Patents by Inventor Manabu Sogabe
Manabu Sogabe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11382870Abstract: The present invention provides a risperidone-containing patch having an excellent drug release property and patch physical properties. Specifically, the present invention provides a medical patch comprising an adhesive composition comprising risperidone or a pharmaceutically acceptable salt thereof; a carboxylic acid; a fatty acid ester; and an adhesive, characterized in that said adhesive is a star-shaped acrylic block polymer having a star-shaped structure in which at least three chain polymer portions radiate from a sulfur residue of a mercapto group situated at the center, wherein the (meth)acrylic acid alkyl ester structural units having 7-17 carbon atoms account for 30-99.99% by mass of the whole structural units in said star-shaped acrylic block polymer, and at least one of said chain polymer portions has a structural unit having a copolymer structure of polymerizable monomers comprising a (meth)acrylic acid alkyl ester having 7-17 carbon atoms and a polyfunctional monomer.Type: GrantFiled: April 4, 2018Date of Patent: July 12, 2022Assignee: TEIKOKU SEIYAKU CO., LTD.Inventors: Satoshi Kawakami, Manabu Sogabe, Taiki Shibata, Hiroaki Hasegawa
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Patent number: 11179346Abstract: An external patch that contains rupatadine as a second-generation antihistamine, has excellent plaster physical properties, good adhesion to applied skin, and good transdermal absorption of rupatadine as an active ingredient is provided. The external patch containing rupatadine uses an acrylic adhesive as an adhesive base. Specifically, the external patch containing rupatadine uses an acrylic adhesive as an adhesive base and further contains an organic acid having 2 to 7 carbon atoms as a solubilizer, a fatty acid ester as a softener, and/or a surfactant.Type: GrantFiled: April 18, 2018Date of Patent: November 23, 2021Assignees: TEIKOKU SEIYAKU CO., LTD., J.URIACH Y COMPANIA S.A.Inventors: Satoshi Kawakami, Manabu Sogabe
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Patent number: 11077069Abstract: The present invention provides a star-shaped acrylic block polymer having a star-shaped structure in which at least three chain polymer portions radiate from a mercapto group situated at the center, wherein (meth)acrylic acid alkyl ester structural units having 7-17 carbon atoms account for 30-99.9% by mass of whole structural units of the star-shaped acrylic block polymer, and at least one of the chain polymer portions has a copolymer structure of polymerizable monomers containing a (meth)acrylic acid alkyl ester having 7-17 carbon atoms and a weakly basic monomer; and a medical patch containing an adhesive composition containing a salt of a basic drug and the star-shaped acrylic block polymer as an adhesive that exhibits high drug efficacy, that does not cause a decrease in adhesive property of an adhesive base due to an additive, and that causes less skin irritation.Type: GrantFiled: September 30, 2016Date of Patent: August 3, 2021Assignees: TEIKOKU SEIYAKU CO., LTD, NIPPON SHOKUBAI CO., LTD.Inventors: Satoshi Kawakami, Manabu Sogabe, Taiki Shibata, Yasushi Horikawa, Hiroaki Hasegawa
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Publication number: 20210085633Abstract: The purpose of the present invention is to provide a rivastigmine-containing transdermal absorption preparation having high adhesion to the skin and capable of continuously administering rivastigmine over a long period of time. A transdermal absorption preparation has rivastigmine, a rubber polymer, a tackifier resin, and a polymer compound having a nitrogen-containing group.Type: ApplicationFiled: July 12, 2018Publication date: March 25, 2021Applicant: TEIKOKU SEIYAKU CO., LTD.Inventors: Satoshi KAWAKAMI, Manabu SOGABE, Taiki SHIBATA
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Publication number: 20200121612Abstract: An external patch that contains rupatadine as a second-generation antihistamine, has excellent plaster physical properties, good adhesion to applied skin, and good transdermal absorption of rupatadine as an active ingredient is provided. The external patch containing rupatadine uses an acrylic adhesive as an adhesive base. Specifically, the external patch containing rupatadine uses an acrylic adhesive as an adhesive base and further contains an organic acid having 2 to 7 carbon atoms as a solubilizer, a fatty acid ester as a softener, and/or a surfactant.Type: ApplicationFiled: April 18, 2018Publication date: April 23, 2020Applicants: TEIKOKU SEIYAKU CO., LTD., J.URIACH Y COMPANIA S.A.Inventors: Satoshi KAWAKAMI, Manabu SOGABE
