Patents by Inventor Manabu Kawada

Manabu Kawada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compound, production method therefor, and use of said compound
    Patent number: 10202347
    Abstract: The present application provides novel compounds having anti-cancer or anti-Helicobacter pylori activity, pharmaceutical compositions and method for producing and using the novel compound.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: February 12, 2019
    Assignee: MICROBIAL CHEMISTRY RESEARCH FOUNDATION
    Inventors: Manabu Kawada, Hikaru Abe, Takumi Watanabe, Hiroyuki Inoue, Shun-ichi Ohba, Chigusa Hayashi, Masayuki Igarashi
  • Compound, production method therefor, and use of said compound
    Patent number: 10160725
    Abstract: The present application provides novel compounds having anti-cancer or anti-Helicobacter pylori activity, pharmaceutical compositions and method for producing and using the novel compound.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: December 25, 2018
    Assignee: MICROBIAL CHEMISTRY RESEARCH FOUNDATION
    Inventors: Manabu Kawada, Hikaru Abe, Takumi Watanabe, Hiroyuki Inoue, Shun-ichi Ohba, Chigusa Hayashi, Masayuki Igarashi
  • NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND USE OF SAID COMPOUND
    Publication number: 20180093954
    Abstract: The present application provides novel compounds having anti-cancer or anti-Helicobacter pylori activity, pharmaceutical compositions and method for producing and using the novel compound.
    Type: Application
    Filed: November 17, 2017
    Publication date: April 5, 2018
    Inventors: Manabu KAWADA, Hikaru ABE, Takumi WATANABE, Hiroyuki INOUE, Shun-ichi OHBA, Chigusa HAYASHI, Masayuki IGARASHI
  • Compound, production method therefor, and use of said compound
    Patent number: 9850211
    Abstract: A compound expressed by any one of Structural Formulas (1) to (13), a method for producing the same, and a compound-containing composition, an anti-cancer agent, and an anti-Helicobacter pylori agent each containing the above compound.
    Type: Grant
    Filed: March 1, 2017
    Date of Patent: December 26, 2017
    Assignee: MICROBIAL CHEMISTRY RESEARCH FOUNDATION
    Inventors: Manabu Kawada, Hikaru Abe, Takumi Watanabe, Hiroyuki Inoue, Shun-ichi Ohba, Chigusa Hayashi, Masayuki Igarashi
  • NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND USE OF SAID COMPOUND
    Publication number: 20170174631
    Abstract: A compound expressed by any one of Structural Formulas (1) to (13), a method for producing the same, and a compound-containing composition, an anti-cancer agent, and an anti-Helicobacter pylori agent each containing the above compound.
    Type: Application
    Filed: March 1, 2017
    Publication date: June 22, 2017
    Inventors: Manabu KAWADA, Hikaru ABE, Takumi WATANABE, Hiroyuki INOUE, Shun-ichi OHBA, Chigusa HAYASHI, Masayuki IGARASHI
  • Compound, production method therefor, and use of said compound
    Patent number: 9617217
    Abstract: The present application provides novel compounds having anti-cancer or anti-Helicobacter pylori activity, pharmaceutical compositions and method for producing and using the novel compound.
    Type: Grant
    Filed: February 24, 2014
    Date of Patent: April 11, 2017
    Assignee: MICROBIAL CHEMISTRY RESEARCH FOUNDATION
    Inventors: Manabu Kawada, Hikaru Abe, Takumi Watanabe, Hiroyuki Inoue, Shun-ichi Ohba, Chigusa Hayashi, Masayuki Igarashi
  • Anti-CXADR antibody
    Patent number: 9416189
    Abstract: An object is to find a target molecule effective for cancer treatments and the like and to provide an antibody capable of specifically binding to the molecule, an anticancer agent comprising the antibody as an active ingredient, and so forth. Hence, prostate cancer cell lines (LNCaP-CR cells and LNCaP cells) were compared by SST-REX, and CXADR was identified as a molecule involved in tumor formation and so on. Then, a monoclonal antibody against CXADR was prepared, and the anti-cancer activity, ADCC activity, CDC activity, and so forth were examined. The result revealed that an antibody capable of binding to an epitope present at positions 181 to 230 of a CXADR protein derived from human exhibited an anti-cancer activity against prostate cancer cells, pancreatic cancer cells, and colorectal cancer cells. Further, it was also revealed that the antibody had an ADCC activity and a CDC activity. Moreover, the structures of light chain and heavy chain variable regions of the antibody were successfully determined.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: August 16, 2016
    Assignees: MICROBIAL CHEMISTRY RESEARCH FOUNDATION, MEDICAL & BIOLOGICAL LABORATORIES CO., LTD.
    Inventors: Manabu Kawada, Hiroyuki Inoue, Shuichi Sakamoto, Masunori Kajikawa, Masahito Sugiura, Sakiko Urano
  • NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND USE OF SAID COMPOUND
    Publication number: 20160009651
    Abstract: The present application provides novel compounds having anti-cancer or anti-Helicobacter pylori activity, pharmaceutical compositions and method for producing and using the novel compound.
