Patents by Inventor Manmohan Singh
Manmohan Singh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230398203Abstract: Influenza vaccines are administered using solid biodegradable microneedles. The microneedles are lubricated from the influenza vaccine in combination with solid excipient(s) and, after penetrating the skin, they dissolve in situ and release the vaccine to the immune system. The influenza vaccine is (i) a purified influenza virus surface antigen vaccine, rather than a live vaccine or a whole-virus or split inactivated vaccine (ii) an influenza vaccine prepared from viruses grown in cell culture, not eggs, (iii) a monovalent influenza vaccine e.g. for immunising against a pandemic strain, (iv) a bivalent vaccine, (v) a tetravalent or >4 -valent vaccine, (vi) mercury-free vaccine, or (vii) a gelatin-free vaccine.Type: ApplicationFiled: October 11, 2022Publication date: December 14, 2023Inventors: Derek O'HAGAN, Manmohan SINGH, Sung-Yun KWON
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Patent number: 11839483Abstract: Methods and systems for providing depth-resolved real-time visual feedback to a physician during cosmetic dermal filler injections with micrometer spatial resolution utilizing a noninvasive optical coherence tomography/elastography, 2D-3D virtual and real time system. This system can be automated to direct proper volumes and viscosity of the necessary injection substances. The methods and systems allow for assessment of the elasticity of the tissue before and after the injection to evaluate the efficacy of the injection, with predetermined virtual results before and matched post injection images. The elasticity assessment method preferably utilizes a focused air-pulse to induce a micrometer scale displacement in the skin and the optical coherence tomography system to image this displacement. By utilizing a model-based reconstruction method, the viscoelasticity of the tissue at a specific measurement position can be obtained and virtual and post injection real time projections can be imaged.Type: GrantFiled: August 25, 2016Date of Patent: December 12, 2023Assignee: UNIVERSITY OF HOUSTON SYSTEMInventors: Kirill Larin, Richard Yee, Manmohan Singh
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Patent number: 11823065Abstract: Aspects of the disclosure relate to using synthetic DNA stranding and mutant nucleotide processes to conduct enterprise market volatility predictions. In some embodiments, a computing platform may receive raw market data from a plurality of lines of business of an enterprise organization. Thereafter, the computing platform may preprocess the raw market data to obtain enterprise level market data, execute synthetic DNA stranding of the enterprise level market data to obtain synthetic DNA stranded market data, run the synthetic DNA stranded market data through one or more market volatility models, and compile results from the market volatility models on the synthetic DNA stranded market data. The computing platform may transmit results from the market volatility models on the synthetic DNA stranded market data. The transmitted results may be configured to display a market application interface that includes market volatility forecasting parameters based on results of the market volatility models.Type: GrantFiled: May 28, 2021Date of Patent: November 21, 2023Assignee: Bank of America CorporationInventors: Manmohan Singh, Shantanu Singh, Vineet Kumar Upadhyay, Madhusudhanan Krishnamoorthy, Amit Ohri, Ruchi Mathur, Kapil Juneja, Karishma Prithviraj Pamnani, Yudhit Mehta
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Patent number: 11823066Abstract: Aspects of the disclosure relate to using synthetic DNA stranding and mutant nucleotide processes to conduct enterprise market volatility predictions. In some embodiments, a computing platform may receive market data from a plurality of lines of business across an enterprise, wherein the market data is received in a raw, uncompressed format. Thereafter, the computing platform may assimilate and preprocess the market data to output vectored market data. The computing platform may perform a synthetic DNA stranding process on the vectored market data to create one or more strands of synthetic DNA market data, and output the one or more strands of synthetic DNA market data to a synthetic DNA client server, wherein the one or more stands of synthetic DNA market data is configured for input in a market volatility prediction model.Type: GrantFiled: May 28, 2021Date of Patent: November 21, 2023Assignee: Bank of America CorporationInventors: Manmohan Singh, Shantanu Singh, Vineet Kumar Upadhyay, Madhusudhanan Krishnamoorthy, Amit Ohri, Ruchi Mathur, Kapil Juneja, Karishma Prithviraj Pamnani, Yudhit Mehta
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Patent number: 11823064Abstract: Aspects of the disclosure relate to using synthetic DNA stranding and mutant nucleotide processes to conduct enterprise market volatility predictions. In some embodiments, a computing platform may initiate a set of instructions associated with performing an action on a synthetic DNA market data set associated with a plurality of lines of business across an enterprise organization. Thereafter, the computing platform may convert the set of instructions to a mutant nucleotide sequence, and insert the mutant nucleotide sequence into the synthetic DNA market data set. The computing platform may extract, using the mutant nucleotide sequence, target information from the synthetic DNA market data set, and validate the target information to detect one or more anomalies. The computing platform may remove the one or more data anomalies, and subsequently output a validated synthetic DNA market data set to a synthetic DNA client server.Type: GrantFiled: May 28, 2021Date of Patent: November 21, 2023Assignee: Bank of America CorporationInventors: Manmohan Singh, Shantanu Singh, Vineet Kumar Upadhyay, Madhusudhanan Krishnamoorthy, Amit Ohri, Ruchi Mathur, Kapil Juneja, Karishma Prithviraj Pamnani, Yudhit Mehta
