Patents by Inventor Manabu Murakami

Manabu Murakami has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050170926
    Abstract: In a continuously variable transmission metal belt, a lateral-most projecting portion of a side edge of a metal ring assembly wherein each metal ring is located between a radially central plane and a radially inner peripheral surface of the metal ring. A contact point in which the projecting portion abuts against a V-face of a pulley is closer to the radially central plane than to the radially inner peripheral surface. Moreover, as the metal rings are laminated on one another, recesses are formed between the side edges of the adjacent metal rings to retain oil therein, which lubricates the sliding faces of adjacent metal rings and enhances durability of the assembly.
    Type: Application
    Filed: December 23, 2004
    Publication date: August 4, 2005
    Inventors: Hideaki Aoyama, Toru Yagasaki, Manabu Murakami, Shigeru Kanehara
  • Patent number: 6841549
    Abstract: The present invention provides a preventive or therapeutic agent for diabetes mellitus and diabetic complications, which is a new type based on an adenosine A2 receptor antagonist action. That is, it provides a novel condensed imidazole compound which has an adenosine A2 receptor antagonist action, is effective for preventing or treating diabetes mellitus and diabetic complications, and is represented by the formula (I); (wherein R1 represents e.g. an amino group which may be substituted with an alkyl group; R2 represents e.g. hydrogen atom, an alkyl group, a cycloalkyl group or an alkyl group, alkenyl group or alkynyl group which may be substituted with hydrox etc.; R3 represents e.g. an optionally substituted alkyl group, alkenyl group, alkynyl group, aryl group, heteroaryl group, pyridinone group, pyrimidinone group or piperadinone group; Ar represents e.g.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: January 11, 2005
    Assignee: Eisai Co., Ltd.
    Inventors: Osamu Asano, Hitoshi Harada, Seiji Yoshikawa, Nobuhisa Watanabe, Takashi Inoue, Tatsuo Horizoe, Nobuyuki Yasuda, Kaya Ohashi, Hiroe Minami, Junsaku Nagaoka, Manabu Murakami, Seiichi Kobayashi, Isao Tanaka, Tsutomu Kawata, Naoyuki Shimomura, Hiroshi Akamatsu, Naoki Ozeki, Toshikazu Shimizu, Kenji Hayashi, Toyokazu Haga, Shigeto Negi, Toshihiko Naito
  • Patent number: 6744012
    Abstract: A control method for arc welding wherein position control of an electrode or a torch is performed while adjusting welding conditions on the basis of optical information obtained from arc light generated during an arc welding process. Illuminance, which forms the optical information obtained from the arc light, has a certain mutual relationship with the arc length or the torch height, so that the weld control is accomplished based on the illuminance. The control method includes a step of comparing illuminance with reference information based on the mutual relationship, and a step of adjusting the welding conditions on the basis of a result of comparison.
    Type: Grant
    Filed: June 27, 2002
    Date of Patent: June 1, 2004
    Assignee: Honda Giken Kogyo Kabushiki Kaisha
    Inventors: Koji Ueda, Manabu Murakami, Akira Yanagita, Takeshi Yamagami, Katsuya Kugai, Yusuke Niimura, Akinobu Izawa, Rintaro Chinen
  • Publication number: 20030203853
    Abstract: A composition for prophylaxis and therapy of dermal aging which comprises a substance having human leukocyte elastase inhibitory activity as an active ingredient.
    Type: Application
    Filed: April 3, 2003
    Publication date: October 30, 2003
    Applicant: Fujisawa Pharmaceutical Co. Ltd.
    Inventors: Tsuguo Yabuta, Mitsuru Yasumura, Kunio Nakahara, Yusuke Furukawa, Kazuhiko Nomura, Manabu Murakami
  • Patent number: 6610748
    Abstract: A composition for prophylaxis and therapy of dermal aging which comprises a substance having human leukocyte elastase inhibitory activity as an active ingredient.
    Type: Grant
    Filed: December 15, 2000
    Date of Patent: August 26, 2003
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Tsuguo Yabuta, Mitsuru Yasumura, Kunio Nakahara, Yusuke Furukawa, Kazuhiko Nomura, Manabu Murakami
  • Patent number: 6579868
    Abstract: The present invention provides a preventive or therapeutic agent of a new type for diabetes mellitus and diabetic complications on the basis of an adenosine A2 receptor antagonistic action. A purine compound represented by the formula (I), its pharmacologically acceptable salt or hydrates thereof has an adenosine A2 receptor antagonistic action and is useful for prevention or therapy of diabetes mellitus and diabetic complications. In addition, adenosine A2 receptor antagonists having different structures from those of the compounds described above, for example KW6002, are also effective for prevention or therapy of diabetes mellitus and diabetic complications. In the formula, W is —CH2CH2—, —CH═CH— or —C≡C—; R1 is: (in the formula, X is hydrogen atom, hydroxyl group, a lower alkyl group, a lower alkoxy group, etc.
