Patents by Inventor Manal A. Swairjo

Manal A. Swairjo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystal Structure of Queuosine Biosynthesis Enzyme QueF Bound to Substrate PreQ0
    Publication number: 20150269310
    Abstract: This invention provides for the design of novel nitrile oxidoreductases that can be used as biocatalysts for industrial chemical processes and; and thus, provide attractive alternatives to traditional chemical synthesis. Generally, this technology relates to crystal structures of nitrile oxidoreductases, and of crystal structures of nitrile oxidoreductases complexed with substrates and co-factors. For example, the invention provides for the crystalline structure of the nitrile oxidoreductase, QueF, as well as for a computer-readable medium having QueF crystal structure information stored thereon.
    Type: Application
    Filed: March 30, 2015
    Publication date: September 24, 2015
    Inventors: Dirk IWATA-REUYL, Manal A. SWAIRJO
  • Crystal structure of queuosine biosynthesis enzyme QueF bound to substrate PreQ0
    Patent number: 8993293
    Abstract: This invention provides for the design of novel nitrile oxidoreductases that can be used as biocatalysts for industrial chemical processes and; and thus, provide attractive alternatives to traditional chemical synthesis. Generally, this technology relates to crystal structures of nitrile oxidoreductases, and of crystal structures of nitrile oxidoreductases complexed with substrates and co-factors. For example, the invention provides for the crystalline structure of the nitrile oxidoreductase, QueF, as well as for a computer-readable medium having QueF crystal structure information stored thereon.
    Type: Grant
    Filed: December 30, 2010
    Date of Patent: March 31, 2015
    Inventors: Dirk Iwata-Reuyl, Manal A. Swairjo
  • Crystal of GTP Cyclohydrolase Type IB
    Patent number: 8328934
    Abstract: This invention relates to a novel, bacterial GTP Cyclohydrolase Type IB enzyme, and the crystal structure thereof.
    Type: Grant
    Filed: April 8, 2010
    Date of Patent: December 11, 2012
    Assignee: Western University of Health Sciences
    Inventors: Manal A. Swairjo, Dirk Iwata-Reuyl, Valerie de Crecy-Lagard
  • Crystal Structure of Queuosine Biosynthesis Enzyme QueF Bound to Substrate PreQ0
    Publication number: 20110295582
    Abstract: This invention provides for the design of novel nitrile oxidoreductases that can be used as biocatalysts for industrial chemical processes and; and thus, provide attractive alternatives to traditional chemical synthesis. Generally, this technology relates to crystal structures of nitrile oxidoreductases, and of crystal structures of nitrile oxidoreductases complexed with substrates and co-factors. For example, the invention provides for the crystalline structure of the nitrile oxidoreductase, QueF, as well as for a computer-readable medium having QueF crystal structure information stored thereon.
    Type: Application
    Filed: December 30, 2010
    Publication date: December 1, 2011
    Inventors: Dirk IWATA-REUYL, Manal A. Swairjo
  • NOVEL GTP CYCLOHYDROLASE TYPE IB
    Publication number: 20100291608
    Abstract: This invention relates to a novel, bacterial GTP Cyclohydrolase Type IB enzyme, and the crystal structure thereof.
    Type: Application
    Filed: April 8, 2010
    Publication date: November 18, 2010
    Applicant: WESTERN UNIVERSITY OF HEALTH SCIENCES
    Inventors: Manal A. SWAIRJO, Dirk IWATA-REUYL, Valerie de CRECY-LAGARD
  • Crystal structures of anti-factor IX Fab fragments and methods of use for peptidomimetic design
    Publication number: 20050181982
    Abstract: Novel anti-Factor IX Fab fragment crystalline structures are identified.
    Type: Application
    Filed: April 13, 2005
    Publication date: August 18, 2005
    Inventor: Manal Swairjo
  • Crystal structures of anti-Factor IX Fab fragments and methods of use for peptidomimetic design
    Publication number: 20030069700
    Abstract: Novel anti-Factor IX Fab fragment crystalline structures are identified.
    Type: Application
    Filed: May 13, 2002
    Publication date: April 10, 2003
    Applicant: SmithKline Beecham Corporation
    Inventor: Manal A. Swairjo