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Publication number: 20230314197Abstract: Certain embodiments of the present disclosure relate to a sensor assembly including a substrate, a housing, and a sensor die. In certain embodiments, the substrate includes an outer region, an inner region, and a middle region between the outer region and the inner region. In certain embodiments, the substrate includes electrical contact pads on at least the inner region. In certain embodiments, the housing is coupled to the substrate at the middle region or the outer region to provide a hermetic seal. In certain embodiments, the sensor die is coupled to the substrate at the inner region via the electrical contact pads. The sensor die is aligned to the substrate via aligning features that align the sensor die relative to the substrate in at least one of a first plane or a second plane.Type: ApplicationFiled: June 30, 2022Publication date: October 5, 2023Inventors: Arvinder Manmohan Singh Chadha, Ashley M. Okada, Srikanth Krishnamurthy, Ming Xu
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Patent number: 11723529Abstract: A system and method for measuring biomechanical properties of tissues without external excitation are capable of measuring and quantifying these parameters of tissues in situ and in vivo. The system and method preferably utilize a phase-sensitive optical coherence tomography (OCT) system for measuring the displacement caused by the intrinsic heartbeat. The method allows noninvasive and nondestructive quantification of tissue mechanical properties. Preferably, the method is used to detect tissue stiffness and to evaluate its stiffness due to intrinsic pulsatile motion from the heartbeat. This noninvasive method can evaluate the biomechanical properties of the tissues in vivo for detecting the onset and progression of degenerative or other diseases and evaluating the efficacy of therapies.Type: GrantFiled: August 8, 2022Date of Patent: August 15, 2023Assignee: UNIVERSITY OF HOUSTON SYSTEMInventors: Kirill V. Larin, Achuth Nair, Manmohan Singh, Salavat Aglyamov
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Publication number: 20230210371Abstract: Provided herein are systems and methods to measure the intraocular pressure, ocular tissue geometry and the biomechanical properties of an ocular tissue, such as an eye-globe or cornea, in one instrument. The system is an optical coherence tomography subsystem and an applanation tonometer subsystem housed as one instrument and interfaced with a computer for at least data processing and image display. The system utilizes an air-puff and a focused micro air-pulse to induce deformation and applanation and displacement in the ocular tissue. Pressure profiles of the air puff with applanation times are utilized to measure intraocular pressure. Temporal profiles of displacement and/or spatio-temporal profiles of a displacement-generated elastic wave are analyzed to calculate biomechanical properties.Type: ApplicationFiled: December 1, 2022Publication date: July 6, 2023Applicant: University of Houston SystemInventors: Kirill V. Larin, Manmohan Singh, Jiasong Li, Zhaolong Han, Michael D. Twa
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Publication number: 20230119950Abstract: The present disclosure generally relates to a system and method for providing audio and image data. The system and method may receive blurbs from users that include audio and image data. The exemplary disclosed system and method may prioritize or push a given blurb based on consumption by other users. The exemplary disclosed system and method may further prioritize or push a given blurb based on an aggregate metric based on consumption and engagement by other users.Type: ApplicationFiled: October 19, 2022Publication date: April 20, 2023Inventors: Eriz Gonzales De Zarate Lopez, Mohammad Aladham, Manmohan Singh Balbir Singh
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Patent number: 11553839Abstract: Provided herein are systems and methods to measure the intraocular pressure, ocular tissue geometry and the biomechanical properties of an ocular tissue, such as an eye-globe or cornea, in one instrument. The system is an optical coherence tomography subsystem and an applanation tonometer subsystem housed as one instrument and interfaced with a computer for at least data processing and image display. The system utilizes an air-puff and a focused micro air-pulse to induce deformation and applanation and displacement in the ocular tissue. Pressure profiles of the air puff with applanation times are utilized to measure intraocular pressure. Temporal profiles of displacement and/or spatio-temporal profiles of a displacement-generated elastic wave are analyzed to calculate biomechanical properties.Type: GrantFiled: December 21, 2018Date of Patent: January 17, 2023Assignee: UNIVERSITY OF HOUSTON SYSTEMInventors: Kirill V. Larin, Manmohan Singh, Jiasong Li, Zhaolong Han, Michael D. Twa
