Patents by Inventor Man Iu LAM

Man Iu LAM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combinations and methods comprising a capsid assembly inhibitor
    Patent number: 11129834
    Abstract: The present disclosure is directed to capsid assembly inhibitor compositions and methods for use in the treatment of hepatitis B virus infection.
    Type: Grant
    Filed: August 15, 2019
    Date of Patent: September 28, 2021
    Assignees: Novira Therapeutics, Inc., Janssen Sciences Ireland Unlimited Company
    Inventors: George Hartman, Osvaldo Flores, Klaus Klumpp, Man Iu Lam, Jan Martin Berke
  • COMBINATIONS AND METHODS COMPRISING A CAPSID ASSEMBLY INHIBITOR
    Publication number: 20190365767
    Abstract: The present disclosure is directed to capsid assembly inhibitor compositions and methods for use in the treatment of hepatitis B virus infection.
    Type: Application
    Filed: August 15, 2019
    Publication date: December 5, 2019
    Inventors: George Hartman, Osvaldo Flores, Klaus Klumpp, Man Iu Lam, Jan Martin Berke
  • Combinations and methods comprising a capsid assembly inhibitor
    Patent number: 10441589
    Abstract: The present disclosure is directed to capsid assembly inhibitor compositions and methods for use in the treatment of hepatitis B virus infection.
    Type: Grant
    Filed: April 14, 2017
    Date of Patent: October 15, 2019
    Assignees: NOVIRA THERAPEUTICS, INC., Janssen Sciences Ireland Unlimited Company
    Inventors: George Hartman, Osvaldo Flores, Klaus Klumpp, Man Iu Lam, Jan Martin Berke
  • METABOLIC RESTRICTION IN CELL-BASED ASSAYS
    Publication number: 20190234940
    Abstract: Provided are methods and assays used in the screening and identification of agents in assays that use metabolically active cells.
    Type: Application
    Filed: October 2, 2017
    Publication date: August 1, 2019
    Inventors: Man Iu LAM, Christine Lisa ESPIRITU, Scott KUDUK, George D. HARTMAN
  • COMBINATIONS AND METHODS COMPRISING A CAPSID ASSEMBLY INHIBITOR
    Publication number: 20170340642
    Abstract: The present disclosure is directed to capsid assembly inhibitor compositions and methods for use in the treatment of hepatitis B virus infection.
    Type: Application
    Filed: April 14, 2017
    Publication date: November 30, 2017
    Inventors: George HARTMAN, Osvaldo FLORES, Klaus KLUMPP, Man Iu LAM, Jan Martin BERKE
  • CRYSTAL STRUCTURE OF HCV POLYMERASE COMPLEXES AND METHODS OF USE
    Publication number: 20150087045
    Abstract: The present disclosure includes a crystalline form and a crystal structure of HCV RNA polymerase and HCV RNA polymerase in a complex with an RNA template primer molecule. In other aspects, the disclosure provides methods of using the crystal structures and structural coordinates to identify homologous proteins and to design or identify agents that can modulate the function of the HCV RNA polymerase and HCV RNA polymerase in a complex with an RNA template primer molecule.
    Type: Application
    Filed: January 11, 2013
    Publication date: March 26, 2015
    Inventors: Thomas E. Edwards, Angela Man Iu Lam, Ralph T. Mosley, Eisuke Murakami
  • Compounds and methods for treatment of HCV
    Publication number: 20090041723
    Abstract: Aryl substituted pyrazole derivatives are provided, as well as processes for their preparation. The invention also provides compositions and methods for the treatment of HCV by administering a compound of the present invention, alone or in combination with additional antiviral agents, in a therapeutically effective amount.
    Type: Application
    Filed: October 15, 2007
    Publication date: February 12, 2009
    Inventors: Guolin Li, Reza Fathi, Zhen Yang, Yun Liao, Qiang Zhu, Angela Man Iu Lam, Anthony Sandrasagra, Kenneth Nawoschik, Hyun-Joon Cho, Jie Cao, Wu Rouqiu, C. Richard Wobbe