    Type: Application
    Filed: February 24, 2014
    Publication date: January 14, 2016
    Inventors: Manabu KAWADA, Hikaru ABE, Takumi WATANABE, Hiroyuki INOUE, Shun-ichi OHBA, Chigusa HAYASHI, Masayuki IGARASHI
  • ANTI-CXADR ANTIBODY
    Publication number: 20150140018
    Abstract: An object is to find a target molecule effective for cancer treatments and the like and to provide an antibody capable of specifically binding to the molecule, an anticancer agent comprising the antibody as an active ingredient, and so forth. Hence, prostate cancer cell lines (LNCaP-CR cells and LNCaP cells) were compared by SST-REX, and CXADR was identified as a molecule involved in tumor formation and so on. Then, a monoclonal antibody against CXADR was prepared, and the anti-cancer activity, ADCC activity, CDC activity, and so forth were examined. The result revealed that an antibody capable of binding to an epitope present at positions 181 to 230 of a CXADR protein derived from human exhibited an anti-cancer activity against prostate cancer cells, pancreatic cancer cells, and colorectal cancer cells. Further, it was also revealed that the antibody had an ADCC activity and a CDC activity. Moreover, the structures of light chain and heavy chain variable regions of the antibody were successfully determined.
    Type: Application
    Filed: May 13, 2013
    Publication date: May 21, 2015
    Applicants: MEDICAL & BIOLOGICAL LABORATORIES CO., LTD., MICROBIAL CHEMISTRY RESEARCH FOUNDATION
    Inventors: Manabu Kawada, Hiroyuki Inoue, Shuichi Sakamoto, Masunori Kajikawa, Masahito Sugiura, Sakiko Urano
  • Compound ceramidastin, method for producing the same, and use of the same
    Patent number: 8263369
    Abstract: A compound having a structure expressed by the following Structural Formula (1):
    Type: Grant
    Filed: March 1, 2011
    Date of Patent: September 11, 2012
    Assignee: Microbial Chemistry Research Foundation
    Inventors: Hiroyuki Inoue, Manabu Kawada, Daishiro Ikeda
  • NOVEL COMPOUND CERAMIDASTIN, METHOD FOR PRODUCING THE SAME, AND USE OF THE SAME
    Publication number: 20110213164
    Abstract: A compound having a structure expressed by the following Structural Formula (1):
    Type: Application
    Filed: March 1, 2011
    Publication date: September 1, 2011
    Applicant: MICROBIAL CHEMISTRY RESEARCH FOUNDATION
    Inventors: Hiroyuki Inoue, Manabu Kawada, Daishiro Ikeda
  • Method of visualizing music system by combination of scenery picture and player icons
    Patent number: 6140565
    Abstract: A method is designed for displaying a visual image of a music system that is constructed to play at least one performance part with a particular timbre and that is applied with an acoustic effect, an accompaniment style and the like.
    Type: Grant
    Filed: June 7, 1999
    Date of Patent: October 31, 2000
    Assignee: Yamaha Corporation
    Inventors: Akira Yamauchi, Manabu Kawada, Yasuhiko Okamura, Yasushi Kurakake, Kenichiro Saito, Yoshiko Fukushima
  • Electronic keyboard instrument
    Patent number: D552157
    Type: Grant
    Filed: June 3, 2005
    Date of Patent: October 2, 2007
    Assignee: Yamaha Corporation
    Inventors: Manabu Kawada, Tamie Onishi, Enrico Bergese
  • Electronic keyboard instrument
    Patent number: D554178
    Type: Grant
    Filed: June 3, 2005
    Date of Patent: October 30, 2007
    Assignee: Yamaha Corporation
    Inventors: Manabu Kawada, Tamie Onishi, Enrico Bergese
  • Electronic percussion
    Patent number: D569896
    Type: Grant
    Filed: April 4, 2007
    Date of Patent: May 27, 2008
    Assignee: Yamaha Corporation
    Inventors: Enrico Bergese, Manabu Kawada, Akie Hinokio
  • Electronic keyboard instrument
    Patent number: D599841
    Type: Grant
    Filed: October 6, 2008
    Date of Patent: September 8, 2009
    Assignee: Yamaha Corporation
    Inventor: Manabu Kawada
  • Electronic percussion
    Patent number: D614686
    Type: Grant
    Filed: April 4, 2007
    Date of Patent: April 27, 2010
    Assignee: Yamaha Corporation
    Inventors: Enrico Bergese, Manabu Kawada, Akie Hinokio
  • Electronic keyboard musical instrument
    Patent number: D382005
    Type: Grant
    Filed: January 16, 1996
    Date of Patent: August 5, 1997
    Assignee: Yamaha Corporation
    Inventor: Manabu Kawada
  • Electronic percussion instrument
    Patent number: D387374
    Type: Grant
    Filed: June 25, 1996
    Date of Patent: December 9, 1997
    Assignee: Yamaha Corporation
    Inventor: Manabu Kawada
  • Disc player with radio tuner
    Patent number: D405790
    Type: Grant
    Filed: May 14, 1998
    Date of Patent: February 16, 1999
    Assignee: Yamaha Corporation
    Inventors: Manabu Kawada, Yoshihiro Katsumata