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Publication number: 20220386862Abstract: A system and method for measuring biomechanical properties of tissues without external excitation are capable of measuring and quantifying these parameters of tissues in situ and in vivo. The system and method preferably utilize a phase-sensitive optical coherence tomography (OCT) system for measuring the displacement caused by the intrinsic heartbeat. The method allows noninvasive and nondestructive quantification of tissue mechanical properties. Preferably, the method is used to detect tissue stiffness and to evaluate its stiffness due to intrinsic pulsatile motion from the heartbeat. This noninvasive method can evaluate the biomechanical properties of the tissues in vivo for detecting the onset and progression of degenerative or other diseases and evaluating the efficacy of therapies.Type: ApplicationFiled: August 8, 2022Publication date: December 8, 2022Applicant: University of Houston SystemInventors: Kirill V. Larin, Achuth Nair, Manmohan Singh, Salavat Aglyamov
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Publication number: 20220390108Abstract: An improved and high capacity gas igniter for furnaces and burners. The igniter can include an igniter tip that is annular in shape and includes various holes of different sizes and angular projections distributed throughout. The igniter tip may utilize a slip-joint-like mechanism or sleeve that connects inner and outer tubes of a guide tube that allows the inner tube to slide when undergoing thermal expansion. This configuration alleviates stress from building up on the inner tube and igniter tip, preventing damage.Type: ApplicationFiled: June 8, 2021Publication date: December 8, 2022Applicant: Forney CorporationInventors: Mahmoud Fleifil, Manmohan Singh
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Publication number: 20220383136Abstract: Aspects of the disclosure relate to using synthetic DNA stranding and mutant nucleotide processes to conduct enterprise market volatility predictions. In some embodiments, a computing platform may receive raw market data from a plurality of lines of business of an enterprise organization. Thereafter, the computing platform may preprocess the raw market data to obtain enterprise level market data, execute synthetic DNA stranding of the enterprise level market data to obtain synthetic DNA stranded market data, run the synthetic DNA stranded market data through one or more market volatility models, and compile results from the market volatility models on the synthetic DNA stranded market data. The computing platform may transmit results from the market volatility models on the synthetic DNA stranded market data. The transmitted results may be configured to display a market application interface that includes market volatility forecasting parameters based on results of the market volatility models.Type: ApplicationFiled: May 28, 2021Publication date: December 1, 2022Inventors: Manmohan Singh, Shantanu Singh, Vineet Kumar Upadhyay, Madhusudhanan Krishnamoorthy, Amit Ohri, Ruchi Mathur, Kapil Juneja, Karishma Prithviraj Pamnani, Yudhit Mehta
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Publication number: 20220383135Abstract: Aspects of the disclosure relate to using synthetic DNA stranding and mutant nucleotide processes to conduct enterprise market volatility predictions. In some embodiments, a computing platform may initiate a set of instructions associated with performing an action on a synthetic DNA market data set associated with a plurality of lines of business across an enterprise organization. Thereafter, the computing platform may convert the set of instructions to a mutant nucleotide sequence, and insert the mutant nucleotide sequence into the synthetic DNA market data set. The computing platform may extract, using the mutant nucleotide sequence, target information from the synthetic DNA market data set, and validate the target information to detect one or more anomalies. The computing platform may remove the one or more data anomalies, and subsequently output a validated synthetic DNA market data set to a synthetic DNA client server.Type: ApplicationFiled: May 28, 2021Publication date: December 1, 2022Inventors: Manmohan Singh, Shantanu Singh, Vineet Kumar Upadhyay, Madhusudhanan Krishnamoorthy, Amit Ohri, Ruchi Mathur, Kapil Juneja, Karishma Prithviraj Pamnani, Yudhit Mehta
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Publication number: 20220383137Abstract: Aspects of the disclosure relate to using synthetic DNA stranding and mutant nucleotide processes to conduct enterprise market volatility predictions. In some embodiments, a computing platform may receive market data from a plurality of lines of business across an enterprise, wherein the market data is received in a raw, uncompressed format. Thereafter, the computing platform may assimilate and preprocess the market data to output vectored market data. The computing platform may perform a synthetic DNA stranding process on the vectored market data to create one or more strands of synthetic DNA market data, and output the one or more strands of synthetic DNA market data to a synthetic DNA client server, wherein the one or more stands of synthetic DNA market data is configured for input in a market volatility prediction model.Type: ApplicationFiled: May 28, 2021Publication date: December 1, 2022Inventors: Manmohan Singh, Shantanu Singh, Vineet Kumar Upadhyay, Madhusudhanan Krishnamoorthy, Amit Ohri, Ruchi Mathur, Kapil Juneja, Karishma Prithviraj Pamnani, Yudhit Mehta
