Abstract: A photocatalytic coating composition and method of coating articles, the composition containing solvents for rapid evaporation at room temperature, polyalkylphenylsiloxane, xylene, nano densified hydrophilic fumed silica, nanostructured composite photocatalyst powder and nano inorganic anti-bacteria powder. The coating may be applied by conventional coating methods to organic or inorganic structured surfaces where photocatalytic activity is desired, such as in a forced air-circulating environment. Once applied, the coating quickly dries to leave an adherent, flexible, durable, and long-lasting photocatalytic coating having a large surface area and exhibiting high surface activity against pathogens and pollutants such as bacteria, viruses, mold, fungi, and volatile organic compounds.