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Publication number: 20200108024Abstract: The present invention provides a risperidone-containing patch having an excellent drug release property and patch physical properties. Specifically, the present invention provides a medical patch comprising an adhesive composition comprising risperidone or a pharmaceutically acceptable salt thereof; a carboxylic acid; a fatty acid ester; and an adhesive, characterized in that said adhesive is a star-shaped acrylic block polymer having a star-shaped structure in which at least three chain polymer portions radiate from a sulfur residue of a mercapto group situated at the center, wherein the (meth)acrylic acid alkyl ester structural units having 7-17 carbon atoms account for 30-99.99% by mass of the whole structural units in said star-shaped acrylic block polymer, and at least one of said chain polymer portions has a structural unit having a copolymer structure of polymerizable monomers comprising a (meth)acrylic acid alkyl ester having 7-17 carbon atoms and a polyfunctional monomer.Type: ApplicationFiled: April 4, 2018Publication date: April 9, 2020Applicant: TEIKOKU SEIYAKU CO., LTD.Inventors: Satoshi KAWAKAMI, Manabu SOGABE, Taiki SHIBATA, Hiroaki HASEGAWA
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Patent number: 10335389Abstract: The present invention provides a patch containing beraprost or a pharmacologically acceptable salt thereof, which achieves high transdermal absorption of beraprost or a pharmacologically acceptable salt thereof and has excellent formulation properties.Type: GrantFiled: August 7, 2014Date of Patent: July 2, 2019Assignee: TEIKOKU SEIYAKU CO., LTD.Inventors: Satoshi Kawakami, Manabu Sogabe, Taiki Shibata
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Patent number: 10137098Abstract: Provided is a novel transdermal absorption preparation containing silodosin or tamsulosin, or salt thereof as an active ingredient, wherein the transdermal absorption preparation is capable of keeping a dissolved state for a long time, as well as has a high permeability to a skin, and can effectively and sustainably exert the transdermal absorbability. A transdermal absorption preparation containing the transdermal absorption preparation comprises an acrylic pressure-sensitive adhesive that comprises a copolymer of at least one (meth)acrylic acid monomer and at least one vinyl monomer and that contains a carboxyl group, and at least one transdermal absorption promoting agent selected from the group consisting of oleyl alcohol, lauryl alcohol, and lauromacrogol.Type: GrantFiled: May 20, 2015Date of Patent: November 27, 2018Assignee: TEIKOKU SEIYAKU CO., LTD.Inventors: Satoshi Kawakami, Taiki Shibata, Manabu Sogabe
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Publication number: 20180280315Abstract: The present invention provides a star-shaped acrylic block polymer having a star-shaped structure in which at least three chain polymer portions radiate from a mercapto group situated at the center, wherein (meth)acrylic acid alkyl ester structural units having 7-17 carbon atoms account for 30-99.9% by mass of whole structural units of the star-shaped acrylic block polymer, and at least one of the chain polymer portions has a copolymer structure of polymerizable monomers containing a (meth)acrylic acid alkyl ester having 7-17 carbon atoms and a weakly basic monomer; and a medical patch containing an adhesive composition containing a salt of a basic drug and the star-shaped acrylic block polymer as an adhesive that exhibits high drug efficacy, that does not cause a decrease in adhesive property of an adhesive base due to an additive, and that causes less skin irritation.Type: ApplicationFiled: September 30, 2016Publication date: October 4, 2018Applicants: TEIKOKU SEIYAKU CO., LTD., NIPPON SHOKUBAI CO., LTD.Inventors: Satoshi KAWAKAMI, Manabu SOGABE, Taiki SHIBATA, Yasushi HORIKAWA, Hiroaki HASEGAWA
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Publication number: 20170079940Abstract: Provided is a novel transdermal absorption preparation containing silodosin or tamsulosin, or salt thereof as an active ingredient, wherein the transdermal absorption preparation is capable of keeping a dissolved state for a long time, as well as has a high permeability to a skin, and can effectively and sustainably exert the transdermal absorbability. A transdermal absorption preparation containing the transdermal absorption preparation comprises an acrylic pressure-sensitive adhesive that comprises a copolymer of at least one (meth)acrylic acid monomer and at least one vinyl monomer and that contains a carboxyl group, and at least one transdermal absorption promoting agent selected from the group consisting of oleyl alcohol, lauryl alcohol, and lauromacrogol.Type: ApplicationFiled: May 20, 2015Publication date: March 23, 2017Applicant: TEIKOKU SEIYAKU CO., LTD.Inventors: Satoshi KAWAKAMI, Taiki SHIBATA, Manabu SOGABE