    Type: Grant
    Filed: July 5, 2000
    Date of Patent: June 17, 2003
    Assignee: Eisai Co., Ltd.
    Inventors: Osamu Asano, Hitoshi Harada, Yorihisa Hoshino, Seiji Yoshikawa, Takashi Inoue, Tatsuo Horizoe, Nobuyuki Yasuda, Kaya Nagata, Junsaku Nagaoka, Manabu Murakami, Seiichi Kobayashi
  • Publication number: 20030000931
    Abstract: A control method for arc welding wherein position control of an electrode or a torch is performed while adjusting welding conditions on the basis of optical information obtained from arc light generated during an arc welding process. Illuminance, which forms the optical information obtained from the arc light, has a certain mutual relationship with the arc length or the torch height, so that the weld control is accomplished based on the illuminance. The control method includes a step of comparing illuminance with reference information based on the mutual relationship, and a step of adjusting the welding conditions on the basis of a result of comparison.
    Type: Application
    Filed: June 27, 2002
    Publication date: January 2, 2003
    Inventors: Koji Ueda, Manabu Murakami, Akira Yanagita, Takeshi Yamagami, Katsuya Kugai, Yusuke Niimura, Akinobu Izawa, Rintaro Chinen
  • Patent number: 5998445
    Abstract: Pyridine derivatives useful for preventing or treating peptic ulcers, pharmaceutical preparations and methods of treating peptic ulcers are described.
    Type: Grant
    Filed: July 9, 1996
    Date of Patent: December 7, 1999
    Assignee: Eisai Co., Ltd.
    Inventors: Shigeru Souda, Norihiro Ueda, Shuhei Miyazawa, Katsuya Tagami, Seiichiro Nomoto, Makoto Okita, Naoyuki Shimomura, Toshihiko Kaneko, Masatoshi Fujimoto, Manabu Murakami, Kiyoshi Oketani, Hideaki Fujisaki, Hisashi Shibata, Tsuneo Wakabayashi
  • Patent number: 5840910
    Abstract: Pyridine derivatives useful for preventing or treating peptic ulcers, pharmaceutical preparations and methods of treating peptic ulcers are disclosed.
    Type: Grant
    Filed: December 6, 1994
    Date of Patent: November 24, 1998
    Assignee: Esai Co., Ltd.
    Inventors: Shigeru Souda, Norihiro Ueda, Shuhei Miyazawa, Katsuya Tagami, Seiichiro Nomoto, Makoto Okita, Naoyuki Shimomura, Toshihiko Kaneko, Masatoshi Fujimoto, Manabu Murakami, Kiyoshi Oketani, Hideaki Fujisaki, Hisashi Shibata, Tsuneo Wakabayashi
  • Patent number: 5708013
    Abstract: A pyridine compound having the formula is disclosed and useful to treat the peptic ulcer. ##STR1## wherein R.sup.1 and R.sup.2 which may be the same or different are each a hydrogen atom, a lower alkyl group, a lower alkoxy group, a halogenated lower alkyl group, or a halogen atom, R.sup.3 and R.sup.4 which may be the same or different are each a hydrogen atom or a lower alkyl group, X is a group represented by the formula --S--, a group represented by the formula ##STR2## or a group represented by the formula ##STR3## and n is an integer of 1 to 6, provided that R.sup.3 and R.sup.4 are not simultaneously hydrogen atoms when n is 1.
    Type: Grant
    Filed: August 21, 1995
    Date of Patent: January 13, 1998
    Assignee: Eisai Co., Ltd.
    Inventors: Shigeru Souda, Norihiro Ueda, Shuhei Miyazawa, Katsuya Tagami, Seiichiro Nomoto, Makoto Okita, Naoyuki Shimomura, Toshihiko Kaneko, Masatoshi Fujimoto, Manabu Murakami, Kiyoshi Oketani, Hideaki Fujisaki, Hisashi Shibata, Tsuneo Wakabayashi
  • Patent number: 5635519
    Abstract: A benzothiazole derivative or a pharmacologically acceptable salt thereof of the following formula, as defined in the claims, which is useful as a preventive or therapeutic agent for diseases on which functions of suppressing leukotrienes and thromboxanes production are effective: ##STR1##
    Type: Grant
    Filed: February 15, 1995
    Date of Patent: June 3, 1997
    Assignee: Eisai Co., Ltd.
