Patents by Inventor Manabu Muto

Manabu Muto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10969390
    Abstract: A method for evaluating an efficacy of a chemoradiotherapy against squamous cell carcinoma comprises the following steps (a) to (c): (a) detecting an expression level of at least one gene selected from a SIM2 gene and genes co-expressed with the SIM2 gene in a squamous cell carcinoma specimen isolated from a subject; (b) comparing the expression level detected in the step (a) with a reference expression level of the corresponding gene; and (c) determining that an efficacy of a chemoradiotherapy against squamous cell carcinoma in the subject is high if the expression level in the subject is higher than the reference expression level as a result of the comparison in the step (b).
    Type: Grant
    Filed: September 24, 2015
    Date of Patent: April 6, 2021
    Assignees: NATIONAL CANCER CENTER, KYOTO UNIVERSITY, OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Hiroki Sasaki, Kazuhiko Aoyagi, Manabu Muto, Hiroo Takahashi
  • Publication number: 20170292955
    Abstract: A method for evaluating an efficacy of a chemoradiotherapy against squamous cell carcinoma comprises the following steps (a) to (c): (a) detecting an expression level of at least one gene selected from a SIM2 gene and genes co-expressed with the SIM2 gene in a squamous cell carcinoma specimen isolated from a subject; (b) comparing the expression level detected in the step (a) with a reference expression level of the corresponding gene; and (c) determining that an efficacy of a chemoradiotherapy against squamous cell carcinoma in the subject is high if the expression level in the subject is higher than the reference expression level as a result of the comparison in the step (b).
    Type: Application
    Filed: September 24, 2015
    Publication date: October 12, 2017
    Applicants: NATIONAL CANCER CENTER, KYOTO UNIVERSITY, OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Hiroki SASAKI, Kazuhiko AOYAGI, Manabu MUTO, Hiroo TAKAHASHI
  • Patent number: 5401109
    Abstract: A mounting bed integral with a hammer bank is disposed parallel to a counter balancer composed of a counter balancer constituting member and a yoke. The mounting bed and the yoke are provided with solenoid coils opposed to a permanent magnet provided on the frame, and a pair of bearings are arranged between the mounting bed and the counter balancer constituting member. A position sensor for the mounting bed and the counter balancer is provided. A controller is provided to control a current and direction of the solenoid coil by a detection signal from the position sensor. The mounting bed integral with the hammer bank and the counter balancer are shuttle-operated in opposite directions by the controller.
    Type: Grant
    Filed: February 24, 1994
    Date of Patent: March 28, 1995
    Assignees: Kabushiki Kaisha Yasakawa Denki, Ye Data, Inc.
    Inventors: Juichi Tatsumi, Manabu Muto, Kenji Mori, Hajime Hayase