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Publication number: 20160193178Abstract: The present invention provides a patch containing beraprost or a pharmacologically acceptable salt thereof, which achieves high transdermal absorption of beraprost or a pharmacologically acceptable salt thereof and has excellent formulation properties.Type: ApplicationFiled: August 7, 2014Publication date: July 7, 2016Applicant: TEIKOKU SEIYAKU CO., LTD.Inventors: Satoshi KAWAKAMI, Manabu SOGABE, Taiki SHIBATA
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Publication number: 20020137831Abstract: Disclosed is a polymeric PTC composition comprising an organic polymer and conductive particles having a melting point of not less than 2000° C. dispersed therein and a circuit protection device comprising a PTC element comprising the PTC composition which are treated with a coupling agent and at least two electrodes which are electrically connected to the PTC element. The polymeric PTC composition is used to provide a circuit protection device having excellent environmental resistance properties, which exhibits a low resistance under normal operating conditions, and protects the circuit against the over-current even under large electric current and high voltage.Type: ApplicationFiled: April 20, 2000Publication date: September 26, 2002Inventors: Hideo Horibe, Itsuo Nishiyama, Osamu Hiroi, Teijiro Mori, Tatsuya Hayashi, Chie Takahashi, Shiro Murata, Kenichi Nishina, Manabu Sogabe, Masahiro Ishikawa
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Patent number: 5250920Abstract: Assembly of a remote controlled relay has steps of: previous assembling of units which are constituted by components having a concern with each other; positioning of the units on a base member; soldering of wires of electric components; coupling on the units which have mechanical concern; and covering of the units by a cover member which is fit and fixed to the base member.Type: GrantFiled: November 27, 1991Date of Patent: October 5, 1993Assignee: Mitsubishi Denki Kabushiki KaishaInventors: Hiroaki Fujihisa, Manabu Sogabe
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Patent number: 5248951Abstract: In a remote controlled relay having a manual operation handle coupled to a plunger of an electromagnetic device, a relatively large clearance in a coupling part allows for free movement of the plunger without any interference except a friction force thereof even when the operation handle is stopped at a deadlock point between an ON position and an OFF position.Type: GrantFiled: January 14, 1992Date of Patent: September 28, 1993Assignee: Mitsubishi Denki Kabushiki KaishaInventors: Manabu Sogabe, Hiroaki Fujihisa, Shuji Matsumoto
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Patent number: 5200723Abstract: A remotely controlled relay having a lever and a link, both of which being driven by a bistable polar electromagnet device. The lever drives a switch circuit to open and close while the link operates the main-circuit opening-and-closing assembly. A current is supplied to the coil of the bistable polar magnet device from an external circuit and magnetizes the plunger such that the plunger moves through a stroke between a first and second positions. When the plunger arrives at the center of its stroke while the plunger is moving from the first position to the second position, the lever causes the micro-switch to switch from the a first contact position to a second contact position. When the plunger arrives at the center of plunger stroke while the plunger is moving from the second position to the first position, the lever causes the micro-switch to switch from the second contact position to the first contact position.Type: GrantFiled: May 22, 1991Date of Patent: April 6, 1993Assignee: Mitsubishi Denki Kabushiki KaishaInventors: Hiroaki Fujihisa, Manabu Sogabe
