Patents by Inventor Manabu Sasyou

Manabu Sasyou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrrolidine derivative and process for producing the same
    Publication number: 20040073045
    Abstract: A pyrrolidine derivative, which is an intermediate for a quinuclidine derivate side chain useful as a squalene synthase inhibitor, and producing method thereof are disclosed.
    Type: Application
    Filed: September 9, 2003
    Publication date: April 15, 2004
    Inventors: Manabu Sasyou, Toyokazu Haga, Akio Kayano, Shigeto Negi, Hiroyuki Naka
  • Process for producing stereoisomer of pyrrolidine derivative
    Patent number: 6620945
    Abstract: The present invention provides a process for producing optically active 3-hydroxy-4-methoxypyrrolidine, which is an intermediate for synthesizing a quinuclidine derivative useful as a squalene synthetase inhibitor, a salt thereof, or a hydrate thereof by subjecting a pyrrolidine derivative represented by the following formula (1-4): wherein R3a and R3b are different and each of R3a and R3b represents a hydrogen atom or a methyl group, to optical division purification by using an optically active dibenzoyltartaric acid derivative or the like.
    Type: Grant
    Filed: May 8, 2002
    Date of Patent: September 16, 2003
    Assignees: Eisai Co., Ltd., Yamakawa Chemical Industry Co., Ltd.
    Inventors: Toyokazu Haga, Akio Kayano, Manabu Sasyou, Shigeto Negi, Hiroyuki Naka, Hirofumi Noda, Ken-ichi Sakai
  • Process for producing stereoisomer of pyrrolidine derivative
    Publication number: 20030004208
    Abstract: The present invention provides a process for producing optically active 3-hydroxy-4-methoxypyrrolidine, which is an intermediate for synthesizing a quinuclidine derivative useful as a squalene synthetase inhibitor, a salt thereof, or a hydrate thereof by subjecting a pyrrolidine derivative represented by the following formula (1-4): 1
    Type: Application
    Filed: May 8, 2002
    Publication date: January 2, 2003
    Inventors: Toyokazu Haga, Akio Kayano, Manabu Sasyou, Shigeto Negi, Hiroyuki Naka, Hirofumi Noda, Ken-ichi Sakai