    Inventors: Yasushi Okamoto, Katsuya Tagami, Shigeki Hibi, Hirotoshi Numata, Naoki Kobayashi, Masanobu Shinoda, Tetsuya Kawahara, Manabu Murakami, Kiyoshi Oketani, Takashi Inoue, Takashi Yamanaka, Isao Yamatsu
  • Patent number: 5420144
    Abstract: A benzothiazole derivative or a pharmacologically acceptable salt thereof which is useful as a preventive or therapeutic agent for diseases on which functions of suppressing leukotrienes and thromboxanes production are effective.
    Type: Grant
    Filed: November 5, 1993
    Date of Patent: May 30, 1995
    Assignee: Eisai Co., Ltd.
    Inventors: Yasushi Okamoto, Katsuya Tagami, Shigeki Hibi, Hirotoshi Numata, Naoki Kobayashi, Masanobu Shinoda, Tetsuya Kawahara, Manabu Murakami, Kiyoshi Oketani, Takashi Inoue, Takashi Yamanaka, Isao Yamatsu
  • Patent number: 5300518
    Abstract: A benzothiazole derivative or a pharmacologically acceptable salt thereof which is useful as a preventive or therapeutic agent for diseases on which functions of suppressing leukotrienes and thromboxanes production are effective.A benzothiazole derivative represented by the following general formula (I): ##STR1## wherein R.sup.1 and R.sup.3 are either the same or different and represents a hydrogen atom, a lower alkyl group or a lower alkoxy group; R.sup.4 represents a group represented by the formula --(CH.sub.x)--.sub.q wherein q is a integer of from 1 to 4;R.sup.2 represents a hydrogen atom and;R.sup.5 and R.sup.6 are the same or different and each represent a hydrogen atom or a lower alkyl group; or a pharmacologically acceptable salt thereof.
    Type: Grant
    Filed: March 31, 1992
    Date of Patent: April 5, 1994
    Assignee: Eisai Co., Ltd.
    Inventors: Yasushi Okamoto, Katsuya Tagami, Shigeki Hibi, Hirotoshi Numata, Naoki Kobayashi, Masanobu Shinoda, Tetsuya Kawahara, Manabu Murakami, Kiyoshi Oketani, Takashi Inoue, Takashi Yamanaka, Isao Yamatsu
  • Patent number: 5239079
    Abstract: A pyridinium salt is useful as an antiulcer and is defined by the following formula. It includes a sulphenamide compound and a pyridinium compound. J is benzoimidazole, K is --S-- or --SSR, Z is hydroxy or oxyalkyl.
    Type: Grant
    Filed: August 13, 1992
    Date of Patent: August 24, 1993
    Assignee: Eisai Co., Ltd.
    Inventors: Shigeru Souda, Shuhei Miyazawa, Norihiro Ueda, Katsuya Tagami, Seiichiro Nomoto, Makoto Okita, Naoyuki Shimomura, Toshihiko Kaneko, Masatoshi Fujimoto, Manabu Murakami, Kiyoshi Oketani, Hideaki Fujisaki, Hisashi Shibata, Tsuneo Wakabayashi
  • Patent number: 5162317
    Abstract: A pyridinium salt useful as an antiulcer agent, defined by formula (I) is disclosed. It includes a sulphenamide compound and a pyridinium compound. J is benzimidazole, K is --S-- or --SSR-- and Z is hydroxy or alkoxy.
    Type: Grant
    Filed: December 5, 1989
    Date of Patent: November 10, 1992
    Assignee: Esai Co., Ltd.
    Inventors: Shigeru Souda, Shuhei Miyazawa, Norihiro Ueda, Katsuya Tagami, Seiichiro Nomoto, Makoto Okita, Naoyuki Shimomura, Toshihiko Kaneko, Masatoshi Fujimoto, Manabu Murakami, Kiyoshi Oketani, Hideaki Fujisaki, Hisashi Shibata, Tsuneo Wakabayashi
  • Patent number: 5045552
    Abstract: Pyridine derivatives useful for preventing or treating peptic ulcers, pharmaceutical preparations and methods of treating peptic ulcers are described.