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Patent number: 5181001Abstract: A remotely controlled relay having a lever and a link, both of which being driven by a bistable polar electromagnet device. The lever is also manually operable. The lever drives a switch circuit to open and close while the link operates the main-circuit opening-and-closing assembly. The display provided on the lever indicates the open and closed conditions of the main circuit. A current is supplied to the coil of the bistable polar magnet device from an external circuit and magnetizes the plunger such that the plunger moves through a stroke between a first and second positions. When the plunger arrives at the center of its stroke while the plunger is moving from the first position to the second position, the lever causes the micro-switch to switch from the a first contact position to a second contact position.Type: GrantFiled: May 22, 1991Date of Patent: January 19, 1993Assignee: Mitsubishi Denki Kabushiki KaishaInventors: Hiroaki Fujihisa, Manabu Sogabe
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Patent number: 5172086Abstract: A remotely controlled relay having two micro-switches driven to open and close by the plunger of a bistable polar electromagnet device. A current is supplied to the coil of the electromagnet device from an external power source to magnetize the plunger so that the plunger is moved through a stroke between a first position and a second position. When the plunger moves from the first position to the second position, a first micro-switch is closed to energize the coil in a first direction until the plunger passes through the middle of the stroke. When the plunger moves from the second position to the first position, a second micro-switch is closed to energize the coil in a second direction until the plunger passes through the middle of the stroke.Type: GrantFiled: May 22, 1991Date of Patent: December 15, 1992Assignee: Mitsubishi Denki Kabushiki KaishaInventors: Hiroaki Fujihisa, Manabu Sogabe
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Patent number: 5079529Abstract: A remote-controlled circuit breaker has an operation mechanism unit (300), for selecting one of an off state and a remote-controllable state of the circuit breaker, and a movable contact (11, 12) which makes/breaks contact with a fixed contact (9.16) in connection with a motion of an electromagnetic unit (200) only in the remote-controllable state; and the movable contact breaks contact with the fixed contact irrespective of the motion of the electromagnetic unit at the time when an overcurrent tripping unit (400) is operated by a fault. A control lever (63) for moving the movable contact into and out of contact with the fixed contact has an elastic element (63A) which strengthens the engagement of a latch mechanism in the overcurrent tripping unit during an off-time of the electromagnetic unit.Type: GrantFiled: October 3, 1989Date of Patent: January 7, 1992Assignee: Mitsubishi Denki Kabushiki KaishaInventors: Hirotoshi Ohishi, Tatunori Ikeda, Manabu Sogabe
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Patent number: 5053735Abstract: A remotely operated circuit breaker comprises a handle which is selectively positioned at one of three operating positions: a handle off position into which the handle is manually positioned to forcibly open the electrical contacts in the circuit breaker; a handle auto position into which the handle is positioned manually so that the electrical contacts are driven to normally open and close by a control mechanism which in turn is controlled by an electromagnetic driving unit response to a remote control voltage applied thereto; and a trip position into which the handle is automatically positioned by the control mechanism and a forcible overcurrent protecting unit to and the electrical contacts are opened rapidly when an overcurrent as well as a short-circuit current flows through the electrical contacts.Type: GrantFiled: October 6, 1989Date of Patent: October 1, 1991Assignee: Mitsubishi Denki Kabushiki KaishaInventors: Hirotoshi Ohishi, Tatsunori Ikeda, Manabu Sogabe
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Patent number: 5041805Abstract: A remote-controlled circuit breaker has an operation mechanism unit, for selected one of an off state and a remote-controllable state of the circuit breaker, and a movable contact which makes/breaks contact with a fixed contact in connection with a motion of an electromagnetic unit only in the remote-controllable state; and the movable contact breaks contact with the fixed contact irrespective of the motion of the electromagnetic unit at the time when an overcurrent tripping unit is operated by a fault. A push rods acts in conjunction with a transmission lever to either provide an indication of the state of contact connection or to actuate tripping. An indication mechanism is also disclosed.Type: GrantFiled: October 3, 1989Date of Patent: August 20, 1991Assignee: Mitsubishi Denki Kabushiki KaishaInventors: Hirotoshi Ohishi, Tatunori Ikeda, Manabu Sogabe