Abstract: The present disclosure relates to bi-specific antibodies that specifically bind and neutralize both tumor necrosis factor ? (TNF?) and interleukin-1? (IL-1?), and to the use of such bispecific antibodies for the therapeutic treatment of TNF? and IL-1?-mediated diseases and disorders.

Abstract: A pressure sensor die especially suitable for high-temperature, high-pressure operating environment and delivering accurate and reliable pressure measurement at low cost. A single crystalline silicon includes a cap, a substrate and a base connected together. A recess formed on the cap creates an upper sealed cavity with the substrate. A silicon oxide layer is formed between the substrate and the cap. A recess formed on the base creates a lower sealed cavity with the substrate. The upper sealed cavity and the lower sealed cavity overlap in their projections. The substrate includes at least two sets of piezoresistive sensing elements located within the overlapping projections, perpendicular to each other, and oriented in different crystallographic directions.

Abstract: Absorbent cores comprising a layered structure and methods of manufacture are disclosed. In one embodiment, an absorbent body may comprise a top layer comprising a liquid permeable web material, a bottom layer comprising a web material, and a reinforcement layer disposed between the top layer and the bottom layer. The absorbent body may further comprise a first absorbent layer disposed between the reinforcement layer and the bottom layer, the first absorbent layer comprising absorbent material which comprises substantially only superabsorbent material and a second absorbent layer disposed between the top layer and the reinforcement layer, the second absorbent layer comprising absorbent material which comprises absorbent material. The body may also comprise adhesive disposed between the top layer and the second absorbent layer, between the second absorbent layer and the reinforcement layer, and between the first absorbent layer and the bottom layer.

Abstract: Disclosed are immunogens including a recombinant RSV F protein stabilized in a prefusion conformation. Also disclosed are nucleic acids encoding the immunogens and methods of producing the immunogens. Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the immunogen to the subject.

Abstract: Systems and methods providing low-density parity-check (LDPC) decoder configurations capable of decoding multiple code blocks in parallel are described. Parallel LDPC decoders of embodiments can be reconfigured to simultaneously decode multiple codewords with reconfigurable size. In operation of embodiments of a parallel LDPC decoder, a plurality of active portions of the decoder logic are configured for parallel processing of a plurality of code blocks, wherein each active region processes a respective code block. The decoder logic active portions of embodiments are provided using a reconfigurable segmented scalable cyclic shifter supporting multiple instruction, multiple data (MIMD), wherein multiple individual different data shifts are implemented with respect to a plurality of code blocks in an instance of data shifting operation.

Abstract: A pressure sensor die especially suitable for high-temperature, high-pressure operating environment and delivering accurate and reliable pressure measurement at low cost. A single crystalline silicon includes a cap, a substrate and a base connected together. A recess formed on the cap creates an upper sealed cavity with the substrate. A silicon oxide layer is formed between the substrate and the cap. A recess formed on the base creates a lower sealed cavity with the substrate. The upper sealed cavity and the lower sealed cavity overlap in their projections. The substrate includes at least two sets of piezoresistive sensing elements located within the overlapping projections, perpendicular to each other, and oriented in different crystallographic directions.

Abstract: Described is a method of reducing uplink inter-cell interference in a cellular communications network. The method comprises identifying in a cell any user equipments (UEs) which are susceptible to interference (ISUs) from another UE, particularly another UE in a neighboring cell. The method includes identifying in said cell any UEs causing interference (ICUs) to at least one neighboring cell and, more particularly, causing interference to a UE in a neighboring cell. The identified ISUs and ICUs are combined into a priority list for frequency resource reservation or allocation in said cell. The method may include limiting the identification of ISUs and ICUs to a selected number of UEs within the cell.

Abstract: Automatic test equipment with multiple components to generate highly accurate and stable analog test signals and method for operating the test system in semiconductor manufacturing process are disclosed. Output analog signals from existing test systems often fail the stability and accuracy requirement with less than 10 mV variations for testing certain electronic devices, due in part to environmental condition variations such as temperature fluctuations. Traditional compensation mechanisms for temperature variations involve time consuming and disruptive calibration procedures. Disclosed here is a system and method that provides near real-time monitoring and compensation for temperature-induced variations via a digital control mechanism that compensates for environmental variations in a time scale of less than 10 milliseconds and maintains the AC output analog signal with 10 milliVolt accuracy.

Abstract: Systems and methods providing low-density parity-check (LDPC) decoder configurations capable of decoding multiple code blocks in parallel are described. Parallel LDPC decoders of embodiments can be reconfigured to simultaneously decode multiple codewords with reconfigurable size. In operation of embodiments of a parallel LDPC decoder, a plurality of active portions of the decoder logic are configured for parallel processing of a plurality of code blocks, wherein each active region processes a respective code block. The decoder logic active portions of embodiments are provided using a reconfigurable segmented scalable cyclic shifter supporting multiple instruction, multiple data (MIMD), wherein multiple individual different data shifts are implemented with respect to a plurality of code blocks in an instance of data shifting operation.

Abstract: Software that selects portions of unlabeled text for labeling, by performing the following operations: (i) receiving a set of unlabeled input text for classification with respect to a particular domain, wherein the domain includes a labeled corpus for which topics of a set of topics correspond to labels from the corpus, and wherein the topics include statistical probability distributions of words in the corpus; (ii) performing topic modeling on the input text to associate portions of the input text with respective classifications, wherein the classifications include statistical probability distributions of topics of the set of topics in the respective portions of the input text; and (iii) applying a machine learning-based selection strategy to the portions of the input text and their respective classifications to identify one or more portions of the input text for labeling.

