Abstract: Methods and compositions for treating liver cancer in a subject in need thereof are provided. Pharmaceutical compositions including an effective amount of an NMDAR inhibitor in combination with a kinase inhibitor and methods of use thereof for treating cancer are disclosed. Administration of the combination of the active agents can be effective to reduce cancer cell proliferation or viability in a subject with cancer to the same degree, or a greater degree than administering to the subject the same amount of either active agent alone. The active agents can be administered together or separately. Methods of selecting and treating subjects with cancers, particular hepatocellular carcinoma are also provided.

Abstract: A computer-implemented method for managing operation of an application includes: authenticating a user of the application or a user device associated with a user of the application; and establishing a session with the application and enabling access to the application for the user if the user or the user device is authenticated. The method further includes determining, after the user or the user device is authenticated, whether the user or the user device is or remains present. The method further includes maintaining the session and the enabling of access to the application if it is determined that the user or the user device is or remains present; and terminating the session and disabling access to the application if it is determined that the user or the user device is absent for a predetermined duration.

Abstract: A computer-implemented method for training a natural language translation model. The computer-implemented method includes: processing one or more sets of electronic parallel documents to obtain a plurality of aligned parallel sentences; creating a first training set including a subset of the plurality of aligned parallel sentences; and training the natural language translation model in a first stage using the first training set. The computer-implemented method further includes: modifying the first training set based on translation errors detected after the first stage of training; creating a second training set based on the modified first training set and at least some of the plurality of aligned parallel sentences not in the first training set; and training the natural language translation model in a second stage using the second training set so as to improve translation performance of the natural language translation model.

Abstract: A third party system includes a tracking mechanism in various content provided by the third party system. When a client device presents content provided by the third party system, the client device executes tracking mechanism, causing the client device to communicate information identifying the content, identifying a user associated with the online system, and other information to the online system. Based on the information received from the client device, the online system selects a rule from rules provided to the online system by the third party system. The online system then performs an action included in the selected rule, allowing the advertiser to initiate various actions by the online system while including a common tracking mechanism in different content provided by the third party system.

Abstract: The disclosure provides a torque release tubing rotator comprising a rotator body and a split drive mandrel rotatably coupled to the rotator body. The split drive mandrel receives and engages at least a portion of a tubing hanger. The split drive mandrel comprises an outer driven portion, an inner mandrel portion, and a one-way locking mechanism coupling the outer driven portion and the inner mandrel portion. The disclosure also provides a torque release tubing hanger for a tubing rotator comprising an outer housing, a tubing mandrel suspended from the outer housing, and a locking swivel rotatably coupled to the outer housing. The locking swivel is movable between a locked configuration and an unlocked configuration. A bi-directional coupling is also provided. The disclosure also provides a torque release tubing rotator system comprising the tubing rotator and tubing hanger.

Abstract: A third party system includes a tracking mechanism in various content provided by the third party system. When a client device presents content provided by the third party system, the client device executes tracking mechanism, causing the client device to communicate information identifying the content, identifying a user associated with the online system, and other information to the online system. Based on the information received from the client device, the online system selects a rule from rules provided to the online system by the third party system. The online system then performs an action included in the selected rule, allowing the advertiser to initiate various actions by the online system while including a common tracking mechanism in different content provided by the third party system.

Abstract: A third party system includes a tracking mechanism in various content provided by the third party system. When a client device presents content provided by the third party system, the client device executes tracking mechanism, causing the client device to communicate information identifying the content, identifying a user associated with the online system, and other information to the online system. Based on the information received from the client device, the online system selects a rule from rules provided to the online system by the third party system. The online system then performs an action included in the selected rule, allowing the advertiser to initiate various actions by the online system while including a common tracking mechanism in different content provided by the third party system.

Abstract: The disclosure provides a torque release tubing rotator comprising a rotator body and a split drive mandrel rotatably coupled to the rotator body. The split drive mandrel receives and engages at least a portion of a tubing hanger. The split drive mandrel comprises an outer driven portion, an inner mandrel portion, and a one-way locking mechanism coupling the outer driven portion and the inner mandrel portion. The disclosure also provides a torque release tubing hanger for a tubing rotator comprising an outer housing, a tubing mandrel suspended from the outer housing, and a locking swivel rotatably coupled to the outer housing. The locking swivel is movable between a locked configuration and an unlocked configuration. A bi-directional coupling is also provided. The disclosure also provides a torque release tubing rotator system comprising the tubing rotator and tubing hanger.

Abstract: Annexin A3 (ANAX3) is utilized as a biomarker for the diagnosis and prognosis of hepatocellular carcinoma (HCC) and the utilization of a monoclonal antibody against ANXA3 or antisense polynucleotide against ANXA3 mRNA for the suppression or treatment of HCC, alone or in combination with other HCC treatment. Monoclonal antibody against ANXA3 can be administered for the suppression of tumor growth, metastasis, and chemoresistance.

Abstract: A third party system includes a tracking mechanism in various content provided by the third party system. When a client device presents content provided by the third party system, the client device executes tracking mechanism, causing the client device to communicate information identifying the content, identifying a user associated with the online system, and other information to the online system. Based on the information received from the client device, the online system selects a rule from rules provided to the online system by the third party system. The online system then performs an action included in the selected rule, allowing the advertiser to initiate various actions by the online system while including a common tracking mechanism in different content provided by the third party system.

Abstract: Annexin A3 (ANAX3) is utilized as a biomarker for the diagnosis and prognosis of hepatocellular carcinoma (HCC) and the utilization of a monoclonal antibody against ANXA3 or antisense polynucleotide against ANXA3 mRNA for the suppression or treatment of HCC, alone or in combination with other HCC treatment. Monoclonal antibody against ANXA3 can be administered for the suppression of tumor growth, metastasis, and chemoresistance.

Abstract: Annexin A3 (ANAX3) is utilized as a biomarker for the diagnosis and prognosis of hepatocellular carcinoma (HCC) and the utilization of a monoclonal antibody against ANXA3 or antisense polynucleotide against ANXA3 mRNA for the suppression or treatment of HCC, alone or in combination with other HCC treatment. Monoclonal antibody against ANXA3 can be administered for the suppression of tumor growth, metastasis, and chemoresistance.

Abstract: Annexin A3 (ANAX3) is utilized as a biomarker for the diagnosis and prognosis of hepatocellular carcinoma (HCC) and the utilization of a monoclonal antibody against ANXA3 or antisense polynucleotide against ANXA3 mRNA for the suppression or treatment of HCC, alone or in combination with other HCC treatment. Monoclonal antibody against ANXA3 can be administered for the suppression of tumor growth, metastasis, and chemoresistance.