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Publication number: 20220329901Abstract: An electronic apparatus is provided. The electronic apparatus includes: a display; and a processor configured to: control the display to display a content based on one mode of a plurality of display modes, receive a user voice in real time while the content is being displayed, identify user's age information corresponding to the received user voice, identify whether or not the one mode is a kids mode when the identified user's age information is less than a threshold value, and change the one mode to the kids mode when it is identified that the one mode is not the kids mode.Type: ApplicationFiled: July 27, 2021Publication date: October 13, 2022Applicant: SAMSUNG ELECTRONICS CO., LTD.Inventor: Manmohan Singh BOHARA
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Patent number: 11422927Abstract: Systems, computer program products, and methods are described herein for testing application resiliency via context aware auditing equilibrium. The present invention is configured to receive an indication to test application resiliency of an application; initiate a resiliency test engine on the application; determine, using the resiliency test engine, one or more artifacts associated with the application to be tested; determine a first subset of the one or more test scripts is able to capture a behavior of a first subset of the one or more artifacts; initiate a context-based classification engine on the first subset of the one or more test scripts and the first subset of the one or more artifacts; classify the first subset of the one or more test scripts into a supporting behavior class and an opposing behavior class; generate a graphical representation of the classification; and display the graphical representation of the classification.Type: GrantFiled: June 4, 2021Date of Patent: August 23, 2022Assignee: BANK OF AMERICA CORPORATIONInventors: Madhusudhanan Krishnamoorthy, Sreekanth Raghuveer Maringanti, Manmohan Singh, Sudhir Kumar Biswal
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Patent number: 11406258Abstract: A system and method for measuring biomechanical properties of tissues without external excitation are capable of measuring and quantifying these parameters of tissues in situ and in vivo. The system and method preferably utilize a phase-sensitive optical coherence tomography (OCT) system for measuring the displacement caused by the intrinsic heartbeat. The method allows noninvasive and nondestructive quantification of tissue mechanical properties. Preferably, the method is used to detect tissue stiffness and to evaluate its stiffness due to intrinsic pulsatile motion from the heartbeat. This noninvasive method can evaluate the biomechanical properties of the tissues in vivo for detecting the onset and progression of degenerative or other diseases and evaluating the efficacy of therapies.Type: GrantFiled: June 22, 2020Date of Patent: August 9, 2022Assignee: UNIVERSITY OF HOUSTON SYSTEMInventors: Kirill V. Larin, Achuth Nair, Manmohan Singh, Salavat Aglyamov
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Patent number: 11369261Abstract: An excitation force (internal or external) and phase-sensitive optical coherence elastography (OCE) system, used in conjunction with a data analyzing algorithm, is capable of measuring and quantifying biomechanical parameters of tissues in situ and in vivo. The method was approbated and demonstrated on an example of the system that combines a pulsed ultrasound system capable of producing an acoustic radiation force on the crystalline lens surface and a phase-sensitive optical coherence tomography (OCT) system for measuring the lens displacement caused by the acoustic radiation force. The method allows noninvasive and nondestructive quantification of tissue mechanical properties. The noninvasive measurement method also utilizes phase-stabilized swept source optical coherence elastography (PhS-SSOCE) to distinguish between tissue stiffness, such as that attributable to disease, and effects on measured stiffness that result from external factors, such as pressure applied to the tissue.Type: GrantFiled: September 3, 2019Date of Patent: June 28, 2022Assignee: UNIVERSITY OF HOUSTON SYSTEMInventors: Kirill V. Larin, Jiasong Li, Manmohan Singh, Chen Wu, Salavat Aglyamov
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Publication number: 20220192997Abstract: Nucleic acid immunisation is achieved by delivering a self-replicating RNA encapsulated within a small particle. The RNA encodes an immunogen of interest, and the particle may deliver this RNA by mimicking the delivery function of a natural RNA virus. Thus the invention provides a non-virion particle for in vivo delivery of RNA to a vertebrate cell, wherein the particle comprises a delivery material encapsulating a self-replicating RNA molecule which encodes an immunogen. These particles are useful as components in pharmaceutical compositions for immunising subjects against various diseases.Type: ApplicationFiled: March 1, 2022Publication date: June 23, 2022Applicant: GLAXOSMITHKLINE BIOLOGICALS SAInventors: Andrew GEALL, Christian Walter MANDL, Derek Thomas O'HAGAN, Manmohan SINGH