Patents by Inventor Manabu Takahisa

Manabu Takahisa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fibrinogen-producing transgenic silkworm
    Patent number: 9447167
    Abstract: Disclosed is a novel means that enables mass production of highly safe fibrinogen at low cost. The transgenic silkworm of the present invention expresses the fibrinogen subunit A?, B? and ? chains in the silk gland cells and produces fibrinogen having coagulation activity in the cocoon filament. Preferably, the transgenic silkworm expresses the subunits in the middle silk gland cells and produces fibrinogen in the sericin layer of the cocoon filament. By recovering fibrinogen from the cocoon of the transgenic silkworm of the present invention, highly safe fibrinogen can be mass-produced at low cost.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: September 20, 2016
    Assignee: IMMUNO-BIOLOGICAL LABORATORIES CO., LTD
    Inventors: Satoshi Sekiguchi, Manabu Takahisa, Masahiro Tomita
  • FIBRINOGEN-PRODUCING TRANSGENIC SILKWORM
    Publication number: 20130345401
    Abstract: Disclosed is a novel means that enables mass production of highly safe fibrinogen at low cost. The transgenic silkworm of the present invention expresses the fibrinogen subunit A?, B? and ? chains in the silk gland cells and produces fibrinogen having coagulation activity in the cocoon filament. Preferably, the transgenic silkworm expresses the subunits in the middle silk gland cells and produces fibrinogen in the sericin layer of the cocoon filament. By recovering fibrinogen from the cocoon of the transgenic silkworm of the present invention, highly safe fibrinogen can be mass-produced at low cost.
    Type: Application
    Filed: March 2, 2012
    Publication date: December 26, 2013
    Applicant: IMMUNO-BIOLOGICAL LABORATORIES CO., LTD.
    Inventors: Satoshi Sekiguchi, Manabu Takahisa, Masahiro Tomita