Abstract: Provided is a method for determining a Hybrid Automatic Repeat Request (HARQ) transmission signal. The method comprises receiving soft bits from a wireless communication physical channel uplink signal, said received soft bits being deemed to comprise HARQ LLRs and soft decoding said HARQ LLRs to output a hard ACK/NACK decision. The method includes processing said HARQ LLRs based on said hard ACK/NACK decision such that the processed HARQ LLRs map to a same or identical constellation point or points if the physical channel uplink signal contains an ACK or NACK transmission signal. The method also includes using said processed HARQ LLRs to determine if the physical channel uplink signal contains an ACK or NACK transmission signal or to determine if the physical channel uplink signal comprises discontinuous transmission (DTX).

Abstract: A geogrid and a manufacturing method thereof. The geogrid comprises multiple ribs, and the multiple ribs are connected to each other at multiple junctions to form multiple cells. At each junction, two or more adjacent ribs of the multiple ribs are inserted into each other via inserts, and each junction is covered by a plastic material. The geogrid can easily be extended to a present state at a construction site, prevent tearing of apertures, prevent soil from leaking from the apertures, and prevent the inserts from rusting or corroding. Since the plastic material, the ribs, and the inserts are bonded to each other, separation strength at the junction is markedly increased. Preferably, an end portion of the insert is completely covered by the plastic material to form an end cap, and the plastic material and the ribs and the inserts are bonded to each other to form columns.

Abstract: The invention provides novel compositions and methods for the treatment of Radiation-Induced Bystander Effects (RIBE), resulting from radiation exposure. In one preferred embodiment the inventions includes novel therapeutic agents, including but not limited to quercetin and quercetin analogs, as well as E64, CA074, CA074Me, that interfere with the activity of Cathepsin B.

Abstract: Certain embodiments of the invention provide a lubricating oil composition comprising a lubricating oil base stock and a compound of formula (I): or a salt thereof, wherein R1, R2, R3 and R4 have any of the values defined in the specification, as well as methods of use thereof.

Abstract: An image sensing device includes a photoelectric device disposed within a semiconductor substrate, and a separation structure and electrode structures disposed within the semiconductor substrate, and surrounding the photoelectric device. The separation structure includes a first conductive pattern, and a first insulating spacer between the first conductive pattern and the semiconductor substrate. A respective one of the electrode structures includes a second conductive pattern, and a second insulating spacer between the second conductive pattern and the semiconductor substrate. The first conductive pattern and the second conductive pattern are formed of the same conductive material.

Abstract: Provided is a nucleic acid aptamer screening method based on the localized surface plasmon resonance technology, falling within the fields of molecular recognition and nucleic acid aptamer screening. The method screens out a nucleic acid aptamer that can specifically bind to a target mainly with the aid of a localized surface plasmon resonance personal molecular interaction analyzer. The screening method comprises: taking a nano-gold chip as a medium, fixing the target on the medium, and then carrying out the visualized screening of the nucleic acid aptamer by taking the nucleic acid aptamer as a recognition element. With the aid of the LSPR-SELEX technique, the method does not require any marker during the process of detection by using a solid chip, and maintains the spatial structure and biological activity of the nucleic acid aptamer at the maximum.

Abstract: Methods and systems for determining a ball shot attempt result, the ball shot attempt captured by a camera on a mobile computing device, are disclosed. The methods and systems perform steps comprising receiving an input video captured using the camera on the mobile computing device, wherein the input video comprises a ball shot attempt at a goal; receiving a declared ball shot attempt, the declared ball shot attempt detected by analyzing a ball trajectory in the input video; detecting an element movement associated with an element of the goal; and determining the ball shot attempt result based on the element movement and the ball trajectory. In some embodiments, the element of the goal is a net, and the declared ball shot attempt is detected by analyzing the ball trajectory in a ball shot attempt Region of Interest (ROI) within frames of the input video.

Abstract: The present invention discloses an organic electroluminescence device, comprising a luminescent layer, wherein, a host material of the luminescent layer comprises a thermally activated delayed fluorescence material, the host material is doped by a dye, and the dye comprises at least one phosphorescent dye. The present invention employs a thermally activated delayed fluorescence material, whose difference between the triplet state energy level and the singlet state energy level (?EST) is relatively small. The present invention employs the material as the phosphorescence host, so part of the triplet state exciton level transfers to the singlet state excitons, and the amount of the overall triplet state excitons is smaller.

Abstract: The present invention discloses a method for lowering an oil pipe in a gas well without well-killing, a soluble bridge plug and a material preparation method thereof, wherein, the method comprises the steps of: lowering a bridge plug in a wellbore such that the bridge plug blocks the wellbore at a predetermined location in the wellbore; injecting water in the wellbore after the pressure in the wellbore has been relieved so as to replace gases in the wellbore; and lowering an oil pipe in the wellbore to the location of the bridge plug. The method for lowering an oil pipe in a gas well without well-killing, the soluble bridge plug and the material preparation method thereof provided in the present invention successfully solve the problem of high cost for lowering an oil pipe under pressure after a fracturing fluid has been injected into the casing.

Abstract: A development tool is described herein. The development tool automatically identifies one or more resources associated with a first version of a Web site that is being developed by a user of the tool. The development tool also automatically interacts with at least one entity within a Web hosting environment to cause a companion resource to be provisioned in the Web hosting environment for each local resource so identified. The development tool may also automatically interact with at least one entity within the Web hosting environment to properly configure a published version of the Web site to utilize at least one companion resource.