    Type: Grant
    Filed: December 28, 1989
    Date of Patent: September 3, 1991
    Assignee: Eisai Co., Ltd.
    Inventors: Shigeru Souda, Norihiro Ueda, Shuhei Miyazawa, Katsuya Tagami, Seiichiro Nomoto, Makoto Okita, Naoyuki Shimomura, Toshihiko Kaneko, Masatoshi Fujimoto, Manabu Murakami, Kiyoshi Oketani, Hideaki Fujisaki, Hisashi Shibata, Tsuneo Wakabayashi
  • Patent number: 4989444
    Abstract: An industrial robot, designed for use in a press brake system, has a holding member for holding a plate shaped material, a base arm, and a working arm. The holding member nearly follows the plate shaped material without holding during a pressing process of the press brake by ensuring sufficient reciprocating distance between the holding member and the base arm, and by decreasing the mass of rotary axes and corresponding second arm members of the working arm which is used to control direction, altitude and other aspects of the plate shaped material. The industrial robot preferably ensures a degree of freedom in the width direction of the press brake by rotatably securing a first arm member to the base arm.
    Type: Grant
    Filed: August 8, 1989
    Date of Patent: February 5, 1991
    Assignee: Daikin Industries, Ltd.
    Inventors: Manabu Murakami, Masanori Yamashita, Tadafumi Mikoshi, Akihiko Fujii
  • Patent number: 4888439
    Abstract: A novel polyprenyl compound is identified with the formula and useful for a pharmaceutical drag. ##STR1## wherein X represents a group of the formula: ##STR2## (wherein R.sup.1 and R.sup.2, which may be the same or different, represent each a hydrogen atom, a lower alkyl group, a hydroxyalkyl group, or a lower alkenyl group); a group of the formula: ##STR3## (wherein A including the nitrogen atom shown represents a ring containing nitrogen and oxygen atoms); or a group of the formula: ##STR4## (wherein R.sup.3 represents a hydrogen atom or a lower alkyl group, and R.sup.4 represents a lower alkyl group); Y represents a group of the formula: ##STR5## or a group of the formula: ##STR6## (wherein R.sup.5 represents a hydrogen atom or a lower alkyl group), and n represents an integer of from 2 to 5.
    Type: Grant
    Filed: May 1, 1985
    Date of Patent: December 19, 1989
    Assignee: Eisai Co., Ltd.
    Inventors: Isao Yamatsu, Takeshi Suzuki, Shinya Abe, Kouji Nakamoto, Akiharu Kajiwara, Manabu Murakami, Kiyoshi Oketani, Hideaki Fujisaki
  • Patent number: 4791105
    Abstract: Dolichol or phosphate thereof is useful as a therapeutically treating and preventive agent, in particular, for hyperuricuria, hyperlipemia, diabetes and hepatic diseases.
    Type: Grant
    Filed: December 21, 1984
    Date of Patent: December 13, 1988
    Assignee: Eisai Co., Ltd.
    Inventors: Isao Yamatsa, Takeshi Suzuki, Shinya Abe, Kouji Nakamoto, Akiharu Kajiwara, Kouichi Katayama, Hajime Tsunoda, Manabu Murakami, Hideki Ono, Kouji Yamada
  • Patent number: 4782151
    Abstract: A novel polyprenyl compound is identified with the formula and useful for a pharmaceutical drag. ##STR1## wherein X represents a group of the formula: ##STR2## (wherein R.sup.1 and R.sup.2, which may be the same or differnt, represent each a hydrogen atom, a lower alkyl group, a hydroxyalkyl group, or a lower alkenyl group); a group of the formula: ##STR3## (wherein A including the nitrogen atom shown represents a ring containing nitrogen and oxygen atoms); or a group of the formula: ##STR4## (wherein R.sup.3 represents a hydrogen atom or a lower alkyl group, and R.sup.4 represents a lower alkyl group); Y represents a group of the formula: ##STR5## or a group of the formula: ##STR6## (wherein R.sup.5 represents a hydrogen atom or a lower alkyl group), and n represents an integer of from 2 to 5.
    Type: Grant
    Filed: January 29, 1988
    Date of Patent: November 1, 1988
    Assignee: Eisai Co., Ltd.
    Inventors: Isao Yamatsu, Takeshi Suzuki, Shinya Abe, Kouji Nakamoto, Akiharu Kajiwara, Manabu Murakami, Kiyoshi Oketani, Hideaki Fujisaki