reference compensating currents will be sum of them.