Patents by Inventor Manabu Ato

Manabu Ato has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR PRODUCING INFLUENZA HA SPLIT VACCINE
    Publication number: 20230406910
    Abstract: Provided is a method for producing an influenza HA split vaccine which produces an antibody that binds to a HA stem region of influenza, the HA stem region being less likely to cause antigenic variation, An influenza HA split vaccine is subjected to an acidic treatment. Through the acidic treatment, an influenza HA split vaccine which produces an antibody that binds to a LAH of the HA stem region is obtained. This influenza HA split vaccine has an excellent protective ability against infection of other influenza viruses of different antigenicity.
    Type: Application
    Filed: June 27, 2023
    Publication date: December 21, 2023
    Inventors: Yoshimasa Takahashi, Yu Adachi, Manabu Ato
  • Method for producing influenza HA split vaccine
    Patent number: 11732031
    Abstract: Provided is a method for producing an influenza HA split vaccine which produces an antibody that binds to a HA stem region of influenza, the HA stem region being less likely to cause antigenic variation, An influenza HA split vaccine is subjected to an acidic treatment. Through the acidic treatment, an influenza HA split vaccine which produces an antibody that binds to a LAH of the HA stem region is obtained. This influenza HA split vaccine has an excellent protective ability against infection of other influenza viruses of different antigenicity.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: August 22, 2023
    Assignee: JAPAN as represented by DIRECTOR GENERAL of National Institute of Infectious Diseases
    Inventors: Yoshimasa Takahashi, Yu Adachi, Manabu Ato
  • METHOD FOR PREPARING INFLUENZA HA SPLIT VACCINE
    Publication number: 20220152191
    Abstract: Provided is a method for producing an influenza HA split vaccine which produces an antibody that binds to an HA stem region of influenza, the HA stem region being less likely to cause antigenic variation, An influenza HA split vaccine is subjected to an acidic treatment. Through the acidic treatment, an influenza HA split vaccine which produces an antibody that binds to an LAH of the HA stem region is obtained. This influenza HA split vaccine has an excellent ability against infection of other influenza viruses of different antigenicity.
    Type: Application
    Filed: March 3, 2020
    Publication date: May 19, 2022
    Inventors: Yoshimasa Takahashi, Yu Adachi, Manabu Ato
  • COMPOSITION CONTAINING INFLUENZA VACCINE
    Publication number: 20210353737
    Abstract: The present invention provides a composition comprising a universal influenza vaccine antigen and a vaccine adjuvant.
    Type: Application
    Filed: July 22, 2019
    Publication date: November 18, 2021
    Inventors: Yoshimasa Takahashi, Yu Adachi, Manabu Ato, Akihisa Fukushima
  • Method for producing influenza HA split vaccine
    Publication number: 20190345231
    Abstract: Provided is a method for producing an influenza HA split vaccine which produces an antibody that binds to a HA stem region of influenza, the HA stem region being less likely to cause antigenic variation, An influenza HA split vaccine is subjected to an acidic treatment. Through the acidic treatment, an influenza HA split vaccine which produces an antibody that binds to a LAH of the HA stem region is obtained. This influenza HA split vaccine has an excellent protective ability against infection of other influenza viruses of different antigenicity.
    Type: Application
    Filed: March 4, 2019
    Publication date: November 14, 2019
    Inventors: Yoshimasa Takahashi, Yu Adachi, Manabu Ato
  • Modified H7 Hemagglutinin Glycoprotein of the Influenza A/Shanghai/2/2013 H7 Sequence
    Publication number: 20180179256
    Abstract: The present invention is directed to a sequence modification of the H7 hemagglutinin glycoprotein of the Influenza A/Shanghai/2/2013 H7 sequence together with vaccines derived therefrom. In addition, the invention further comprises method for improving the efficacy of vaccine antigens by modifying T cell epitopes.
    Type: Application
    Filed: April 15, 2016
    Publication date: June 28, 2018
    Applicants: EpiVax, Inc., National Institute of Infectious Diseases
    Inventors: Anne S De Groot, William D Martin, Yoshimasa Takahashi, Manabu Ato